Báo cáo y học: "Bench-to-bedside review: Nitric oxide in critical illness - update 2008" pot

... decrease endotoxin-induced TNF synthesis in cultured cardiac myocytes by inhibiting L-type calcium channel-depen- dent ERK signaling, suggesting nNOS might modulate inflammatory signaling [9]. On ... = inducible nitric oxide synthase (NOS2); L-NMMA = N G -methyl-L-arginine; NF = nuclear factor; nNOS = neuronal nitric oxide synthase (NOS1); NO = nitric oxide; NOS = nitric oxide...

Ngày tải lên: 13/08/2014, 11:23

... reporting barriers partly owing to fewer liability concerns, and an opportunity to study recovery patterns [75]. Ideally, error reporting should be voluntary, anonymous, centralized to increase ... The technology permits clinicians to enter orders directly into a computer workstation that is linked to a hospital clinical infor- mation system [47]. The main advantages of these systems are that...

Ngày tải lên: 25/10/2012, 10:35

... Vivid dreams, hallucinations, psychosis and REM sleep in Guillain- Barre syndrome. Brain 2005, 128:253 5-2 545. 32. Hardin KA, Seyal M, Stewart T, Bonekat HW: Sleep in critically ill chemically paralyzed patients ... Cardiac dysrhythmia during sleep in the critically ill: a pilot study. Am J Crit Care 1996, 5:2 6-3 3. 26. Richards KC: Effect of a back massage and relaxation inter- v...

Ngày tải lên: 13/08/2014, 08:20

... marginal changes in recent years [11]. Peripheral vasodilatation typically manifests as a systemic hypotension, hypo- responsive to pressor agents, and an intrinsic myocardial dysfunction commonly masked by ... A-, B- and C-type natri- uretic peptides. Endocrinology 1998, 139:402 1-4 025. 44. Garbers DL: Guanylat cyclase receptors and their endocrine, paracrine, and autocrine ligands. Cel...

Ngày tải lên: 12/08/2014, 20:20

... to intensive care. Memory 2000, 8:7 9-9 4. 7. Kress JP, Gehlbach B, Lacy M, Pliskin N, Pohlman AJ, Hall JB: The long-term psychological effects of daily sedative interrup- tion on critically-ill ... discomfort as a less worrying problem and might even view it as (potentially) unavoidable. Illness severity in this study was moderate, as evidenced by the modest Acute Physiology and Chroni...

Ngày tải lên: 12/08/2014, 20:20

... decrease in iNOS expression in cytosol after inflammatory stimu- lation, inhibiting superoxide generation and resulting in prevention of tissue injury in patients with chronic air- way diseases, including ... bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts. Respir Res 2006, 7:1 6-2 9. 13. Tayler BS, Geller DA: Regulation o...

Ngày tải lên: 11/08/2014, 03:20

... cAMP inhibits inducible nitric oxide synthase expression and NF-κB-binding activity in cultured rat hepatocytes. J Surg Res 2001, 99:25 8-2 64. 38. St-Denis A, Chano F, Tremblay P, St-Pierre Y, Descoteaux ... bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts. Respir Res 2006, 7:1 6-2 9. 13. Tayler BS, Geller DA: Regulation...

Ngày tải lên: 11/08/2014, 06:22

... ONO1714 (1S,5R,6R,7R )-7 -chloro-3-imino- 5- methyl-2-azabicyclo [4.1.0]heptane hydrochloride, a fused piperidine derivative, is a competitive iNOS inhibi- tor with a high safety margin (maximum tolerance ... sensitivity in non- sensitized guinea pigs and OVA-induced increase in cough reflex sensitivity in sensitized guinea pigs; however, iNOS inhibition caused by ONO1714 partially...

Ngày tải lên: 13/08/2014, 10:20

... of NO in cardiac contractility is still under study. NO is produced by the conversion of L-arginine to L-citrulline by the nitric oxide synthase, which exists in inducible nitric oxide synthase ... of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs. J Clin Invest 1995, 95:36 0-3 66. 60. Sawyer DB, Colucci WS: Nitri...

Ngày tải lên: 12/08/2014, 19:21

... receptors IL-6, IL-2, IL-3, IL-8 + receptors IFN-γ IL-12 IL-18 GM-CSF IFN-α LT-α Anti-inflammatory cytokines IL-10 IL-1Ra IL-13 TGF-β 1 and TGF-β 2 IL-4 CTLA-4 CTLA, cytotoxic T-lymphocyte-associated ... TNF-α +250 GG genotype, again suggesting that polymorphisms may be ‘good’ or ‘bad’, depending on the outcome of interest. Interleukin-1 αα and interleukin-1 ββ IL-1, a potent proinflammatory...

Ngày tải lên: 12/08/2014, 19:22