Báo cáo y học: " Pain may be inevitable; inadequate management is not" ppt

... probably in vain. Our challenge as a critical care community is to better serve our patients and their outcomes by evaluating and managing pain better. The recent article by Ahlers and colleagues is ... multiple barriers exist that mitigate against the perfect management of pain in the ICU, the first step is to measure the pain and to measure the response to initial therapy. Wit...

Ngày tải lên: 13/08/2014, 10:20

... aneurysm [2,3].  e corner stone of medical therapy for cerebral vasospasm is so-called hyperdynamic therapy. Also referred to as triple-H therapy, this strategy includes the use of hyper- tension, ... perfusion is the mechanism by which hyper- dynamic therapy is purported to exert its benefi cial eff ect, and increases in CBF have been linked to clinical improvement in patients with...

Ngày tải lên: 13/08/2014, 20:22

... pathway in serum not only is determined by mutations in the gene encoding MBL, but also is influenced by promoter polymorphisms. Moreover, biologi- cal activity of MBL also depends on MASP activity ... can directly opsonise pathogens and enhance the activ- ity of phagocytes [12]. Homozygosity for variant MBL alleles is probably a minor risk factor for the presence of SLE, as shown by a...

Ngày tải lên: 09/08/2014, 08:23

... cautionary tale for genetically uncontrolled studies. Background The epidermal growth factor receptor (EGFR) pathway plays key roles in the development and maintenance of many tissue and organ systems ... analyzed the locomotor behaviors in Egfr wa2 mutant mice on genetically defined, congenic backgrounds. Methods: Mice carrying the Egfr wa2 hypomorphic allele were bred to congenicity by ba...

Ngày tải lên: 10/08/2014, 09:20

... glycosylases, is essential for embryonic develop- ment. TDG removes the pyrimidines from G:T or G:U mis- matches that occur by deamination of cytosine or 5-methyl cytosine, respectively. This ... inactivation signal. He discussed a hypothesis, first proposed by Mary Lyon a few years ago, that repression may occur more efficiently on the X chromosome as a result of its high density of LINE...

Ngày tải lên: 14/08/2014, 16:20

... [6]. Pain Although a ubiquitous phenomenon, pain is inherently subjective. The only way to know about someone’s pain is by what they say or show by their behavior. There is an assumption that pain ... to pain. Pain is not an isolated symptom. Severe pain creates fatigue, impairs concentration, compromises mood, degrades sleep, and diminishes overall activity level. For ma...

Ngày tải lên: 09/08/2014, 01:23

... neurofibrillary tangles, a hallmark lesion of the disease. Analysis of clinically normal aged brain tissue revealed systematically less BRCA1, and surprisingly in many cases with ap- parent phosphorylated ... cell cycle markers, re- flecting a re-entry into the cell cycle by affected neurons. However, while such a cell cycle re-entry phenotype is an early and consistent feature of Alzheim...

Ngày tải lên: 26/10/2012, 10:04

... them, and to do his laundry several times a day. His QoL was highly disturbed and his work performance had worsened accordingly (GAF: 50). His disordered thoughts of persecution persisted for several ... severity of psychiatric disturbance. Arch Gen Psychiatry 1976, 33:766-771. 4. Yung AR, Yuen HP, McGorry PD, Phillips LJ, Kelly D, Dell'Olio M, Francey SM, Cosgrave EM, Killackey E,...

Ngày tải lên: 09/08/2014, 01:21

... body fluids as 'biomarkers', where they can now be detected by sensitive immunoassays in accessible fluids such as serum and urine [5-9]. These biomarker assays may be of use in distinguishing ... few years after dis- ease onset [4]. Radiographs only reveal gross anatomical changes. It usually takes at least one year before significant changes in joint damage can be observed...

Ngày tải lên: 09/08/2014, 07:20

... fibroblast-like synoviocytes more than proinflammatory mediators Hyun-Mi Choi 1 , Yeon-Ah Lee 2 , Sang-Hoon Lee 3 , Seung-Jae Hong 2 , Dae-Hyun Hahm 4 , Sang- Yun Choi 5 , Hyung-In Yang 3 , Myung Chul Yoo 1 ... murine chondrocytes [20]. Some questions about this effect may be raised. First, the human recombinant adiponectin protein used in these studies is a single nonglycosylated pol...

Ngày tải lên: 09/08/2014, 14:22