... repeated 1,000 times to estimate the distribution of the test statistic. The distribution was estimated in 10different runs to check that it was stable. Using the result-ing distribution, the ... HTLV -I- specific CD8+cytotoxic T lymphocyte (CTL) frequency [2,3], suggestingthat virus- host immunology interactions are important in determining the outcome of infection. It is not knownwhether the ... it hard to interpret since it was not knownhow much of the between-individual variation in TaxmRNA was attributable to variation in the HTLV -I- specificCTL response. In particular, systematic...