Báo cáo y học: " Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency" docx
Báo cáo y học: " Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency" docx
... of 14 (page number not for citation purposes) Retrovirology Open Access Research Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency Sandie ... microarray analysis was to iden- tify candidate genes potentially involved in the control of the HIV latency. For this reason, we decided to focu...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: " Isolated radial head dislocation, a rare and easily missed injury in the presence of major distracting injuries: a case report" ppsx
... was involved in reviewing the literature and proof reading of the manuscript. RSUY has approved the final manuscript. SSB is the senior author and was responsible for final proof reading of the ... later, the patient complained of pain in the right elbow. There was no previous history of elbow injury or arthritis. On examination, there was minimal swelling over...
Ngày tải lên: 11/08/2014, 10:22
Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt
... IFN-β is influencing monocyte recruitment, survival, and/ or retention in the synovial joint. Alternatively, IFN-β may inhibit inflammatory cell infiltration indirectly, via suppression of FLS and/ or ... infiltration and erosion of bone were observed in the ankle joint. In CIA mice treated with the highest dose of IFN-β (2.5 µg per injection per mouse), limited hyperpla...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
... damage by injection of interleukin-1 (IL-1) into murine knee joints. After 2 days, we injected an adenovirus encoding TGFβ. On day 4, we measured proteoglycan (PG) synthesis and content. To examine ... overexpression of TGFβ stimulated repair of IL-1- and OA-damaged cartilage. TGFβ- induced synovial fibrosis was blocked by locally inhibiting TGFβ signaling in the synovial lining...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Part I, Patient perspective: activating patients to engage their providers in the use of evidencebased medicine: a qualitative evaluation of the VA Project to Implement Diuretics (VAPID)" ppsx
... following instruction appears to be ingrained in their reasoning for bringing in the letter. These indivi- dualsstatedtheyweresimplydoingwhattheletter requested of them. ‘For one thing I was told and ... participating in the study and for bring ing in the letter for discussion. For sev eral patients it was their way of ‘paying back’ the military and other veterans, w...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... similar binding proper- ties and in vitro activities to the BLyS and APRIL homo- trimers, and may be present in sera in similar amounts to APRIL and BLyS, we postulate that they may likely play similar ... of assay buffer. Wells were then resuspended in 100 μl of assay buffer and analyzed by using a Luminex 100 mac hine (Luminex Corporation, Austin, TX, USA). The tot...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: "Pro/con clinical debate: Is high-frequency oscillatory ventilation useful in the management of adult patients with respiratory failure" ppt
... What is the safety and efficacy of the device? As outlined in the following debate, there are several compelling arguments for and against the use of HFOV at this point in adults. Keywords acute ... oscillatory ventilation (HFOV) has become an increasingly common therapy. This may not have been the case if researchers had not persisted in investigating the therapy af...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice" pdf
... colleagues, cytokines were measured in the BALF, while in our study and in the study of Vaneker and colleagues cytokines were measured in lung homogenate. Maybe cytokines were still in the sub-epithelium and ... behind VILI and the contribution of MV to lung injury in the absence of pre-existing lung injury. Competing interests The authors declare that th...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... sequencing on the two proteins, the purified protein bands were blotted onto a polyvinylidene difluoride membrane, and the individual proteins were subjected to N-terminal sequencing. The N-terminus of ... IR. Results of each values were expressed as the following ratio: intensity of WD cDNA/intensity of competitor and then divided by intensity of amplified actin cDNA....
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps
... result in the increased synthesis and activation of MMPs, increased release of proteoglycan, and increased cell death. These effects are abrogated by treatment with the PKR inhibitor 2-aminopurine. ... mM) inhibitor of PKR to investigate the role of PKR in the TNF-α- and ceramide-signalling pathways in cartilage degradation. The use of 2-AP as an inhibitor of...
Ngày tải lên: 09/08/2014, 01:23