Báo cáo y học: " Patterns of evolution of host proteins involved in retroviral pathogenesis" potx

... Identifying signatures of genetic conflict can open the way to biological testing of hypotheses regarding the function of host proteins. In ret- rovirology, the utility of this approach was recently ... indicative of a genetic conflict. Finally, the absence of a signature of positive Darwinian selection in Cyclophilin A provides a complement to the understanding of the...

Ngày tải lên: 13/08/2014, 09:21

... establishment of tissue identity but seem to be important for the maintenance of cells in differentiated states. It is likely, then, that miRNAs facilitate evolution of complexity by stabilizing existing ... miRNAs in Platynereis using whole mount in situ hybridization and found that expression patterns of these miRNAs are highly specific for certain tissues and cell typ...

Ngày tải lên: 09/08/2014, 20:21

... necessary for motor activity and trophism. This is the point of empirical entry into testing a hypothetical inference from the math on a human W in a clinical setting. A battery discharging into ... rate of the organic battery is influenced not just by the size of the mass, as Kleiber would have it, but also by the availability of energy to it, and by the ability of the organic ba...

Ngày tải lên: 13/08/2014, 16:20

... sub-regions that encode proteins showing homology to other types of lyases, likely involved in binding phycobilins to one or both PEs. These lyases include CpeY and CpeZ, which in F. diplosiphon were ... Plöscher M, Eichacker L, Yang B, Zhou M, Scheer H: Phycobilin:cystein-84 biliprotein lyase, a near-universal lyase for cysteine-84-binding sites in cyano- bacterial phycobiliprote...

Ngày tải lên: 14/08/2014, 08:20

... in this light, the special decoding arrangements for selenocysteine, including its in situ modification from seryl-tRNA into selenocysteinyl- tRNA, can be interpreted as exactly the sort of evolutionary intermediate ... approximately 900 amino acids which are produced by natural biosynthetic pathways [54,55]; and engineered, at least 118 amino acids which have been experimentally engine...

Ngày tải lên: 14/08/2014, 16:20

... regulatory element (SRE). This is a binding site specif- ically recognized by the cholesterol sensing proteins SREBPs (sterol regulatory element binding proteins) , which are known to play a key role in ... Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding pro- t...

Ngày tải lên: 14/08/2014, 17:22

... fraction of intronic regions have func- tions and that they are likely to be evolving under the influ- ence of natural selection, mostly purifying selection. The effects of selective constraints on patterns ... ordinal position of introns (relative to other introns of the same gene)Figure 1 Mean K i as a function of the ordinal position of introns (relative to other introns...

Ngày tải lên: 14/08/2014, 17:22

... polyclonal antibodyDetection of β 3 integrin in sections of human peri-implant by immunohistochemistry using a rabbit polyclonal antibody. (a, b) β 3 Integrin is evident in the membrane of ... 2 Sections of human peri-implant tissues stained by hematoxylin and eosinSections of human peri-implant tissues stained by hematoxylin and eosin. (a) Multinucleated cell associated with...

Ngày tải lên: 09/08/2014, 07:20

... factors are indeed important for optimizing DNA-microarray data quality. In order to assess the reproducibility of- and factors involved in DNA-microarray data produced in our laboratory during transcriptome ... enzyme for the Cy3 label and (ii) prolonged exposure to air and light of the dyes increasing the chance of oxidation and / or bleaching. The main contributing factors...

Ngày tải lên: 14/08/2014, 14:21

... role of BiP in binding to and retaining unassembled subunit proteins [9,49] and in folding and assembly of immunoglobulin chains in cells that are highly active in terms of recombinant protein ... when increasing amounts of light chain are available for IgG assembly. The association of BiP with folding and assembly of recombinant immunoglobulin chains in plants is sign...

Ngày tải lên: 31/03/2014, 08:20