Báo cáo y học: "Myocardial protection in sepsis" potx

... RA-induced and RA therapy-induced hyperhomocysteinemia to CHF risk in RA has yet to be completely elucidated. Inflammatory cytokines In patients with overt CHF, levels of inflammatory cytokines (TNF-α, ... progressively failing myocardium) fashion, contributing to subclinical and eventually clinically recognizable ventricular dysfunction (Fig. 1). Inflammatory pathways and myocard...

Ngày tải lên: 09/08/2014, 07:20

... following collagen antibody-induced arthritis inductionReduced severity of arthritis in poly(ADP-ribose) polymerase (PARP)-1 deficient mice and PARP-1 sufficient mice following collagen antibody- induced ... induced to a similar extend in Figure 4 Representative hematoxylin-eosin stained sections of knee joints in mice with collagen antibody-induced arthritis (CAIA)R...

Ngày tải lên: 09/08/2014, 07:20

... the European Society of Cardiology, 2011. 12(5): p. 372-4. Page 1 of 10 Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device Lars ... acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Myocardial recovery in peri-partum cardiomyopathy after continuous flow...

Ngày tải lên: 10/08/2014, 09:22

... Schoendube Abstract Background: Hemodynamic function may be depressed in the early postoperative stages after cardiac surgery. The aim of this study was the analysis of the myocardial contractility in neonates after cardiopulmonary ... function in survived neonatal piglets remained stable 6 hours after cardiopulmonary bypass and mild hypothermia probably due to regio...

Ngày tải lên: 10/08/2014, 09:22

... basic research. The potential key role of proteins that were originally believed to be exclusively involved in coagulation in the inflammatory response provides an exciting potential mechanism(s) ... augmenting or inhibiting the contribution of the clotting cascade components to inflammation would be required for determining the selection and dosing of potential new therapies. Alter...

Ngày tải lên: 12/08/2014, 19:21

... as current events, namely bombings and shootings, with bodily injury the most likely result. In fact, a state-wide system has already been implemented on this principle in Connecticut, using the state-wide ... terrorist bombing disasters, and lends itself to quality improvement analysis. The authors should be commended for applying the established objective measures of injury severity (...

Ngày tải lên: 12/08/2014, 20:20

... Another of the stated goals of the Campaign, and one that directly addresses an issue identified by the survey, is to raise public awareness of sepsis as a common and deadly disease in critically ill ... management through the implementation of guidelines to create a global standard of care for sepsis, thereby reducing mortality from sepsis by 25% over 5 years. An unprecedented 11 o...

Ngày tải lên: 12/08/2014, 20:20

... of inflammatory mediators on the brain. Investigations addressing SAD will remain difficult due to the problem of correctly identifying and quantifying this entity. The value of monitoring cerebral ... one could speculate that, in analogy to traumatic brain injury, severe brain dysfunction is necessary to disturb CO 2 reactivity. The action of inflammatory mediators on the endothelium h...

Ngày tải lên: 13/08/2014, 08:21

... injury? The interpretation of S-100β, a protein found predominately in astrocytes and Schwann cells, is difficult. Even when an increase in S-100β is not due to extracranial sources, includ- ing the ... PN, Shatney CH, Schein RM, Wilson MF, Sheagren JN, Hinshaw LB: Impact of encephalopathy on mor- tality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Stu...

Ngày tải lên: 13/08/2014, 11:22

... myocardial infarction were reduced. Hypotension was very instrumental in causing the adverse events. Interestingly, sepsis and infection were also clearly more common on metoprolol. Commentary Myocardial ... offset by an increase in cardiogenic shock (11 per 1,000) [7]. This was most prominent in the first day of therapy in elderly patients with tachycardia and low blood pressure, a p...

Ngày tải lên: 13/08/2014, 11:22

... limits acetylcholine production by the vagus nerve during sepsis. Since vagus nerve stimulation requires α 7 -nicotinic acetyl- choline receptors, direct activation of this receptor using nicotinic ... these studies, inhibition of NF-κB after partial hepatectomy results in massive hepatocyte apoptosis and impairs liver function. Conversely, NF-κB activation in the liver prevents hepatic i...

Ngày tải lên: 13/08/2014, 16:20

... exacerbate liver injury [9]. In addition to apoptosis, certain caspases, such as caspase-1, are involved in cytokine maturation by proteolytically proces- sing the inactive precursors of interleukin ... not apoptotic cells, is systemically elevated in human sepsis and functions as a mediator of endotoxin lethality in mice [12]. Intense research has recently delineated the sign...

Ngày tải lên: 13/08/2014, 18:22

... cerebral perfusion on brain function in sepsis. Sepsis and the brain In sepsis, the brain may be aff ected by many systemic disturbances, such as hypotension, hypoxemia, hyper- glycemia, hypoglycemia, ... brain and regulates brain capillary blood fl ow [1]. In sepsis, cerebral endothelial cells are activated by lipopoly- saccharide (LPS) and pro -in ammatory cytokines, including bra...

Ngày tải lên: 13/08/2014, 20:21

... severe sepsis and septic shock, the number of signifi cant diff erences in terms of the number of circulating NK cells, CD4 + T lymphocytes, CD8 + T lymphocytes, and B lymphocytes was limited ... Kranidioti H, Lignos M, Louis K, et al.: Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. Cri...

Ngày tải lên: 13/08/2014, 20:22

... maize genome. In this preliminary analysis of the draft genome sequence by Josh Stein (MGSC, Cold Spring Harbor Laboratory, Cold Spring Harbor, USA) it is clear that just the gypsy family huck element ... The main story is gene loss (http://www.maizesequence.org). Within a duplicated 22-Mb contig analyzed in detail by Wei and colleagues, maize has typically retained only one gene copy...

Ngày tải lên: 14/08/2014, 08:21