Báo cáo y học: "Norepinephrine weaning in septic shock patients by closed loop control based on fuzzy logic" docx

... norepinephrine as determined by a closed- loop control based on fuzzy logic algorithm versus manual control by the clinician in patients with septic shock. Our goal was to reduce the duration of ... 8:338-353. Key messages • The weaning rate of catecholamines is usually chosen empirically by intensivists. • A closed- loop control system based on fuzzy...

Ngày tải lên: 13/08/2014, 11:23

... citation purposes) finding may be explained by the less severe septic shock at the time of treatment initiation (drop in MAP of 10% in the present study vs. 30% in the latter study) and is in line ... treatment strategy for AVP in septic shock (constant low-dose infusion as a supplement to norepinephrine in catecholamine-resistant shock) might not represent the optimal...

Ngày tải lên: 13/08/2014, 18:22

... terlipressin (Glypressine ® ; Ferring Company, Berlin, Germany), which is the form of vasopressin that is present in pig. The first clinical trial evaluating the efficacy of terlipressin in septic shock ... effective in reversing catecholamine-resistant hypo- tension in patients with septic shock [14]. Vasopressin is not available in all countries, and some hospital pharma...

Ngày tải lên: 12/08/2014, 23:23

... the study by Abboud and colleagues confirms the few existing reports on catecholamine kinetics in critically ill patients with variable underlying pathology. Nevertheless, some intriguing aspects ... speculation. In conclusion, Abboud and colleagues confirm previous findings that catecholamines obey the (relatively simple) rules of linear kinetics with first-order elimination withou...

Ngày tải lên: 13/08/2014, 18:22

... re-laparotomy, and patients were re-operated on- demand exclusively. Septic shock definition Septic shock was defined according to the criteria of the Crit- ical Care Medicine Consensus Conference ... systematic treatment against Enterococci and yeasts in secondary peritonitis. Competing interests The authors declare that they have no competing interests. Authors' contributi...

Ngày tải lên: 13/08/2014, 16:21

... divided by the total number of tender points. Figure 1 Antipolymer antibody levels in fibromyalgia patients and in control individualsAntipolymer antibody levels in fibromyalgia patients and in control ... added, forming complexes with the polymer-bound antibodies. The bound enzyme–antibody conjugate was assayed by the addition of a single solution containing tetramethylbe...

Ngày tải lên: 09/08/2014, 10:20

... statement on a 5-point Likert-type scale (1 = strongly disagree; 5 = strongly agree). This study was reviewed and approved by the Institutional Review Boards at the University of Washington. Analyses We ... review of findings by clin- ical leadership. Methods We conducted two sets of psychometric analyses on cross- sectional, secondary data from three quality improvement projects cond...

Ngày tải lên: 11/08/2014, 05:21

... is minimal with the In- Tube test system, thus reducing the occupational haz- ards of performing TB testing. By introducing the M. tuber- culosis specific tests, we may be able to improve TB control by ... impaired by low sensitivity in patients with advanced immunodeficiency. The PHA control serves as a surrogate marker for anergy as well as a quality control of the assay....

Ngày tải lên: 12/08/2014, 16:20

... resuspended in 400 μl PBS-BSA. A white blood cell preparation was now made on a slide by cyt- ospin preparation at 75 × g for 6 min (Shandon Cytospin 2 centrifuge). After drying, the cell preparation ... reactions in this study, thereby possibly increasing the total amount of A. phagocytophilum DNA in the PCR reaction and thus increasing sensitivity. Other studies have shown that th...

Ngày tải lên: 12/08/2014, 18:22

... beneficial early in the course of septic shock if they reduce inflammation either by inhibiting the activation of NF-κB or by inducing a pro-apoptotic effect on activated circulating cells [1]. ... provided, either in the study by Forceville and colleagues or in any other published study of septic patients or in septic animal models. In contrast, inducing apoptosis...

Ngày tải lên: 13/08/2014, 08:20