Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx
Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx
... bias with tight limits of agreement. TheseReviewBench -to- bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the ... (OD)ultrasound techniques as a measurement of cardiac output.They compared these against ITD cardiac output from the pulmonary artery catheter, which they described as having a precision of ± 20%. They suggested ... description of the error of that technique as obtained within the study. These concepts holdtrue for any study assessing a new methodology of measurement against a reference in clinical science.Worked...
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Báo cáo y học: "Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation" doc
... Any proning-related intervention that secondarily in uences IAP/IAH is likely to greatly in uence respiratory mechanics and outcomes. Further study of the role of IAP/IAH in the physiology ... (IAP) in association with the use of PV to explore the potential in uence of IAH. While early authors stressed the importance of gravitationally unloading the abdominal cavity to unencumber the ... concerning injured lungs in the setting of abdominal distension or IAH.Human studies E ect of proning on intra-abdominal pressure in humansEight studies measured IAP during PV in critically ill...
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Báo cáo y học: "Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis" ppt
... by proinflammatory cytokines in OA chondrocytes and was one of the key enzymes in the regulation of PGE2 production. mPGES-1 might be impor-tant in articular inflammation with cytokine-stimulated ... pathophysiology of OA has been demon-strated, the role of each PGES isoenzyme has not yet beendetermined. Accordingly, we studied the effects of variousinflammatory cytokines on the expression of ... maintaining homeostasis. In contrast, COX-2 is induced in inflammatory cells and tissues by various stimuli includ-ing cytokines, suggesting that COX-2 has a key role in the process of inflammation....
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Báo cáo y học: "Intravenous levosimendan-norepinephrine combination during off-pump coronary artery bypass grafting in a hemodialysis patient with severe myocardial dysfunctio" pps
... University of Ioannina School of Medicine, Ioannina, Greece.2Department of Cardiac Surgery, University of Ioannina School of Medicine,Ioannina, Greece.3Department of Anaesthesiology and Critical ... calcium-dependent binding to cardiac troponin C, thereby enhancing the calcium sensitivity of cardiac contractile proteins [3,4] and improving myocar-dial contractility, and (B) opening of ATP-dependentpotassium ... Editor -in- Chief of thisjournal.AbbreviationsACE inhibitors: Angiotensin-Converting Enzyme Inhibitors; ATP: AdenosineTri-Phospate; CABG: Coronary Artery Bypass Grafting; CAD: Coronary ArteryDisease;...
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Báo cáo y học: "Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al" doc
... patients. In practice, lack of efficacy with the standard dose of 3 mg/kg of infliximab results in many patients using higher doses; asmany as 61% of patients with rheumatoid arthritis after 1 year of ... andbiologically plausible, but they also fulfill the dose-effectcriterion for causality. The low risk in the comparison group may be real, the result of chance, or due to an as yet unclear systematic ... oranalysis flaw of all included randomized controlled trials. Weare wary of the interpretation of lower risk being due to chance or some other drug effect, which may give a falsesense of security...
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Báo cáo y học: " Meta-review of the effectiveness of computerised CBT in treating depression" pps
... Embase, CINAHL(EBSCO), the British Nursing Index, the CochraneLibrary, and PsycINFO. All systematic reviews examiningefficacy of cCBT for depression with or without anxiety in adults were included ... the outset, limited to the lastten years (initially search ing 1999 to 2009 , then updating to Feb 2011). The evolutionary development of cCBTand its reliance on ever-increasing speeds of internetcommunic ... discussed in the review.Beating the Blues: Package not directly discussed in the review.General conclusion of the review: There is evidence for progression in the field of internet-deliveredpsychotherapy.(cCBT:...
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Báo cáo y học: "Systematic review: The relation between nutrition and nosocomial pneumonia: randomized trials in critically ill patients" doc
... 1:3http://ccforum.com/Page 6 of 8Nutrition is integral to the care of an ICU patient. The method, site and timing of enteral nutrition mayhave a protective or predisposing influence on the risk of nosocomial infection ... were unlikely to beaware of the details of their care and were not partici-pating in assessment of the presence of nosocomialpneumonia. However, lack of blinding could haveaffected the care ... rate of pneumonia asso-ciated with enteral nutrition [23], in another study the pneumonia rate was significantly lower in the enteralnutrition group [24], and in the remaining two studies, the...
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Báo cáo y học: "Systematic review: Intra-aortic balloon counterpulsation pump therapy: a critical appraisal of the evidence for patients with acute myocardial infarction" doc
... werehemodynamic instability necessitating the use of an IABP,cardiogenic shock, bleeding diathesis prohibiting the use of aspirin or heparin, precatheterization administration of thrombolytic therapy, ... appraisal involves determining the validity of the study design, understanding the results and decidingwhether and how the results may be applied in practice. The factors to consider when critically ... clinicians to insert the devices.Conclusion The potential benefits of careful use of IABP therapy areunlikely to be offset by vascular and hemorrhagiccomplications. In the final analysis of...
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Báo cáo y học: " Science review: Key inflammatory and stress pathways in critical illness – the central role of the Toll-like receptors" ppsx
... occur in the setting of infection, and it is possible that the primary geneticlesions in autoimmunity involve components of the samesystem that induces cytokine production in the course of aninfection. ... creates the septic syndrome, and a handful of specific receptors alert the host to the presence of aninfection. The effector limb of the responseDuring the decade of the 1980s, one of the key discoveries ... observed in septic shock. In part, they do so bytriggering the release of many secondary cytokines, includ-ing IL-6, and numerous chemokines, which may further con-tribute to the septic syndrome.It...
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Báo cáo y học: "Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: κ role for nuclear factor-κ" pdf
... infiltration into the lungs and to increased pulmonary proinflammatory cytokine expression [7].However, the initial events induced by hyperoxia, therebyleading to acute inflammatory lung injury, remain ... phosphorylation.Anti-inflammatory cytokine-mediated oxidant injuryAnother anti-inflammatory cytokine that is involved as a reg-ulatory element in lung injury is IL-11. For instance, the role of ... proinflammatorysequence induced by hyperoxia. Increased expression of pro-inflammatory cytokines therefore appears to be an importantfactor contributing to the development of acute lung injury.Another...
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