... N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I: The N-terminal domain of thrombomodulin sequesters high -mobility group- B1 protein, a novel antiinflammatory mechanism. ... monocyte/macro- phages both can respond to inflammatory agents to trans- locate HMGB1 and can be activated by HMGB1 to release proinflammatory cytokines. The role of HMGB1...
Ngày tải lên: 09/08/2014, 10:23
... HMGB1+LPS 0 2000 4000 6000 8000 HMGB1 (4 g/ml): LPS (100 ng/ml): Detoxified LPS (10 g/ml): IL-8 IL-6 - - - + - - - + - + + - - - + + - + - + + + + + - - - + - - - + - + + - - - + + - + - + + + + + * ** * *** pg/ml Figure ... IL-6 - - - + - - - + - + + - - - + + - + -...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo y học: "High mobility group box-1 protein - one step closer to the clinic" docx
... late-acting inflam- matory mediator high mobility group box 1. Am J Pathol 2008, 172:129 7-1 307. 12. Hatada T, Wada H, Nobori T, Okabayashi K, Maruyama K, Abe Y, Uemoto S, Yamada S, Maruyama I: Plasma ... research, which, step by step, will hopefully yield greater insight into the complex biology of this interesting molecule. Finally, it should be emphasized that although HMGB1...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: "High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis" potx
... HMGB-1: High Mobility Group Box Protein- 1 Figure 1 High Mobility Group Box Protein- 1 (HMGB-1) by category of groups. Figure 2 Receiver operating characteristic (ROC) curve of Hig h Mobility Group ... HMGB-1 also induces the production of proinflammatory cytokines such as TNF, interleukin (IL )-1 a and -1 b, IL6 and macrophage inflam- matory protein 1 (MIP1) [10,14,16]...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis." ppsx
... O, Erlandsson-Harris H, Janson A, Kokkola R, Zhang M, Yang H, Tracey KJ: High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000, 192:56 5-5 70. 9. ... [7]. Systemic administration of either neutralizing HMGB1 antigen-affinity purified polyclonal anti- bodies or the anti-inflammatory domain of HMGB1, termed the A-box...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo khoa học: "High mobility group box-1 protein in patients with suspected community-acquired infections and sepsis: a prospective study" pot
... diagnosis and therapy. High mobility group box-1 protein (HMGB1) has been known for many years as a nuclear chromosomal protein. Its role as a pro-inflammatory cytokine in sepsis and rheumatoid arthritis ... difference between the infected and the non-infected patients. Levels of HMGB1 correlated only very weakly to other pro-inflammatory markers and did not correlate to the...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo Y học: High pressure-induced changes of biological membrane Study on the membrane-bound Na+/K+-ATPase as a model system pdf
... 1-palmitoyl-2-oleoyl-sn -glycero-3-phospho- choline increases by 15% from 63.2 to 72.3 A Ê [43] and the cross-sectional area occupied by hydrocarbon chains of 1, 2- dipalmitoyl-sn-glycero-3-phosphocholine bilayer ... Mg 2+ and f orms ADP-sensitive phospho- enzyme followe d by releasing Na + to form the K + -sensitive phospho-enzyme. This is dephosphorylated to form the K + -bou...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo y học: " High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life" pdf
... drawn at the time of recruitment to the original cross-sectional study was stored at -8 0°C until assayed. The study was approved by the Southern Health Human Research and Ethics Committee and the ... carti- lage volume suggests the possibility that the presence of sub- clinical systemic inflammation has a role in the early stages of the disease process that precedes sy...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " High recombination rates and hotspots in a Plasmodium falciparum genetic cross" docx
... 3). Our mSFPs therefore greatly improve the cover- age of genetic markers across the 14 chromosomes. To further verify the genotype calls and clarify the mismatches, we re-typed the 19 MSs that ... differentiates into male and female sexual stages - termed gametocytes - that circulate in the bloodstream. When the gametocytes are taken up by a feeding mosquito during a...
Ngày tải lên: 09/08/2014, 22:24
Báo cáo y học: " Human Polycomb group EED protein negatively affects HIV-1 assembly and release" pot
... Rakotobe - dinaraktb@yahoo.fr; Jean-Claude Tardy - jean-claude.tardy@chu-lyon.fr; Patrice André - patrice.andre@chu-lyon.fr; Saw See Hong - sawsee.hong@sante.univ-lyon1.fr; Jean-Luc Darlix - jldarlix@ens-lyon.fr; ... copy no./ml (f) (g) 72 - 55 - - EED + EED Virus + anti-VSV-G Ab m - VSV-G 43 - 24 - -CAp24 load : 10 50 μl + anti-Gag Ab Virus + anti-N...
Ngày tải lên: 13/08/2014, 05:22