Báo cáo y học: "Protein C as a surrogate end-point for clinical trials of sepsis" docx

... (up to 7 days), and the efficacy of these infusions for normalization of protein C levels. We agree that these are clinical scenarios in which protein C may have value as a surrogate end-point. ... The Cardiac Arrhythmia Suppression Trial (CAST) Investigators: Preliminary report: effect of encainide and flecainide on mor- tality in a randomized trial of arrhythmia sup...

Ngày tải lên: 13/08/2014, 10:20

... ÔExtra and intracellular nucleotide and nucleoside: chemical signals, metabolic regulators and potential drugsÕ and ÔHyperhomocysteinemia as a cardiovascular risk factor: biochemical mechanism(s)Õ. REFERENCES 1. ... different erythrocyte age/density fractions obtained by isopycnic centrifugation on a Percoll gradient. Methyl esterification in intact erythrocytes was assayed by incubating...

Ngày tải lên: 08/03/2014, 22:20

... present a case of toxoplasmosis that presented as a swelling in the axillary tail of the breast with a palpable axillary lymph node which mimicked breast cancer. Case presentation: A 45-year-old ... cases have been reported [3-5]. We present a case of toxoplasmosis that presented as an axillary tail (breast) mass and a palpable axillary lymph node which mimicked breast c...

Ngày tải lên: 10/08/2014, 23:22

... late-onset Finnish type 1 diabetes subjects. Immunogenetics 2010, 62:101-107. 36. Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, ... Conversely, this defect may not be an absolute requirement and may be absent from many of the cases. A more refined approach, based on genetic-based selection of clinically stratified T1 D...

Ngày tải lên: 18/06/2014, 16:20

... protocol designed for this study, which included epidemiological and demographic data, medical history, clinical features, physical examination, laboratory data (including tests for rheumatoid factor and antinuclear ... potential arthritogenic polymorphism of MICA (major histocompatibility complex class I chain-related gene A) , called MICA -A9 , has been associated with PsA risk ind...

Ngày tải lên: 09/08/2014, 08:23

... Hasegawa, J., Yoshida, T., Yamazaki, T. & Sambongi, Y. , Yu, Y. , Igarashi, Y. , Kodama, T., Yamazaki, K., Kyogoku, Y. & Kobayashi, Y. (1998) Solution structure of thermostable cyto- chrome ... & Ferguson, S.J. (1996) Alteration of haem-attachment and signal-cleavage sites for Paracoccus denitrificans cytochrome c 550 probes pathway of c- type cyto- chrome biogenes...

Ngày tải lên: 24/03/2014, 03:21

... each category. Patients were included if they had a baseline PC measure. Day 4 PC was classified as end of infusion. If day 4 measurement was not availa- ble, last observation carried forward ... greater than 50%. The PTEE for cardiovascular SOFA was 41%. PC predicts cardiovascular changes downstream, and so it is expected that the cardiovas- cular SOFA would be a reasonable surr...

Ngày tải lên: 13/08/2014, 08:21

... replace Arg121 with Lys (R121K) or Gln (R121Q) as described previously [20,30–32]. The muta- genic primers used were 5 0 -CCTGGCCCGGCGAAGGTCA TCTACACC-3 0 for R121K and 5 0 -CCTGGCCCGGCG CAGGTCATCTACACC-3 0 for ... Role of Arg121 on cytotoxicity of a- sarcin (Eur. J. Biochem. 268) 6193 Arginine 121 is a crucial residue for the speci c cytotoxic activity of the ribotoxin a-...

Ngày tải lên: 31/03/2014, 23:20

... Bernasconi NL, Traggiai E, Lanzavecchia A: Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002, 298:2199-2202. 26. Matsumoto I, Maccioni M, Lee DM, Maurice ... drug-resistant human B cell lymphomas to the cytotoxic effect of CDDP, VP1- and toxins [abstract]. FASEB J 1995, 9 :A2 06. 8. Kosmas C, Stamatopoulos K, Stavroyianni N, Tsavaris N, P...

Ngày tải lên: 09/08/2014, 01:21

... ERAD system eliminates unfolded proteins that Commentary Rheumatoid arthritis as a hyper-endoplasmic reticulum- associated degradation disease Satoshi Yamasaki 1 , Naoko Yagishita 1 , Kaneyuki ... Japan 2 Rheumatology, Immunology and Genetics Program, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan Corresponding author: Toshihiro Naka...

Ngày tải lên: 09/08/2014, 07:20