Báo cáo y học: " Guidance in sepsis management: navigating uncharted water" potx

... have Letter Guidance in sepsis management: navigating uncharted waters? Michael C Reade 1 , Stephen J Warrillow 1 , John A Myburgh 2 and Rinaldo Bellomo 1 1 Department of Intensive Care Medicine, Austin ... Normoglycaemia in Intensive care Evaluation and Survival Using Glucose Algorithm; SSC = Surviving Sepsis Campaign; VISEP = Efficacy of Volume Substitution and Insulin thera...

Ngày tải lên: 13/08/2014, 11:22

... be explained in several ways. First, the interventions do not affect outcome. Certainly, there is mounting evidence that some of the studied interventions, such as application of the pulmonary artery ... outcome. Second, any beneficial effects are offset by unwanted side effects. For example, better titration of care secondary to information gained by pulmonary artery catheter use may be of...

Ngày tải lên: 12/08/2014, 19:22

... S, Pugin J, Pinsky M, Radermacher P, Richard C: Year in review in Intensive Care Medicine, 2006. I. Experimental studies. Clinical studies: brain injury, renal fail- ure and endocrinology. Intensive ... currently employed in one third of our surveyed hospitals. In addition, pain monitoring is increas- ingly performed. Chanques and colleagues [9] have pointed out that by monitoring and...

Ngày tải lên: 13/08/2014, 10:20

... purposes) tional study is the only way in which we can evaluate the poten- tial independent mortality effects of sepsis- induced versus non -sepsis- induced ALI in humans. In this prospective study, we adjusted ... mortality, specifically adjusting for differences in severity of illness using three different ICU measures which were not colinear, and all remained statistically associa...

Ngày tải lên: 13/08/2014, 19:20

... obvious choice as sepsis markers, since cytokines are key mediators of the in ammatory response to sepsis. Leptin, a hormone mainly generated by adipocytes, acts centrally in the hypothalamus ... however, the interest in leptin as a sepsis marker waned. Leptin, a hormone mainly generated by adipocytes, acts centrally in the hypothalamus to regulate body weight and energy exp...

Ngày tải lên: 13/08/2014, 20:21

... is being directed towards the role of cytokines and signalling pathways in the regulation of the MMPs in disease. Blocking of certain cytokines or inhibiting the inflammatory cell signalling path- ways ... the cytokine signalling pathways [130]. Finally, there is interest in the synthesis of modified TIMPs that are specifically targeted to inhibit specific enzymes [131–133]. It is inter...

Ngày tải lên: 09/08/2014, 01:21

... from leukocytes can play a role in inflammatory arthritis by inducing the synthesis of MMPs, chemokines and cytokines in SF [11,12]. It could also be shown that, in particular, the synthesis of ... discovered ‘novel’ cytokines are also involved in promoting joint inflammation in RA. For example, IL-32, which is intensively expressed in RA synovial tissue, resulted in joint infla...

Ngày tải lên: 09/08/2014, 10:20

... Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. Mol Cell 2000, 5:949-957. 61. Chan RC, Black DL: The polypyrimidine tract ... of the AS event in the mouse. Many essen- tial liver metabolic and detoxifying enzyme-coding genes appear on this list, including enzymes involved in sugar R74.6 Genome Biology 2004,...

Ngày tải lên: 14/08/2014, 14:21

Ngày tải lên: 08/08/2014, 18:20

... Rhinosinusitis Recurrent acute rhinosinusitis Chronic purulent rhinosinusitis Chronic hyperplastic rhinosinusitis Chronic rhinosinusitis with polyposis Samter’s triad 3 Allergic fungal rhinosinusitis 4 Eosinophilic ... (chronic hyperplastic rhinosinusitis) but without polypo- sis and those patients with diffuse sinonasal polyposis with polyps projecting into or com- pletely occluding the nasa...

Ngày tải lên: 08/08/2014, 20:23