... [18]. They provided data on placebo and on 5, 10, 30 and 60 mg doses of etoricoxib. The trial was dou-ble blind and randomised, and included patients with radio-graphic and clinical diagnosis of ... duloxetine [17], and about half with higherdoses of pregabalin [16]. Proportions were even lower in breakthrough pain treatment [16]. In acute pain trials in stand-ardised pain models, commonly ... A, van Ingen H, Brabant T, Fort JG, for the CelecoxibRofecoxib Efficacy and Safety in Comorbidities Evaluation Trial(CRESCENT) Investigators: The effects of cyclooxygenase-2inhibitors and nonsteroidal...