Báo cáo y học: "Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome" ppsx

... natural history of the systemic inflammatory Key messages • The -1377delA promoter polymorphism was signifi- cantly associated with increased risk of delayed mortal- ity in patients with SIRS. • ... phenotype effect of the HMGB1 polymorphism on the HMGB1 serum concentration may only become apparent in disease settings. The finding of lower HMGB1 levels in patien...

Ngày tải lên: 13/08/2014, 11:22

... by silver staining on polyacrylamid gel. Statistical Analysis Allele frequencies were determined by gene counting and compared using the א² test. The data was analysed using SPSS 12.0 software. ... characterized by a rise of HDL and lowering of LDL, triglycerides, and insulin [5]. In addition, transgenic expression of an activated PPARδ in mice conferred resistance to obesity a...

Ngày tải lên: 31/10/2012, 17:03

... down- regulation of phagocyte activity may be involved in the mechanism of action of anti-TNF-α therapy [9]. BSA = bovine serum albumin; C3Zy = C3-coated zymosan; FMLP = N-formyl-methionyl-leucyl-phenylalanine; ... second aim of the study was to determine whether downregulation of phagocyte activities are involved in the anti -inflammatory activity of anti-TNF-α therapy. The...

Ngày tải lên: 09/08/2014, 06:22

... is properly cited. Abstract Introduction The purpose of the present study was to systematically review the effect of cyclophosphamide treatment on pulmonary function in patients with systemic sclerosis ... available data, CYC treatment in patients with SSc- related ILD does not appear to result in clinically significant improvement of pulmonary function. Since none of...

Ngày tải lên: 09/08/2014, 13:22

... immune recovery, suggesting the hypothesis of apathogeneticroleplayed by HIV-1 infection in the liver damage. In patients with HIV-1 disease there are a few data on liver injury not related to hepatotropic ... pre- dominantly within the normal ranges, with only small increases due to occasional alcohol in take. On Septem- ber 2006, during a rescue treatment with atazanavir/ ri...

Ngày tải lên: 10/08/2014, 05:22

... endothelium and synthesis of other pro -inflammatory cytokines such as IL-1 and IL-6. Similar to results regarding pro -inflammatory cytokines, high levels of anti -inflammatory cytokines (IL-10 and TGF-b) ... 8:23 http://www.journal-inflammation.com/content/8/1/23 Page 7 of 7 Plasma levels of pro and anti -inflammatory cytokines Plasma levels of IL-6, TNF-a and IFN-g were signi...

Ngày tải lên: 11/08/2014, 03:20

... previously reported in patients with bipolar I or II depression receiving quetiapine or in patients with bipolar I depression receiving olanzapine/ fluoxetine [21-23]. They are also within the range of values ... analysis. The efficacy of asenapine in treating depressive symp- toms is supported by in vitro and in vivo precli nical findings. Asenapine has a complex recept...

Ngày tải lên: 11/08/2014, 15:22

... limits the possibility of collecting histological evidence of IPA. In a recent study with the largest series of IPA in patients with chronic obstructive pulmonary disease, none of the 53 cases ... Treatment of Cancer/National Institute of Allergy and Infectious Diseases Mycoses Study Group; IBPA, invasive bronchial- pulmonary aspergillosis; IPA, invasive pulmonary a...

Ngày tải lên: 14/08/2014, 08:21

... before transferring to our hospital. In our study, the length of stay for patients in pleural empyema was 24.8 days and the length of stay after surgery was 17.5 days. The length of stay was longer ... antibiotics may result from delaying diagnosis of empyema or lung abscess. There are many patients with low respiratory infection comp li- cated with pleural empyema. The di...

Ngày tải lên: 10/08/2014, 09:22

... Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study 5. PLoS ONE 2008, 3:e1948. 17. Olerup O, Zetterquist H: HLA-DR typing by PCR ... MAF = minor allele frequency; Ref = reference; SNP = single nucleotide polymorphism. a combination of initial finding and replication (when available) in the cited study;...

Ngày tải lên: 09/08/2014, 14:20