Báo cáo y học: " The retrovirus RNA trafficking granule: from birth to maturity" pot

... eliminated. The importance of the road traveled to the cytoplasm It is well established that the nuclear history of an mRNA can influence its fate in the cytoplasm. This property can be attributed to the ... modulate RNA fate in the cytoplasm. The journey of retroviral RNA from the nucleus to its ultimate destination in the capsid is likely to be characterize...

Ngày tải lên: 13/08/2014, 09:21

... that any new therapies that alter the intrinsic response to coagulation and inflammatory stimulants would also potentially produce detrimental effects on these, and potentially other, physiological ... originally believed to be exclusively involved in coagulation in the inflammatory response provides an exciting potential mechanism(s) for modification through the application of new...

Ngày tải lên: 12/08/2014, 19:21

... comparison of the form of both curves, we also show the CD4 trajectory, standardized to the HIV RNA level ten years after seroconversion (i.e. the values in the CD4 curve are divided by 9.09 on the relative ... CI 0.101 to 0.231) per year from 4 to 1.5 years before AIDS diagnosis, and 0.223 (95% CI 0.138 to 0.314) per year for the last 1.5 years before AIDS diagnosis...

Ngày tải lên: 13/08/2014, 05:22

... relatively few genes compared to many other virus families, the retroviridae have evolved over the millenia to maximise the functions of their RNA genome. The genome serves as a versatile template from ... contribu- tions from investigators studying other retroviruses. They have shown both similarities with the HIV-1 motifs, and also, importantly, differences. The fact t...

Ngày tải lên: 13/08/2014, 13:20

... dimeric prototypes for the respective families of c-andb-crystallins, andsimplyreferredtoasc-type or b-type crystallins, respectively. Both monomeric c-type crystallin and the subunit of dimeric b-type ... the crucial role played in evolution by the linkers themselves. They hint at the possibility that circular permutation may have been one of the mechanisms employed in the evol...

Ngày tải lên: 24/03/2014, 04:21

... mechanical hyperalgesia in CFA-induced arthritis. These results highlight the potential for TNF to play a vital role in inflammatory hyperalgesia, both by a direct action on neurons via TNFR1 and by facilitating ... inflammatory disease. Traditionally, macrophage infiltration into the DRG has been thought to play a key role in degeneration and repair of the damaged nervous system [3...

Ngày tải lên: 09/08/2014, 06:23

... lethargy and a one-week history of vomiting, polyuria and polydipsia. An emergency left thyroid lobectomy and left lower parathyroidectomy were performed. There was a prompt decrease in his parathyroid ... parat hyr- oid gland within it was visualised. A biopsy was taken from the left upper parathyroid gland. Histology revealed a 4 cm parathyroid carcinoma within the cyst which was full...

Ngày tải lên: 11/08/2014, 14:21

... cause of the arrhythmia in any of these cases. We have made the assumption that the purpose of the ECG is to identify patients at risk of any sus- tained arrhythmia, and therefore arrhythmias ... gender, and the amount ingested. To investigate the strength of the association between a variety of study factors and arrhythmia, the odds ratio (OR) of exposure to the study...

Ngày tải lên: 12/08/2014, 19:22

Ngày tải lên: 13/08/2014, 10:20

... 40% of the household capacity to pay was taken to be catastrophic [3]. Only 12% of the households could afford to pay the cost associated with the treatment of TBI from household savings. The remaining ... The YLD caused by TBI in one year was then calculated using the basic formula applied by The Global Burden of Disease and Injury: YLD = I × DW × L where I is the n...

Ngày tải lên: 13/08/2014, 11:22