... measure the expression of RAGE in the lung tissue and, therefore, wecould not assess the relationship between the membrane-bound and the soluble isoforms of the receptor.Investigating on the dynamics ... N-epsilon-carboxymethyl lysine and S100A12, by ELISA method. In the COPD patients, we assessed the prevalence and severity of emphysema by computed tomography (CT), and the prevalence of chronic cor ... group ifthey had a history of chronic lung disease or atopy, afamily history of COPD, or had had an acute respiratoryinfection in the 4 weeks preceding the study entry.Study protocol The protocol...