Báo cáo y học: " Bench-to-bedside review: Oxygen as a drug" pot

... regula tors, kinases, Rho and RAS GTPases, phosphatases, structural proteins, metabolic enzymes, and SUMO ligases. Kinases and phosphatases Kinases phosphorylate downstream proteins in active ... sepsis. Another kinase – apoptosis- signaling kinase-1, a member of the mitogen-activated protein kinase kinase kinase family – activates the p38 and the JNK pathways by directly phosphorylatin...

Ngày tải lên: 13/08/2014, 21:21

... variety of vascular and inflam- matory mediators that trigger local inflammation [38] and may lead to a systemic inflammatory response (SIR) that in many cases culminates in multiple organ dysfunction ... Yogaratnam JZ, Laden G, Madden LA, Seymour AM, Guvendik L, Cowen M, Greenman J, Cale A, Griffin S: Hyprbaric oxygen: a new drug in myocardial revascularization and protection? Cardivas...

Ngày tải lên: 13/08/2014, 11:23

... degenerated acetabulum. The loose bullet fragment was removed easily and an un-cemented total hip arthroplasty (Protek, Mathys Medical) was performed (figure 2). Lead deposits were seen in the synovium ... postoperative radiograph after total hip arthroplastyFigure 2 Showing postoperative radiograph after total hip arthro- plasty. Showing presence of intraarticular bullet in right hip joint...

Ngày tải lên: 11/08/2014, 10:23

... Boston, Massachusetts, USA and 3 HIV unit, 1st IKA Hospital, Athens, Greece Email: Matthew E Falagas* - m.falagas@aibs.gr; Efstathia A Zarkadoulia - e.zarkadoulia@aibs.gr; Paraskevi A Pliatsika - ... health sta- tus [6,36]. It may change over time, as the health status or the patients' beliefs and attitude regarding the disease, the physician, and the treatment may alter, as we...

Ngày tải lên: 13/08/2014, 06:20

... mammalian hosts. These animals, usually pigs, act as a transformer or converters; creating a strain that can more readily infect humans. Pigs can be infected with both avian and human influenza A ... Influenza was not a reportable disease: the only evidence of the early occurrence was the registration of deaths reported as uncomplicated cases of pneumonia by physicians to va...

Ngày tải lên: 02/11/2012, 11:12

... 2435 MINIREVIEW Na + /K + -ATPase as a signal transducer Zijian Xie and Amir Askari Department of Pharmacology, Medical College of Ohio, Toledo, USA Na + /K + -ATPase as an energy transducing ion pump has been ... to mitochondrial ROS generation, but also to the activation of p42/44 MAPK (also called ERK 1/2 ) through the Ras/Raf/ MAPK kinase/MAPK cascade (where Raf is a MAPK kinase k...

Ngày tải lên: 24/03/2014, 00:21

... 35 S-methio- nine (Trans- 35 S label; ICN Biochemicals, Costa Mesa, CA, USA) and RNasin ® Ribonuclease Inhibitor (Stratagene) as recommended by the manufacturer (Promega). Translation was carried out at 30°C ... differently from alanyl tRNA synthetase in another Western blot analysis (data not shown) and did not share any apparent crossreactive epitopes with the 49 kDa antigen. Western bl...

Ngày tải lên: 09/08/2014, 07:20

... obtained from animals cannot always be extrapolated to humans. Bjelle [36] has analysed the mechanical response of human knees and found an increase in glycosaminoglycan production in load- bearing ... consequently a lower response capacity. Another possibility is that OA chondrocytes may be less sensitive to loading response. Lastly, other inflammatory factors may act on chondrocytes mainl...

Ngày tải lên: 09/08/2014, 08:22

... article Quantitative gait analysis as a method to assess mechanical hyperalgesia modulated by disease-modifying antirheumatoid drugs in the adjuvant-induced arthritic rat Shabana Usman Simjee 1 , ... of their systemic, gastric and renal toxicities [5-11]. These cur- rently available analgesic and anti-inflammatory drugs are clearly not adequate therapy. In addition to these classical av...

Ngày tải lên: 09/08/2014, 10:21

... defined as normal or pathological according to standard laboratory normal values. These varia- bles were dependent in a logistic forward regression analyses with resistin as the independent variable. ... Maria Bokarewa and Hans Carlsten Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Göteborg University Guldhedsgatan 10, S-413 46 Göteborg, Sweden Correspond...

Ngày tải lên: 09/08/2014, 10:22