... otypic analysis (at the p rotein level), the f ew animals yielding in their milk the a s1 -CasM variant were exclusively heterozygous M/F a t the a s1 -Cas locus. There- fore, analysis o f their ... secondly impairs the phosphorylation of Ser64 in the M variant. The sequence determined is consistent with the molecular mass measured for the native protein. The phosp...
Ngày tải lên: 22/02/2014, 04:20
... phase of inflammatory arthritis [27,28]. Since the pro-apoptotic pro- tein Bid links the extrinsic to the intrinsic pathway, we exam- ined the affect of inducing experimental inflammatory arthritis in ... & Therapy Vol 9 No 3 Scatizzi et al. Page 4 of 10 (page number not for citation purposes) invasion of leukocytes, proliferation of synoviocytes resulting in the...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Adherence with urate-lowering therapies for the treatment of gout" pps
... was involved in the analysis of data from this study and interpretation and presentation of results. RY was involved in the interpretation of the data, and drafting of this article. IO was involved ... adherence to newly-initiated ULDs was common in gout patients, with only 44% of the study pop- ulation achieving an MPR > 0.80 in the first year of therapy. Pre...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: " Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder" pps
... University Medical Centre, Mainz, Germany. 3 Clinic for Psychiatry and Psychotherapy, Katzenelnbogen, Germany. 4 Clinic for Psychiatry and Psychotherapy, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Germany. Authors’ ... role in the currently ongoing collection of data. Author details 1 Department of Psychiatry and Psychotherapy, University Medical Centre, Mainz, Germany. 2 Interdiscipl...
Ngày tải lên: 11/08/2014, 16:23
Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps
... routine marker of infection in this specific setting. Competing interests The author(s) declare that they have no competing interests. Author's contributions JF initiated the project and is the principal ... according to the day's randomization status; antibiotic free days following the 4 days after any microbiological work up; and antibiotic free days during the wee...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"
... osteosynthesis [4]. The major advantages of a hip spacer implantation are: (i) immediate treatment of the infection source by locally reaching high antibiotic levels, (ii) maintance of joint ... Generally, the surgical treatment of these fractures should be planned taking into consideration any further surgical revisions or the later prosthesis reimplantation. If possible...
Ngày tải lên: 26/10/2012, 09:53
Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc
... 2002 understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nes involved in the biosynthetic pathway c an certainly provide valuable information. In ... addition of Tween 40 [39], i t can be concluded that the 482 Gly residue is important for the activity of the enzyme, likely being one of the resid...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "What do biomarkers tell us about the pathogenesis of ankylosing spondylitis" ppsx
... MRI examination even shows that while inflammatory changes in the spine predict the development of new syndesmophytes, complete resolution of inflammation at a vertebral corner following the institution ... pathogenesis of ankylosing spondylitis? Walter P Maksymowych Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2S2 Canada Corresponding author: Walter...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: " Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations." ppsx
... 8:12 http://www.aidsrestherapy.com/content/8/1/12 Page 6 of 10 -75°C depending on the melting point of the gelling agent. Additional excipient (Vitamin E, Vitamin E Acetate, Butylated hydroxyanisole or Butylated hydro- xytoluene) ... textural properties of polymer gels composed of poly (methylvinylether-co-maleic anhydride) and poly(vinylpyrrolidone): Rheological and mathematical...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: " Intermittent long-wavelength red light increases the period of daily locomotor activity in mice" ppsx
... period-lengthening effects of red light than of full-spectrum light. Another possibility is that the shape of the τRC differs between the two strains, so that for C57BL/6 mice more of the period- lengthening ... tape. Assessment of circadian period of locomotor activity Activity events were grouped into 5-minute bins by the Stanford Chronobiology Systems' (Stanfor...
Ngày tải lên: 10/08/2014, 09:20