Báo cáo y học: " γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa" pptx
Báo cáo y học: " γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa" pptx
... intracytoplasmic cytokine-producing αβ T cells (top) and γδ T cells (bottom) within total T lym- phocytes after 10 days of culture with cytosolic extract from Pseudomonas aeruginosa, followed by ... T cells. To assess the type of cytokines secreted in response to PA, intracytoplasmic IL-4, IFN-γ, TNF-α and IL-2 production from αβ and γδ T cells was determin...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: " Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells" doc
... 2. Competing interests The authors declare that they have no competing interests. Authors' contributions YX carried out part of the experiments, analyzed the data and wrote the draft of the ... in WT and CF DC with and without infection with P. aeruginosa were annotated using the NetAffx Analysis Center http:// www.affymetrix.com to retrieve the Gene Ontology (GO) annotations...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Rare association between cystic fibrosis, Chiari I malformation, and hydrocephalus in a baby: a case report and review of the literature" potx
... our patient, and contributed to the design, writing, and editing of the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have ... manuscript. Authors’ contributions AJP and VHR were major contributors in the writing and editing of the manuscript. AJ was a major contributor in the interpretation and analysis of...
Ngày tải lên: 10/08/2014, 23:22
Báo cáo y học: " A woman with cystic fibrosis, severe hypoxaemia, an atrial thrombus and a patent foramen ovale: a case report" pdf
... breathlessness. Inten- sive treatment with intravenous antibiotics and phy- siotherapy improved her FEV 1 to baseline but her oxygen saturation only partially corrected (90% in room air). One month later, ... blood count; U&Es, urea and electrolytes; LFTs, liver function tests; PT, prothrombin time; APTT, activated partial thromboplastin time; Fib, fibrinogen; ANA, antinuclear ant...
Ngày tải lên: 11/08/2014, 14:20
Báo cáo y học: "B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcgRIIb, which are modulated by anti-tumor necrosis factor therapy" potx
... demonstrated that FcgRIIa and FcgRIIb on human monocytes are differentially regulated by Th1/Th2 cytokines, with interferon-gamma favoring the activator receptor and interleukin-4 favoring the inhibitory ... FcgRIIb,which ,in contrast to FcgRIIa, has an immunoreceptor tyrosine- based inhibitory motif on the cytoplasmic domain. This characteristic confers an inhibitory function to t...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: " T cell receptor transgenic lymphocytes inflitrating murine tumors are not induced to express foxp3" potx
... Foxp3-positive CD4 T cells are enriched in tumor-infiltrating lymphocytes. Many groups have reported high percentages of Foxp3-positive lymphocytes infiltrating both murine and human tumors and ... recruited where they may exert their suppressive function [25]. Treg 15 (Treg), Induced Regulatory T cells (iTreg), Tumor Infiltrating Lymphocytes (TIL), Transforming Gr...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... agree" were combined into the "agreed" category. MTS = methylphenidate transdermal system; ITT = intent to treat, MSS = Medication Satisfaction Survey. Child and Adolescent Psychiatry ... failed to respond to psychostimulants in the past, and those with conduct disorder, were excluded from the study. Therefore, the results of this study should not be extrapolate...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... isolated from thermophilic bacteria are usually stable to heat and chemical denaturants, indicating that they must have most of the determinants of protein stability. Initial clues to the relationship ... Tyr34/Tyr43 cause a favorable electrostatic interaction. These side-chain interactions may contribute to the enhanced stability of HT c-552. It would be worth trying to mutate...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Pyruvate decarboxylase from Kluyveromyces lactis An enzyme with an extraordinary substrate activation behaviour pptx
... rate constant on the substrate concentration. The dissociation constants of the substrate at the regulatory and the catalytic site were determined and compared to other PDC species. MATERIALS AND ... slowly compared to the substrate binding. K a is the dissociation constant of the substrate binding to the regulatory site preceding the isomerization. The isomerization constant K is...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India" ppsx
... advancement in treatments, patients suffering from schizophrenia often do not have satisfac- tory outcomes in the long run. High rates of suicide attempt, disability, loss of vocation and inability to ... to multidisciplinary team management, a structured com- munity program, consistent treatment with atypical antip- sychotics for at least 3 to 4 years and were highly comp...
Ngày tải lên: 08/08/2014, 23:21