Báo cáo y học: "Involvement of nitric oxide (NO) in cough reflex sensitivity between non-sensitized and OVA-sensitized guinea pigs" pptx

... OVA- induced increase in cough reflex sensitivity only in sen- sitized guinea pigs, but it did not affect the normal cough reflex sensitivity in non-sensitized guinea pigs. Our initial hypothesis ... the iNOS inhibition experiment using NOS inhibitors, in non-sen- sitized guinea pigs with normal cough reflex sensitivity and in OVA-sensitized guinea pi...

Ngày tải lên: 13/08/2014, 10:20

... administered orally and M-4 synthetized from CAM cause a decrease in iNOS expression in cytosol after inflammatory stimu- lation, inhibiting superoxide generation and resulting in prevention of ... treatment of airway inflammatory diseases, since M-4 does not show any antimicrobial activity [17]. NO is primarily derived from a cationic amino acid, L-arginine, and oxygen by a f...

Ngày tải lên: 11/08/2014, 03:20

... treatment of airway inflammatory diseases, since M-4 does not show any antimicrobial activity [17]. NO is primarily derived from a cationic amino acid, L-arginine, and oxygen by a family of NOS. ... the inhibition of TGF-beta signaling in lung fibroblasts. Respir Res 2006, 7:16-29. 13. Tayler BS, Geller DA: Regulation of the inducible nitric oxide synthase (iNOS) gene. In N...

Ngày tải lên: 11/08/2014, 06:22

... col- lections of mucinous material con taining varying combi- nations of mucopolysaccharides and mucoproteins within the adventitial layer of the artery. The cysts exert extrinsic pressure on the ... 4 of 4 Because of the rarity of the disease and the lack of large studies involving long follow-up examinations, the recurrence rate of previously treated CAD of the popli-...

Ngày tải lên: 11/08/2014, 12:20

... prostate tumours analysed by real time P CR and viral protein was detected in 23% of 334 prostate tumours using anti- sera against a panel of murine retroviruses including XMRV [3]. In that study, infection ... Some of these have later been shown to be contaminating animal viruses withunknownoriginandfunction.OnlyHIV- 1and HIV-2, both of which induce acquired immunodefi- ciency...

Ngày tải lên: 12/08/2014, 23:23

... Dhainaut Page 2 of 2 (page number not for citation purposes) safety and efficacy in large international integrated databases of several trials [12], and to identify subgroups of patients in which ... be viewed only as exploratory and a hypothesis-generating activity. For instance, the signifi- cant reduction of mortality with rTFPI observed in the sub- group of sCAP wit...

Ngày tải lên: 13/08/2014, 11:23

... simulans for non-synonymous and synonymous sites of coding data, introns ≤86 bp and introns >86 bp. Error bars indicate two standard errors. Synonymous site divergence is significantly greater than ... only a small fraction of total intronic DNA in the genome. We demonstrate that levels of selective constraint are higher with increasing intron length. Thus, while the majority...

Ngày tải lên: 14/08/2014, 14:21

... 4Overview of the number of one-to-many and many-to-many orthologous relationships in phylogenetic treesOverview of the number of one-to-many and many-to-many orthologous relationships in phylogenetic ... Examples of genes containing this module are CONSTANS, a zinc finger protein linking day length and flowering [41], as well as APRR5 and APRR7, pseudo-response regulator...

Ngày tải lên: 14/08/2014, 17:22

... n = 4. C Immunofluorescence study of CFTR in TSMC and D in the absence of primary antibody. α-smooth muscle actin is stained in red, CFTR in green and nucleus (TOPRO-3 staining) in blue. Scale ... intense debate and remains poorly understood. The role of the airway epithelium in modifying the contractility of the underlying smooth muscle has been suggested but is not...

Ngày tải lên: 12/08/2014, 16:20

... activation of Akt and eNOS [14,15]. Nitric oxide has been shown to be produced from L- arginine by a family of nitric oxide synthase isoforms, including inducible nitric oxide synthase and eNOS, ... hyperpermeability [17,18]. The expression of eNOS may be induced by calcium-dependent binding of calmodulin via proinflammatory cytokines or by serine phos- phorylation thr...

Ngày tải lên: 13/08/2014, 08:20