Báo cáo y học: "Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients" pdf

... and integration of clinical findings into decision- making processes. Patients with severe pancreatitis who developed infective necrosis or multiorgan dysfunction showed a sustained increase in ... identified [24], making the point that PCT is better used as a tool to stratify risk in the clinical context than specifically as a binary indicator. A large epidemiological study is r...

Ngày tải lên: 13/08/2014, 10:20

... Australian Intensive Care Foundation. The funding body played no role in study design; in collection, analysis, or interpretation of data; in writing of the manuscript; or in the decision to submit ... the physician was not committed to full supports or they had abodymassindexof40kg/m 2 or greater, allergy to heparin (including any history of heparin-induced throm- bocytopenia), a p...

Ngày tải lên: 13/08/2014, 21:21

... necrosis and apop- tosis, the sepsis is associated with many other forms of cellular stress [14], allowing for active secretion as a potential third mechanism in this scenario. Interestingly, in ... provided the original work is properly cited. Abstract Introduction Risk stratification of severely ill patients remains problematic, resulting in increased interest in potential c...

Ngày tải lên: 12/08/2014, 23:23

... baseline plasma concentrations of cholecystokinin (CCK) (a) and peptide YY (PYY) (b). Figure 3 The relationship between the changes in plasma cholecystokinin (CCK) (a) and peptide YY (PYY) (b) ... occur in up to 50% of critically ill patients and can adversely affect both morbidity and mortality [25,26]. Whilst the mechanisms underlying delayed GE in critical illness remain poorly...

Ngày tải lên: 13/08/2014, 08:21

... functional ability may sometimes be the only way to determine baseline HRQOL. Response shift in critically ill patients Patients become accustomed to their illness. An important mechanism in this adaptive ... measure response shift in critically ill patients. Response shift is important not only in longitudinal observations of HRQOL but also in medical decision making....

Ngày tải lên: 13/08/2014, 11:23

... prospectively collected on a daily basis by senior physicians of the participating ICUs who are clo- sely involved in establishing the database. For all patients, information is recorded at baseline (including ... time-dependent covariates. Yet, this model does not deal with the competing risks issue. This issue arises when more than one endpoint is possible [16]. Typically, “dying i...

Ngày tải lên: 14/08/2014, 08:21

... enough to persist in the airways as the mucociliary elevator would remove all pathogens re- siding within mucus layer of the airways´ lining fluid. As this elevator is driven by the beating of the ... Pseudomonas aeruginosa INTRODUCTION Chronic infection of the airways with P. aerugi- nosa is the leading cause of morbidity and mortality in the majority of CF patients (1). This pa...

Ngày tải lên: 03/11/2012, 11:48

... bed- side; they can only serve as an objective tool in decision making. Although scoring systems may provide an indi- cation of disease severity and prognosis in individual patients and assist in overall ... than one minute per patient per day. The parameters included in any scoring system influence its usefulness in different populations of patients. It is, therefore, perhaps n...

Ngày tải lên: 10/08/2014, 09:23

... be explained by not attaining adequate provision of energy and protein. In the present study we analyze the effects of reaching energy provision guided by indirect calorimetry and provision of at least ... mortality for women who reached both the energy and protein goal, but for men this effect was absent. Discussion Reaching nutritional goals, in this study defined as energy delivery...

Ngày tải lên: 13/08/2014, 18:22

... benefits critically ill patients. Key messages • Demands for ICU beds are increa sing worldwide and delay to ICU admission is becoming a more fre- quent issue. • Thereisanincreaseinmortalityforeachhourof delay ... 44.8%). Analysis of the delay to ICU admission by multivariate analysis is presented in Table 3. Each w aiting hour was associated indepe ndently with a 1.5% increase i...

Ngày tải lên: 14/08/2014, 07:21