Báo cáo y học: " Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41" pdf

... involved in the study. JPM partici-pated in the study design and coordination. BB supervised the study, and participated in its design and coordination.All authors read and approved the final manuscript.AcknowledgmentsWe ... approxi-mately 4 days compared to the wt virus. Replication of the Q591L mutant was significantly better, with a delay of only one day compared to the wt virus. Of note is that the double mutant L593Q ... electroporation. The cultureswere inspected regularly for the emergence of revertantviruses, using CA-p24 ELISA and/ or the appearance of syncytia as indicators of virus replication. At regular inter-vals,...

Báo cáo y học: "Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors" pdf

... Analysis of synonymous and non-synonymous mutation in the plasma virus and proviral compartments. Shown are p-distancevalues for plasma (A) and proviral (B) sequences as determined by comparing ... sequenceanalysis and participated in study design. RFS participated in study design and helped to draft the manuscript JNB conceived of the study, and participated in its design and coordination and ... changesseen in plasma virus and these were mostly synonymousmutations. Taken together, these data illustrate that over-all there is significantly more synonymous mutation thannon-synonymous...

Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf

... (MS)Glyoxylate  H2O  acetyl-CoA ! malate  CoASHMS (EC 4.1.3.2) catalyzes the transfer of the acetyl moeity of acetyl-CoA to glyoxylate to yieldL-malate. The glyoxy-somal enzyme has been isolated ... considers the evolution of all of the enzymes of the pathway (Fig. 4), it is clear that only about half of the enzymes of the tricarboxylic acid cycle, the major pathway of carbon metabolism in ... catalyzed by PDH(oxidative decarboxylation of an organic acid with a ketogroup at the a carbon) is mechanistically very similar to the reactions catalyzed by OGDH and by branched-chain a- oxoacid...

Báo cáo y học: " Evolution of the uniquely adaptable lentiviral envelope in a natural reservoir host" potx

... SMs and African green mon-keys (AGMs) [56-63] by demonstrating that viruses foundwithin a single animal can vary by greater than 35% at the aa level. The ranges of aa diversity in some intra-host ... naturally SIV-infected SMs from the colony at the Yerkes National Primate Research Center,Atlanta, GA were chosen for study. Individual animalswere between 8 and 12 years of age and were estimated ... performedstatistical and phylogenetic analyses of the sequence data.LJD, THV, and SIS wrote the manuscript. All authors read and approved the final manuscript.AcknowledgementsWe dedicate this paper...

Báo cáo y học: "Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition" pdf

... and bacterial disease specificity. J Infect Dis2005, 192:760-770.81. Nakagawa I, Kurokawa K, Yamashita A, Nakata M, Tomiyasu Y, Oka-hashi N, Kawabata S, Yamazaki K, Shiba T, Yasunaga T, et al.:Genome ... respectively. The arrow locates the concatenated tree. (a) (b) (c) (a) (b) (c)S. agalactiae recombination heatmapsFigure 6S. agalactiae recombination heatmaps. The layout is the same as Figure ... while also extending the estimates to additional taxa of Streptococcus, and lineages of S. agalactiae and S. pyo-genes, and we would certainly concur with these authors thatmuch of this gene gain...

Báo cáo Y học: Interaction of the GTS1 gene product with glyceraldehyde3-phosphate dehydrogenase 1 required for the maintenance of the metabolic oscillations of the yeast Saccharomyces cerevisiae pdf

