Báo cáo y học: " Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension" ppt

... nervous system. Conclusions In animals with acute pulmonary hypertension, inhaled iloprost improved global haemodynamics primarily via selective pulmonary vasodilatation and restoration of left ventricular ... contractility in animals with and without blockade of the ANSThe effects of inhaled iloprost on RV afterload and contractility in animals with and...

Ngày tải lên: 13/08/2014, 11:22

... Murata N, Shiozawa S, Matsubara T, Yamana S, Matsuda T: Intra-articular injection of hyaluronate (SI-6601D) improves joint pain and synovial fluid prostaglandin E 2 levels in rheumatoid arthritis: ... joint cavity, and maintaining overall joint homeostasis by inhibiting phagocytosis, chemotaxis, scar formation, and angiogenesis [10,11]. Proinflammatory cytokines, free radicals, an...

Ngày tải lên: 09/08/2014, 08:23

... media- tors and a direct action on platelets via the a2 a receptor [25]. In a similar way, under stress conditions ATP and ADP act in combination with epinephrine and n orepi- nephrine and thus can ... endocrine interactions and their regulation by feeding, stress and energetic demands [22]. In this context, stress may deregulate the circadian timing present in the...

Ngày tải lên: 10/08/2014, 09:20

... sterile conditions, a median abdominal incision was made and the peritoneum was slit to expose the abdominal aorta. Finally the abdominal aorta was banded with the sup- port of a hard catheter of 1.6 ... weight and thickness, (2) Hematoxylin and Eosin (H&E) staining outlining hypertrophic myocyte morphology and alteration of intercalated disk structure (disruption and...

Ngày tải lên: 10/08/2014, 09:21

... revealed that there was a dose dependent reduction of plasma amylase (Fig. 1), pancreatic inflammation as evidenced by pancreas MPO and histology (Fig. 2A and 2B) and pulmonary inflamma- tion, as ... differential regulation of inflammatory responses mediated by NaHS in pancreas and lung. Conclusions In conclusion in this study of acute pancreatitis induced by hourly...

Ngày tải lên: 11/08/2014, 08:22

... Rabbit monoclonal antibodies against human Smad2 and Smad3, and phosphorylated Smad2 and Smad3 were from Cell Signaling Technology (Beverly, MA). Sheep HRP-conjugated polyclonal anti- mouse and ... TGF-b 1on cadherin expressi on were analysed by one-way ANOVA on raw densitometric data normalised for b -actin as loading control. The effects of PPARg ligands in the pre- sence...

Ngày tải lên: 12/08/2014, 11:20

... 0.01 Morphometry of pulmonary arteryFigure 2 Morphometry of pulmonary artery. Hematoxylin-eosin stained sections of main pulmonary artery (upper panels) and aorta (lower panels) from control (A and C) and ... the analysis of the data and in the preparation of the manu- script. VIP was involved in the conception of the study, participated in its design and...

Ngày tải lên: 12/08/2014, 14:20

... manuscript. AS participated in the study design and in the analysis and interpretation of the data and helped to draft the manuscript. FD participated in data acquisition, analysis, and interpretation and ... the acquisition, analysis, and interpretation of data and drafted the manuscript. LK participated in the study design and in the acquisition and analysis...

Ngày tải lên: 12/08/2014, 15:22

... and cilia [4]. Diuretics with an action on ionic channels present in the airway epithelium can alter ionic movement and change the physical properties and transportability of mucus. For instance, ... is caused by a new class of drugs that can change MCT. For instance, inhalation of amiloride increases MCT in patients with cystic fibrosis by inhibiting the active absorpti...

Ngày tải lên: 12/08/2014, 18:21

... defence and play a significant role in airway inflam- mation by releasing NO, a potentially important mediator of airway inflammation [13,14], as well as releasing other mediators and recruiting inflammatory ... prostaglandins and a variety of cytokines [7]. In the lungs and skin of smokers mast cells increase in absolute numbers and smoking may be associated with...

Ngày tải lên: 12/08/2014, 18:22