... dividing the difference in peak inspiratory airway
pressure and the plateau inspiratory pressure, measured dur-
ing an end inspiratory pause, by the inspiratory flow preceding
the occlusion. The ... of end expiratory lung volume (EELV) measured by the helium dilution technique and the computed tomography (CT) scanComparison of end expiratory lung...
... diminishing mortality, in
patients with acute lung injury and also is likely to
prevent the development of lung injury when used as the
initial mode of ventilation [11-14]. erefore, the
clinically ...
clinically relevant questions now become whether
inhaled APC can diminish the severity of lung injury
when used in conjunction with low-tidal-volume ventila-
t...
... tomography in the assessment
of end expiratory lung volume Critical Care 2008, 12:R150.
Correction
Correction: Nitrogen washout/washin, helium dilution and
computed tomography in the assessment of end ... 0.0001). (b) The Bland-Altman plot of the EELV measurement obtained increasing the FiO
2
and the EELV obtained decreasing the
FiO
2
. The...
... V
T
MV, in the absence of infection, induced
up-regulation of TLR4 and down-regulation of IRAK3
and IBa proteinlevels,resultinginanincreaseofpro-
inflammatory cytokines levels in the lungs and in the ... levels
of pro-inflammatory cytokines in patients with acute
lung injury [5,31].
The ability of MV to induce inflammation may be in
part explained by its k...
... Simone
†‡
, Randy Wax
§¶
, Katherine G Craig** and Keith R Walley
††
*Resident, Department of Medicine, University of Toronto, Canada
†
Resident, Division of Thoracic Surgery, University of Toronto, ... is reasonable
and appropriate.
Con: steroids are not useful in the management of septic shock
Katherine G Craig and Keith R Walley
The debate surrounding the use of c...
... hypoxic
over the first 24 hours, requiring intubation and mechanical
ventilation. The patient is admitted to the intensive care unit
and, in the course of investigation, he has an abdominal
computed ... Cohn
4
1
Professor and Chief of Intensive Care and Accident Department, University Hospital Maastricht, The Netherlands
2
Trauma Surgeon and Intensivist, University...
... variation in insulin dosing in the cases
reporting the use of HIET in CCB overdose and in the
duration of treatment, rational recommendations could
currently consist of the administration of 1.0 ... hypokalaemia
may offer benefit by promoting cellular calcium entry and
increasing the inotropic effect of insulin [21,24].
Recommendations for the use of HIET...
... clarifying why oligomer formation is essential
for Rev activity by assessing the requirements for restora-
tion of the activity of the mutant.
Results
The intracellular localization of Rev and ... mutants
The intracellular distribution of the M4 and the M4
derived Rev mutants (schematically outlined in figure 1)
were tested by immunofluorescence in the absence...
... preference of the reverse transcriptase
enzyme for the Cy3 label and (ii) prolonged exposure to air and light of the dyes increasing
the chance of oxidation and / or bleaching. The main contributing ... presented by coefficient of
variance (CV). CVs are calculated by dividing the standard deviation (SD) by the mean ratio
of a gene and multiplying by 100%. Th...
... l-lysine, l-serine, b-alanine, taurine, sarcosine,
dimethylglycine, glycine betaine, trimethylamine N-oxide,
and cytidine 2¢-3¢ cyclic monophosphate were also obtained
from Sigma. These and other ... advances in understanding the
effect of osmolytes on protein stability, folding and the
activity of proteins and enzymes, the relationship
between protein stabilization by osm...