... (5¢-3¢)15¢-CCCGAAGCATGCTGTGCCTAC-3¢25¢-CCCGAAGCATGCTGTGCTCAC-3¢35¢-GGAGAATTCGTTGGGCTGAGCTTCTGATCC-3¢45¢-TTGGGATCCTTAAGCCTTGGCAACATATTC-3¢55¢-CTTTGAATTCTGCTGTAACCCGTACATGCC-3¢65¢-ATTAGAATTCGCGGCTAAAGTTAAGCATGC-3¢75¢-GAAAACTGGATCCGACTTGTATGCTAAAGG-3¢85¢-TTGGGATCCTTAAGCCTTGGCAACATATTC-3¢95¢-GAAAACTGGATCCGACTTGTATGCTAAAGG-3¢10 5¢-TAATAGGAATTCTGATCATTTTGTTTTGTG-3¢11 5¢-AACAAGAATTCATGGTTAGAGTTGC-3¢12 ... 5¢-AACAAGAATTCATGGTTAGAGTTGC-3¢12 5¢-AGGAGCTCGAGTTAAGCCTTGGCAAC-3¢13 5¢-AACTAACTAGTACTTGTATGCTAAAGG-3¢14 5¢-TTGTGTGTGTTGGTGAAATATCAAACCAAGTTCTTGATGAATTTC-3¢15 5¢-GTGTATTTTTCTTCGTTAACACCCATGACGAACATTGGGGCGGTG-3¢Fig. ... (5¢-3¢)15¢-CCCGAAGCATGCTGTGCCTAC-3¢25¢-CCCGAAGCATGCTGTGCTCAC-3¢35¢-GGAGAATTCGTTGGGCTGAGCTTCTGATCC-3¢45¢-TTGGGATCCTTAAGCCTTGGCAACATATTC-3¢55¢-CTTTGAATTCTGCTGTAACCCGTACATGCC-3¢65¢-ATTAGAATTCGCGGCTAAAGTTAAGCATGC-3¢75¢-GAAAACTGGATCCGACTTGTATGCTAAAGG-3¢85¢-TTGGGATCCTTAAGCCTTGGCAACATATTC-3¢95¢-GAAAACTGGATCCGACTTGTATGCTAAAGG-3¢10...

Báo cáo y học: "Phase delaying the human circadian clock with a single light pulse and moderate delay of the sleep/dark episode: no influence of iris color" potx

... samples were shipped on dry ice to Pharma-san Labs (Osceola, WI) and radioimmunoassayed formelatonin. The sensitivity of the assay was 0.7 pg/ml and the intra- and inter-assay coefficients of ... manuscript wealso re-analyzed data from our previous phase-advancingstudy with daily light pulses [42] that included both light and dark-eyed Caucasians as well as dark-eyed AfricanAmericans, and thus ... that suggestion, in our previous study [40] AfricanAmericans had larger phase advances than Caucasians.Because we found that African Americans had a shortertau than Caucasians, which would augment...

Báo cáo y học: "Intussusception of the appendix secondary to endometriosis: a case report" docx

... history of right iliacfossa pain and loose motions. Apart from longstandingdysmenorrhoea and menorrhagia, she did not have anyother symptoms. There was no past medical history tonote and no family ... carried out in the absence of anyother findings at laparotomy.On histology, the wall of the appendix had widespreadendometrial deposits [see Figures 2 and 3] and there wasno evidence of malignancy. ... surgeons and gynaecologists for a possi-ble right hemicolectomy, total abdominal hysterectomy and bilateral salpingo-oophorectomy. A preoperative CT scan of her abdomen and pelvis did notreveal any...

Báo cáo y học: "Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report" docx

... one other casewhere radiotherapy treatment of a laryngeal carcinoma has resulted in osteoradionecrosis of the cervical spine.Case presentation: We present the case of a 65 year old male patient ... literature, but cases of avascular necrosis of the cervical spine following radiotherapy to the larynxappear to be extremely rare. A review of the English language literature has shown only one ... reportFrederik Carl van Wyk*, Manu-priya Sharma and Robert TranterAddress: Department of Otolaryngology and Head and Neck Surgery, Brighton and Sussex University Hospitals NHS Trust, Eastern Road,Brighton,...

Báo cáo y học: " Evolution of Dengue Virus Type 3 Genotype III in Venezuela: Diversification, Rates and Population Dynamics" docx

... D, Garcia-Aguirre L, Gonzalez M,Mosquera C, Alava A, Fajardo A, Alvarez M, D’Andrea L, Dubra A, Martinez M, Khan B, Cristina J: Phylogenetic analysis of the NS5 gene of dengue viruses isolated ... the design of the study, acquisition of data, have performed phylogenetic analysis and contributed to the interpretation of the data. ZM, MG, GC, DC, GC, VA, JZ and RH have made substantial and ... INHRR, Ciudad Universitaria,Caracas, Venezuela.Authors’ contributionsJC and FL conceived of the study, and participated in its design and coordination. AR and AF have made substantial contributions...

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