Báo cáo y học: "Bench-to-bedside review: Optimising emergency reversal of vitamin K antagonists in severe haemorrhage – from theory to practice" pptx

... vitamin K alone is slow to take effect because of the time required for hepatic de novo synthesis of vitamin K- dependent coagulation factors. After intravenous vitamin K administration, the INR ... of eight patients requiring emergency reversal of phenpro- coumon, the mean baseline INR of 3.4 decreased to less than 1.3 within 10 minutes of administration of P...

Ngày tải lên: 13/08/2014, 11:23

... levels of total CK-18 and CK-18 fragments were comparable between the surviving and non-surviving subgroups at each Table 2 Comparison of inflammatory marker levels and cytokeratin measurements in ... neoepitope without detecting native or intact CK-18 [24,27] for assessing apop- tosis, in combination with measuring total CK-18 as an indirect marker for necrosis [28]. The aim of thi...

Ngày tải lên: 13/08/2014, 16:21

... noncompetitively inhibits ino- sine monophosphate dehydrogenase in the de novo purine synthesis pathway. This enzyme facilitates the conversion of inosine monophosphate to xanthine monophosphate, an inter- mediate ... McQuay HJ: An evaluation of homoge- neity tests in meta-analyses in pain using simulations of indi- vidual patient data. Pain 2000, 85:415-424. 33. L'Abbe KA,...

Ngày tải lên: 09/08/2014, 08:23

... timing of initiation of CRRT on outcomes of AKI. In the first of these studies, Gettings and colleagues [31] retrospectively analyzed the timing of initiation of continuous venovenous hemofiltration ... 32:80-86. 35. Liu KD, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM: Timing of initiation of dialysis in critically ill patients with acute kidney i...

Ngày tải lên: 13/08/2014, 08:20

... reactive oxygen species lead to inhibition of the glycolytic enzyme glyceraldhyde phosphate dehydrogenase and mitochondrial complexes I and IV, the basis of mitochondrial dysfunction likely to induce ... addressing intracranial hypertension in the ICU setting. Cerebrospinal fluid drainage Initial cerebrospinal fluid drainage may be a life-saving procedure particularly in the setti...

Ngày tải lên: 13/08/2014, 11:23

... high-pitched inspiratory wheeze) and signs of respiratory distress. Signs of respiratory distress are a prolonged inspiratory phase and recruitment of accessory respiratory muscles as seen by subcostal, ... predictor for the severity of adverse effects. Although every patient with symptoms has some degree of injury, not all injuries present clinically [2,17]. Laryngeal edema there...

Ngày tải lên: 13/08/2014, 19:20

... were localized to the extracellular space determined that many of the protein products of these genes were involved in a variety of activities, including chemokine/cytokine activity – including macrophage ... regulated kinase (ERK)/ mitogen-activated protein kinase pathway (reviewed in [14]). TNF initiates the activation of ERK/mitogen-activated protein kinase through the a...

Ngày tải lên: 09/08/2014, 01:22

... 46:902-907. 6. Terato K, Shimozuru Y, Katayama K, Takemitsu Y, Yamashita I, Miy- atsu M, Fujii K, Sagara M, Kobayashi S, Goto M, et al.: Specificity of antibodies to type II collagen in rheumatoid arthritis. ... antibody assay in rheumatoid arthritis. Int Orthop 1992, 16:272-276. 16. Cook AD, Rowley MJ, Stockman A, Muirden KD, Mackay IR: Spe- cificity of antibodies to type II...

Ngày tải lên: 09/08/2014, 01:23

... body's major storage site of vitamin B 6 , may turn over very slowly during inflammation. Low vitamin B 6 status is unlikely to be due to lower intake or excessive excretion Dietary intake ... defi- ciency in humans. In young healthy males receiving a defined diet restricted in vitamin B 6 , the muscle content of vitamin B 6 is relatively resistant to vitamin...

Ngày tải lên: 09/08/2014, 07:20

... amino-terminal two repeats of the death effector domain (DED), it lacks the carboxy-terminal half of the proteolytic domain. Caspase 8L binds to the Fas-asso- ciating protein with death domain ... reduction of adhesive properties of CPCs. One could logically consider the in vitro binding of CPCs to fibronectin as a reflection of the capacity of CPCs to bind to damaged...

Ngày tải lên: 09/08/2014, 10:20