Báo cáo y học: " Bench-to-bedside review: Hydrogen sulfide – the third gaseous transmitter: applications for critical care" pptx

... acid L-cysteine by either cystathionine-β-synthase or Review Bench-to-bedside review: Hydrogen sulfide – the third gaseous transmitter: applications for critical care Florian Wagner 1 , Pierre Asfar 2,3 , ... Bhatia M: Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK–NF- κκ B pathway. J Leukoc B...

Ngày tải lên: 13/08/2014, 11:23

... inflam- matory disorders. Abbreviations H 2 S: Hydrogen sulfide; NaHS: Sodium hydrosulfide; MPO: Myeloperoxidase; CBS: Cystathionine β-synthetase; CSE: Cystathionine γ-lyase; PAG: DL-propargylglycine; TMB: ... level, tissue H 2 S syn- thesizing enzyme activity and CSE expression were increased and inhibition of H 2 S synthesis by DL-propar- gylglycine (PAG) treatments reduced the inflamm...

Ngày tải lên: 11/08/2014, 08:22

... Wagner F, Asfar P, Calzia E, Radermacher P, Szabo C: Bench-to-bedside review: Hydrogen sulfide - the third gaseous transmitter: applications for critical care. Crit Care 2009, 13:213. 10. Blackstone ... Sekiguchi F, Kawabata A: Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. Toxicology 2007, 241:92-97. 15. Ali MY, Ping CY, M...

Ngày tải lên: 13/08/2014, 21:21

... that hypothermia itself reduces the metabolic rate (Q 10 effect). Therefore, in the current study, body t emperature was kept at 37°C throughout the experiment to exclude any effects of hypothermia ... of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice. Crit Care Med 2010, 38:588-595. 31. Bhambhani Y, Burnham R, Snydmiller G, MacLean I: Effects of 10-pp...

Ngày tải lên: 14/08/2014, 07:21

... time for the left ventricle due to tachycardia, and by tachycardiomyopathy [8,44]. Tachycardiomyopathy can occur as soon as 24 hours after the start of AF [44]. Conclusion on morbidity In all ... increased morbidity. This is reflected by the number of reported symptoms and by the days spent in the ICU and in the hospital. Haemodynamic parameters also tend to be worse in patients...

Ngày tải lên: 25/10/2012, 10:35

... selectivity. The efficiency of V 2 R–G s cou- pling can be modulated by the length of the central portion of the third intracellular loop [57], whereas the second intracel- lular loop of the V 1 R is critically ... G- proteins of the G q/11 family. The α-subunits regulate the activ- ity of the β-isoforms of phospholipase C [29]. A variety of signaling pathways is associ...

Ngày tải lên: 12/08/2014, 19:22

... peptide – Serotonin – Prostacyclin – Neuropeptide Y – Hypoxia Coronary Hypoxia Pulmonary BK Ca Angiotensin II Coronary β-Adrenoreceptor Coronary, aorta Thromboxane a 2 agonist Coronary Nitric ... phosphorylates the regulatory light chain of myosin. Phosphorylated myosin acti- vates myosin ATPase by actin and the cycling of myosin cross-bridges along actin filaments, whic...

Ngày tải lên: 12/08/2014, 19:22

... However, up to 10% of these cases will be ANCA negative [17]. They can affect many organ systems, and clinically are differentiated by their predilection for the pulmonary system (Table 2). No ... critical care physician in their diagnosis and management. Keywords antineutrophil cytoplasmic antibody, critical care, Churg–Strauss syndrome, diagnosis, microscopic polyangiitis, polyarter...

Ngày tải lên: 12/08/2014, 20:20

... may dramatically reduce oxygen delivery to the tissues. On admission to the ICU patients with fulminant vasculitis may be hypotensive because of a combination of dehydration, haemorrhage and systemic ... pulmonary physician in critical care – illustrative case 3: pulmonary vasculitis. Thorax 2003, 58:543- 546. 2. Fauci AS, Katz P, Haynes BF, Wolff SM: Cyclophosphamide therapy of sev...

Ngày tải lên: 12/08/2014, 20:20

... reason for the decline in autopsy rates is the growing reluctance of pathologists to perform autopsies. Several studies analyzing the delay of pathology reports show a long delay (up to 90 days) ... article has the goal of convincing intensivists of the role of autopsy and gives an overview of the studies performed in the ICU. Reasons for the decline in autopsy rate...

Ngày tải lên: 13/08/2014, 20:21