Báo cáo y học: "Bench-to-bedside review: Bacterial virulence and subversion of host defence" pps

... array of specific mechanisms that confer virulence and the capacity to avoid host defence mecha- nisms. Mechanisms of virulence are often mediated by the sub- version of normal aspects of host ... [25]. Yersinia sp. utilise a T3SS to directly inoculate effector proteins into the cytoplasm of host phagocytic cells. These effector proteins, including YopH, YopE, and YopT...

Ngày tải lên: 13/08/2014, 11:23

... membrane [45]. Binding of guanine nucleotides and hydrolysis of GTP by GST±Rab31 and GST±Rab32 Many studies have shown that bacterially expressed R ab proteins, devoid of post-translational modi®cations, ... lg of platelet protein and 0.5 lg of GST and GST±Rab p roteins; (B) an [a- 32 P]GTP overlay [17] of a nitrocellulose blot of a gel containing 40 lg of platelet pro...

Ngày tải lên: 08/03/2014, 16:20

... end of the inspiratory limb of the ventilatory circuit. The flow i s constant, varying between 50 and 2000 ml/min. The concentration in the cylinder can vary fr om 225-2000 ppm. Users of this sys- tem ... article as: Puybasset and Rouby: Equipment review: Pulmonary uptake and modes of administration of inhaled nitric oxide in mechanically-ventilated patients. Critical Care 1...

Ngày tải lên: 12/08/2014, 18:20

... center, Institute of Microbiology and Epidemiology, Academy of Military Medical Science, China; c Jing a. Department of Microbiology, Third Military Medical University, China; d Bacterial culture ... mechanisms of adsorption and the host ranges of different phages may allow genetic manipulation to alter the phage host bind- ing profile artificially. To gain a better unders...

Ngày tải lên: 12/08/2014, 01:22

... analyzed the data, and wrote the manuscript. RG conceived of the study, performed the design and coordination of the study, analyzed the data, and revised the manuscript. HF, MY, SB, NB, and ... Serology was determined for Ct-IgG antibodies by Micro Immunofluorescence assay as described by Wang and Grayston [29]. b Serology was determined for Ct-IgA antibodies by ELISA (Labsy...

Ngày tải lên: 09/08/2014, 14:22

... are a useful way of describing both qualitative and grouped quantitative data and there are also many types of graph that provide a convenient summary. Qualitative data are commonly described using ... between 7.0 and 7.9 g/dl, and so on). These categories can be defined in any way and need not necessarily be of the same width, although it is generally more convenient to have...

Ngày tải lên: 12/08/2014, 18:21

... is defined entirely by its mean and SD, the following rules (rep- resented by parts a–c of Fig. 4) will always apply regardless of the specific values of these quantities: (a) 68.3% of the distribution ... entirely by its mean and standard deviation (SD), the following rules apply: (a) 68.3% of the distribution falls within 1 SD of the mean (i.e. between mean – SD and mean +...

Ngày tải lên: 12/08/2014, 18:21

... active phagocytes, and are quite capable of Review Science review: Key inflammatory and stress pathways in critical illness – the central role of the Toll-like receptors Bruce Beutler Professor, ... the septic syndrome, and a handful of specific receptors alert the host to the presence of an infection. The effector limb of the response During the decade of the 1980s, one...

Ngày tải lên: 12/08/2014, 19:21

Ngày tải lên: 12/08/2014, 19:22

... regulation of NO release and synthesis has been found to be significantly effected by pH o both in vitro and in vivo, and may be partially responsible for acidosis-associated hemodynamic instability. ... of stay [47]. Because metabolic acidosis is both commonly caused and treated by clinicians, an understanding of the physiologic consequences of altered pH o is imperative. Sec...

Ngày tải lên: 12/08/2014, 20:20