Báo cáo y học: " It''''''''s the virus, stupid – part 2" ppsx
Báo cáo y học: " It''''s the virus, stupid – part 2" ppsx
... purposes) Retrovirology Open Access Editorial It's the virus, stupid – part 2 Ben Berkhout* Address: Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Email: ... block the furiously rep- licating virus with antivirals, instead of resolving the disease by modulating the immune system. Nevertheless, the fre...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "It’s all in the blood: circulating endothelial progenitor cells link synovial vascularity with cardiovascular mortality in rheumatoid arthritis" docx
... nutrients and oxygen to the synovial tissue in RA, which by virtue of its proliferative nature becomes rapidly hypoxic [1]. The presence of EPC in RA synovium could result from their enhanced ... for the classical risk factors such as raised levels of low-density lipoprotein cholesterol, there is also strong evidence for endothelial dysfunction in RA. This was certainly seen in the st...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody" ppsx
... vitro. Why should FIV alter the way it interacts with CD134? Our studies with antago- nists of the CD134 interaction suggest that the affinity of the Env for the primary receptor CD134 may alter ... neutralising antibody and the way in which a single epitope may dominate within polyclonal sera [63- 66]. Understanding the process of immune evasion may yield valuable insights into...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... to activity of the indirect pathway of glycogen synthesis. In addition, this study reports for the first time the simultaneous detection of increased signal intensity for the glycogen C2–C5 resonances. These ... in the 13 C NMR methodology, the observation of simultaneously enhanced indirect hepatic glycogen synthesis and glycolysis in the ADM group has clarified the in vivo act...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo y học: "Clinical review: The management of hypertensive crises" ppsx
... pre-existing hypertension. The risks for developing malignant hypertension are related to the severity of the underlying hypertension, and therefore the role of mechanical stress on the vessel wall ... from the kidney. The release of vaso- constrictor substances from the kidney has long been postulated to play a central role in the pathophysiology of malignant hypertension [...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: ": Isotonic saline – the only solution to recommend" ppsx
... 14:325. 2. Kozek-Langenecker SA: In uence of uid therapy on the haemostatic system of intensive care patients. Best Pract Res Clin Anaesthesiol 2009, 23:225-236. 3. Soonawala D, Middelburg ... Egger M, Vandenbroucke JP, Dekkers OM: E cacy of experimental treatments compared with standard treatments in non-inferiority trials: a meta-analysis of randomized controlled trials. Int J .....
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: " Deletion of the meq gene significantly decreases immunosuppression in chickens caused by pathogenic marek’s disease virus" pptx
... is involved in early cytolytic infection of lymphocytes, but not the induction of tumors [11]. Recently studies showed that the mechanism of attenuation of MDV does not involve the 132 bp repeat ... obtained by centrifugation. Lymphocytes from the buffy-coats were counted, dil uted to 10 6 cells/ml and duplicated 35-mm plates of freshly seeded CEF monolayers infected with 10 6 lymphoc...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: " Classic swine fever virus NS2 protein leads to the induction of cell cycle arrest at S-phase and endoplasmic reticulum stress" potx
... activation. Additionally, NS2 induces cell cycle Figure 3 The analysis of the stages of cell division of expressing CSFV NS2 protein by flow cytometry. (A) Histograms f rom flow cytometry data for propidium ... to amplify the human cyclin A nucleotide sequences (GenBank: X51688) and used to amplify the porcine cyclin A gene by RT-PCR given that significant homology is likely to exist...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: " Kaposi''''s sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat" pptx
... have recently generated point mutants of the vFLIP K13 which differ in their ability to activate the NF-κB pathway [27]. In order to test the hypothesis that vFLIP K13 activates the HIV-1 LTR ... infect distinct cell types. Thus, HHV8 is typically believed to infect B lymphocytes, epithelial cells, keratinocytes, KS tumor cells, and endothelial cells [40,41], while the predominant h...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"
... inhibited by recombinant HBs but not by the recombinant LHBs. The binding of SHBs with human hepatocytes was further supported by the observation from Bruin et al [39]. They have found that the particles ... Recent data suggests that DHBV may use the endocytosis way for its entry [66]. This hypothesis was supported by the observation of the conformation change of the larg...
Ngày tải lên: 03/11/2012, 10:09