... Murata N,Shiozawa S, Matsubara T, Yamana S, Matsuda T: Intra-articularinjection of hyaluronate (SI-6601D) improves joint pain and synovial fluid prostaglandin E2 levels in rheumatoid arthritis: ... jointcavity, and maintaining overall joint homeostasis by inhibitingphagocytosis, chemotaxis, scar formation, and angiogenesis[10,11].Proinflammatory cytokines, free radicals, and proteinasesfound ... 1Research article Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cellsKelly S Santangelo1, Amanda L Johnson1, Amy S Ruppert2 and Alicia L Bertone11Department...