... Retrovirology 2008, 5:8.4. Ye Y, De Leon J, Yokoyama N, Naidu Y, Camerini D: DBR1 siRNA inhibition of HIV- 1 replication. Retrovirology 2005, 2:63.5. Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman ... up-regulation of GliPR by HIV- 1 and the early significant inhibition of HIV- 1 replication mediated by knockdown of GliPR reveal GliPR as an important HIV- 1 dependency factor (HDF), which may be exploited ... theeffect of GliPR suppression by siRNA on HIV- 1 replication.Results: Induction of GliPR expression by HIV- 1 was confi rmed in P4-CCR5 cells. When GliPR was suppressed by siRNA, HIV- 1 replication...