... after having
recruited 6,100 patients [5].
Third, further aggravating the problem of power, the study
turned out to realize intensive insulin therapy, but without tight
glycaemic control. The median ... Bouillon
R: Intensive insulin therapy in the medical ICU. N Engl J Med
2006, 354:449-461.
4. Krinsley JS: Effect of an intensive glucose management proto-
col on the m...
... and in the conception of the study. GH participated in the
conception of the study. DG conceived the study, participated in its design
and in the article redaction. AMR conceived the study, participated ... conceived the study, participated in its design and in acquisition of data,
coordinated the study and wrote the article. AD participated in the de...
... the intensive insulin group
who received the conventional insulin protocol. According to
the intention-to-treat principle, they were analysed in the group
they had been assigned to originally. ... were
enrolled. The 28-day mortality rate was 32.4% (81 of 250) in the
standard insulin therapy group and 36.6% (93 of 254) in the
intensive insulin therapy group (Relativ...
... approximately 10%
of the variability in tight glycaemic control. BMI and APACHE II
score explained most (27%) of the variability in tight glycaemic
control in the multivariate analysis, after adjusting ... on the basis of controlling nutritional intake in
addition to insulin [12,13]. In a pilot study of 19 patients, they
reported that 62% of measurements (ta...
... decreased
mortality in surgical intensive care patients in association with
tight glycaemic control (TGC), based on intensive insulin
therapy. However, two negative studies were recently
reported, which were interrupted ... early because of high rates
of severe hypoglycaemia, namely the VISEP study [5] and the
as yet unpublished Glucontrol trial. Hence, there is currentl...
... frequency
of blood glucose monitoring, variability in the accuracy
of glucometer devices used, variability in the methods
used to defi ne euglycemia, whether insulin dosing was
driven by paper ... using
intensive insulin [5-10].
e main advantages of SPRINT are that the protocol
aims for relatively strict euglycemia, the protocol is con-
ser vative in application, th...
... care facility and intensive care unit length of stay by ageDischarge to rehabilitation or long-term care facility and intensive care unit (ICU) length of stay by age category from the Australian ... elderly patients requiring intensive care.
JAMA 1993, 269:3119-3123.
8. Chelluri L, Pinsky MR, Grenvik AN: Outcome of intensive care of
the 'oldest-old' c...
... calculated by divid-
ing the systolic pressure in the injured limb by the systolic
pressure in the uninjured limb. This tool has been vali-
dated in the setting of penetrating and blunt extremity
injuries ... misleading API
of 1.1, suggesting the absence of an arterial injury. In
recent years, CT-angiography (CT-A) has come to play an
increasing role in diagnosing...
... immunosuppression and the recently per-
formed surgery may be the causes of the infective
endocarditis.
Conclusions
To the best of our knowledge, we describe the first case
of Mluteusendocarditis involving a ... gentamicin was discontinued nine days later and
replaced by 600 mg of rifampicin, After t wo weeks of
vancomycin and rifampicin treatment our patient was
still feb...