Báo cáo y học: "Cost-effectiveness analysis for joint pain treatment in patients with osteoarthritis treated at the Instituto Mexicano del Seguro Social (IMSS): Comparison of nonsteroidal anti-inflammatory drugs (NSAIDs) vs cyclooxygenase-2 selective inh
Báo cáo y học: "Cost-effectiveness analysis for joint pain treatment in patients with osteoarthritis treated at the Instituto Mexicano del Seguro Social (IMSS): Comparison of nonsteroidal anti-inflammatory drugs (NSAIDs) vs. cyclooxygenase-2 selective inh
... with osteoarthritis treated at the Instituto Mexicano del Seguro Social (IMSS): Comparison of nonsteroidal anti-inflammatory drugs (NSAIDs) vs. cyclooxygenase-2 selective inhibitorsIris Contreras-Hernández1, ... simplify the clinical reality observed in patients with OA treated with alternatives compared with the treat-ment of joint pain at the IMSS. The proposed modelaimed to identify the probability to ... pharmacological treatment for the control of joint pain secondary to OA of the knee and/orhip in patients treated at the IMSS.MethodsDecision Tree Model The study constructed an analytical model that may...
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Báo cáo y học: "Persistence and compliance to antidepressant treatment in patients with depression: A chart review" doc
... a minority of patients in routine clinical practice in terms of psychopathology [10]. In addition, this study did not evaluate effects of clinicalcharacteristics and other antidepressant drugs ... persistencerate in the beginning of the treatment. While a causal attri-bution cannot be made in light of the retrospective nature of this study, the results highlight the critical importance of devising ... antidepressant treatment for 6 months. Among 252 patients who discontinued their initial antidepressant, 63.1% of these patients did so withoutconsulting their physicians. Sertraline use was associated with...
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Báo cáo y học: "Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial" potx
... new-onset treatment. In our patients, usual treatment was pursued. The fact that our patients were treated with analgesics and NSAIDs at baselinemay also explain the relative modesty of the baseline ... years of age, and could demonstrate their capacity tofill a diary relating their daily treatment. Patients with inflammatory arthritis, with osteoarthritis notaffecting the knees or hips, with ... period. The study drug was used in addition tothese medications. Patients were told that they could reduce the use of their pain and inflammation medication if they didnot feel the need for them,...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... one-half of the patients were treated with intrave-nous CYC [12]. We analyzed the two cohorts of patients in this study separately. In addition, in this study the FVC and the DLCO were assessed in ... understand the role of CYC in the care of these patients. In our meta -analysis, two of the three greatest mean differences of the FVC after 12months of therapy were achieved in observational studiesusing ... available data, CYC treatment in patients with SSc-related ILD does not appear to result in clinically significantimprovement of pulmonary function. Since none of the patients included in these...
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Báo cáo y học: " Relationships among neurocognition, symptoms and functioning in patients with schizophrenia: a path-analytic approach for associations at baseline and following 24 weeks of antipsychotic drug therapy" ppt
... functioning in patients with schizophrenia. This post-hoc analysis evaluates the relationships among cognition, psychopathology, and psychosocial functioning in patients with schizophrenia at baseline ... werequalitatively similar to those based on observed data at week 24.While the relationship among variables could vary by treatment, analyzing the data separately by treatment groups would result in ... bestrongly correlated with deficits in psychosocial and occu-pational functioning in patients with schizophrenia [1,2].These earlier reviews of the literature (including a meta- analysis) were...
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Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"
... probably in context of the complex syndrome of malnutrition, inflammation and oxidative stress in patients with CKD. In order to re-duce cardiovascular mortality, nutritional, anti-inflammatory ... in the prediction of car-diac death in dialysis patients. Arch Intern Med. 1988; 148: 2381-2385. 20. Aronow Ws. Usefulness of serum creatinine as a marker for coronary events in elderly patients ... atherosclerosis in patients with kidney failure (38, 40). In some studies the relation between hypoalbu-minemia and CVD is the reflection of inflammation induced malnutrition. The underlying mechanism...
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Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf
... mild heat treatment with the loss of the ability of nucleotides to protect the S1 against thermal denaturation [23]. There is somediscrepancy in the literature about the effect of the N-terminal ... analogs of the S1*ÆATP and S1**ÆADPÆPiinterme-diate states of the S1-catalyzed Mg2+-ATPase reaction [5–7]and, therefore, they are often used for probing the conformational changes occurring in ... obtained by addition of 0.5 mMBeCl2 in the presence of 5 mMNaF. The formation of the complexeswas controlled by measuring the K+-EDTA ATPase activity of the protein. The ATPase activity of...
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Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps
... cells. The second aim of the study was to determine whetherdownregulation of phagocyte activities are involved in the anti-inflammatory activity of anti-TNF-α therapy. The lack of activity on ... observed in patients during adalimu-mab therapy does not explain the decreased influx of neu-trophils into synovial joints previously observed in RA patients during anti-TNF-α therapy [14,15]. ... Inhibition of neutrophil migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized,double-blind...
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Báo cáo y học: "Dermatological conditions during TNF-α-blocking therapy in patients with rheumatoid arthritis: a prospective study" pps
... after treatment with TNF-α-blockingtherapy. Dermatological events led to withdrawal of TNF-α-blocking therapy in 19 patients of 72 patients (26%). The events recorded most frequently were skin infections, ... TNF-α-blocking therapy. 128dermatological events were recorded in 72 patients (25%)during 911 patient-years of follow-up. TNF-α-blocking therapywas stopped in 19 (26%) of these 72 patients because of ... non-Hodgkin lymphoma 2 years later.Discussion The present study is the first large prospective study focusingon dermatological conditions in RA patients on TNF-α-block-ing therapy. Of the patients...
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Báo cáo y học: "Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study" doc
... cells in patients with systemic lupus erythematosus under Rituximab therapyAnalysis of apoptosis of subsets of peripheral blood mononuclear cells in patients with systemic lupus erythematosus ... lymphocytes in the presence of phytohemagglutinin, and cultured for 72 hours. Then, cell proliferation was determined by 3H-methyl-thymidine incorporation. These assays were performed before (day ... erythematosusEffect of Rituximab therapy on different laboratory and clinical parame-ters in patients with systemic lupus erythematosus. Twenty-two sys-temic lupus erythematosus patients with active...
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