Báo cáo y học: "Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients" pdf
Báo cáo y học: "Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients" pdf
... and integration of clinical findings into decision- making processes.Patients with severe pancreatitis who developed infectivenecrosis or multiorgan dysfunction showed a sustainedincrease in ... identified[24], making the point that PCT is better used as a tool tostratify risk in the clinical context than specifically as a binaryindicator. A large epidemiological study is required in intensive ... results! The Danish Procalcitonin Study Group is conducting an RCT of a PCT-guided strategywith mortality endpoints in critically ill patients (NCT00271752)[26]. A French study is looking at another...
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Báo cáo y học: " Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial" potx
... Australian Intensive Care Foundation. Thefunding body played no role in study design; in collection, analysis, orinterpretation of data; in writing of the manuscript; or in the decision tosubmit ... thephysician was not committed to full supports or they hadabodymassindexof40kg/m2or greater, allergy toheparin (including any history of heparin-induced throm-bocytopenia), a pulmonary hemorrhage ... by the administration of any of the following:dop amine, dobutamine, norepinephrine, or epinephrine.Renal failure was defined as a serum creatinine ofgreater than 300 μmol/L or urine output...
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Báo cáo y học: "Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients" pptx
... necrosis and apop-tosis, the sepsis is associated with many other forms of cellularstress [14], allowing for active secretion as a potential thirdmechanism in this scenario.Interestingly, in ... provided the original work is properly cited.AbstractIntroduction Risk stratification of severely ill patients remainsproblematic, resulting in increased interest in potentialcirculating markers, ... resultstakes about 3 hours, making the test a potentially realistic and useful one in the clinical setting (when predicting outcomeearly in the course of a disease process). Finally, we used theSOFA score...
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Báo cáo y học: "The relationship between gastric emptying, plasma cholecystokinin, and peptide YY in critically ill patients" ppt
... baseline plasma concentrations of cholecystokinin (CCK) (a) and peptide YY (PYY) (b).Figure 3The relationship between the changes in plasma cholecystokinin (CCK) (a) and peptide YY (PYY) (b) ... occur in up to 50% of critically ill patients and canadversely affect both morbidity and mortality [25,26]. Whilstthe mechanisms underlying delayed GE in critical illnessremain poorly defined, ... intestine, CCK andPYY are released in a load-dependent manner from enteroen-docrine cells, predominantly in the proximal small intestine for CCK and the distal small intestine for PYY [5-8]. CCK has...
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Báo cáo y học: "Conceptual issues specifically related to health-related quality of life in critically ill patients" pps
... functional ability may sometimes be the onlyway to determine baseline HRQOL.Response shift in critically ill patientsPatients become accustomed to their illness. An importantmechanism in this adaptive ... measureresponse shift in critically ill patients. Response shift is important not only in longitudinal observations of HRQOL butalso in medical decision making. To measure response shift,some investigators ... highlighted a way to identifypatients with symptoms of PTSD and raised the possibility ofscoring patients at risk before discharging them home,assessing their recovery environment and ensuring thatpatients...
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Báo cáo y học: "Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysis" pdf
... prospectively collected on a daily basis bysenior physicians of the participating ICUs who are clo-sely involved in establishing the database. For all patients,information is recorded at baseline (including ... time-dependent covariates. Yet, this model doesnot deal with the competing risks issue. This issue ariseswhen more than one endpoint is possible [16]. Typically,“dying in hospital” and “discharge alive” ... UO criteriaRisk Increase in serum creatinine ≥1.5 × baseline or decrease in GFR ≥25% <0.5 ml/kg/hour for ≥6 hoursInjury Increase in serum creatinine ≥2 × baseline or decrease in GFR ≥ 50%...
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Báo cáo y học: "Inhalation with Fucose and Galactose for Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients"
... enough to persist in the airways as the mucociliary elevator would remove all pathogens re-siding within mucus layer of the airways´ lining fluid. As this elevator is driven by the beating of the ... Pseudomonas aeruginosa INTRODUCTION Chronic infection of the airways with P. aerugi-nosa is the leading cause of morbidity and mortality in the majority of CF patients (1). This pathogen colonises the ... hypothesized that P. aeruginosa lung infection should be cleared by inhalation of fucose and ga-lactose, which compete for the sugar binding site of the two lectins and thus inhibit the binding...
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Báo cáo y học: "A comparative study of four intensive care outcome prediction models in cardiac surgery patients" pdf
... bed-side; they can only serve as an objective tool in decision making. Although scoring systems may provide an indi-cation of disease severity and prognosis in individualpatients and assist in overall ... than oneminute per patient per day. The parameters included in any scoring system influence its usefulness in differentpopulations of patients. It is, therefore, perhaps not sur-prising that ... acquisition and analysis of data; revisingthe manuscript it critically for important intellectual content. TB: finalapproval of the version to be published. MR: revising the manuscriptcritically...
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Báo cáo y học: "Optimal nutrition during the period of mechanical ventilation decreases mortality in critically ill, long-term acute female patients: a prospective observational cohort study" pptx
... beexplained by not attaining adequate provision of energy andprotein. In the present study we analyze the effects of reaching energyprovision guided by indirect calorimetry and provision of atleast ... mortality for women who reached boththe energy and protein goal, but for men this effect wasabsent.DiscussionReaching nutritional goals, in this study defined as energydelivery with a minimum ... onmortality might thus be explained by inadequate provision ofenergy. No information on protein provision or glycemic con-trol was provided [5]. In the ACCEPT study, the provision ofenergy after...
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Báo cáo y học: " Impact of delayed admission to intensive care units on mortality of critically ill patients: a cohort study" pot
... benefits critically ill patients.Key messages• Demands for ICU beds are increa sing worldwideand delay to ICU admission is becoming a more fre-quent issue.• Thereisanincreaseinmortalityforeachhourofdelay ... 44.8%).Analysis of the delay to ICU admission by multivariateanalysis is presented in Table 3. Each w aiting hour wasassociated indepe ndently with a 1.5% increase in risk ofICU mortality (hazard ... experienced in caring for ICUpatients. Patients in the delayed admission group experi-enced an increase in SOFA score while waiting, reflect-ing worsening of organ dysfunction during this period.General...
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