Báo cáo y học: " Presence of a functional but dispensable Nuclear Export Signal in the HTLV-2 Tax protein" pdf
Báo cáo y học: " Presence of a functional but dispensable Nuclear Export Signal in the HTLV-2 Tax protein" pdf
... domain is dispensable for the Tax2 localization.Results HTLV-2 Tax protein sequence contains a putative NES domainWe lately demonstrated that the HTLV-2 Tax protein hasan intracellular localization ... AccessResearch Presence of a functional but dispensable Nuclear Export Signal in the HTLV-2 Tax proteinSébastien A Chevalier1, Laurent Meertens1, Sara Calattini1, Antoine Gessain1, Lars ... the HTLV-2 Tax protein has anyrole during the viral cycle.Within the context of a full length Tax2 protein, the presence of a functional NES2 domain is dispensable for the protein local-izationFigure...
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Báo cáo y học: " Implementation of a new emergency medical communication centre organization in Finland an evaluation, with performance indicators"
... emergencymedical call centre organization reform in Finland.Material and methods A retrospective observational study was conducted in the EMCC in East and Central Uusimaa, an area of southern Finland ... reform in Finlandhad negative effects on the appropriate use of ambu-lances, and the reform caused prolongation in the answering and processing times of emergency calls in Helsinki, the capital of ... severaldatabases. Approximately 40% of all emergency calls dur-ing the period 2002-2005 were available from the munici-pality-based databases. The rest of the data could not begathered since it was...
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Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)
... inventory of normalized mathematical indexes of abnormality. It is the pattern of these mathematical indexes of abnormality, ob-tained from analysis of multiple cardiac cycles of the resting ... analyzed using the same software and hardware located at the central server location in New York. All MCG analyses in this da-tabase have been validated against the final medical and angiographic ... before the data analysis was carried out. The quality of the tracing was visually rechecked and graded as “good,” “mar-ginal,” or “poor”. A poor tracing was defined by one of the following:...
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Báo cáo y học: "Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion" pot
... used as controls (chronicuntreated). Among the HAART treated animals, one(#20929) had undetectable PVL at the initiation of ther-apy (day 0), but was nevertheless included in the analy-sis since ... intermediate between what wasobserved in macaques treated as early as 4 h pi andmacaques treated during early chronic infection. Thus, the PVL at day 21 pi was significantly lower in HAARTtreated animals ... three of these animalswere killed at day 14 (chronic HAART 14d) and the other three at day 28 (chronic HAART 28d) after the onset of treatment. Three untreated animals at the samestage of infection...
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Báo cáo y học: " Construction of a polycystic ovarian syndrome (PCOS) pathway based on the interactions of PCOS-related proteins retrieved from bibliomic data" docx
... of the hypothetical proteins did not haveany recognizable domains or protein family signatures in their sequences. Only one hypothetical protein(KIAA0247) had domain, family and superfamily ... and dyslipidaemia. The mainpurpose of this study was to identify possible candidate genes involved in PCOS. Several genomicapproaches, including linkage analysis and microarray analysis, have ... Biology (INBIOSIS), Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor, MalaysiaEmail: Zeti-Azura Mohamed-Hussein* - zeti@ukm.my; Sarahani Harun - hani.sarah@gmail.com* Corresponding author...
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Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx
... antithrombin, a single-chain 51 kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is signifi-cantly enhanced by heparin, a type of glycosaminoglycan(GAG) ... 3Heparin stimulates antithrombin (AT) activity in the presence of hyaluronic acid (HA)Heparin stimulates antithrombin (AT) activity in the presence of hyaluronic acid (HA). Heparin (10 µg/ml) and ... destruction of RAjoint tissue, a remarkable quantity of various GAGCS = chondroitin sulfate; GAG = glycosaminoglycan; HA = hyaluronic acid; KS = keratan sulfate; PADI = peptidylarginine deiminase; RA...
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Báo cáo y học: " Responses of FEV6, FVC, and FET to inhaled bronchodilator in the adult general population" ppt
... study indicates that increase of FVC in response to inhaled salbutamol in the bronchodilationtest in a general population sample is infrequent and isonly rarely associated to increased expiratory ... may partially reflect flow changesalso in small airways. Variables regarded to representsmall airways (MEF50, MMEF) have greater inter- andintra-session variability than FEV6 [35,36] and ... significant changes in bronchodilationtesting, it is necessary to evaluate also the inherent meas-urement variability. In a large patient sample, the intra-session repeatability of FVC has been...
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Báo cáo y học: "Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor b pathway in patients with systemic sclerosis" pot
... contributed to the interpretation of data and drafted the manuscript. All authors read and approved the final manuscript.Competing interests The authors declare that they have no competing interests.Received: ... (y- axis). B and D are magnifications of the delineated zones in A and C, respectively. Proteins of interest areindicated by the protein ID provided by ImageMaster 2D Platinum 6.0software or their ... visualize the transferred proteins. 2-D immunoblots were scanned before andafter colloidal gold staining with the use of a densitometer, then analysed by using image analysis software, and finally...
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Báo cáo y học: "Effects of redox cycling compounds on DT diaphorase activity in the liver of rainbow trout (Oncorhynchus mykiss)" doc
... was determined using the BCA ProteinAssay Kit (Pierce, USA), with BSA as standard.Statistical analysisData were analyzed with one-way analysis of variance(ANOVA) and, following significant ... activity in rainbow trout [27]. In the present study,both β-NF and B (a) P caused an increase in hepatic DTDactivity in rainbow trout. β-NF and B (a) P also caused a strong increase in the CYP 1A mediated ... Integrated use of biomarkers (acetylcholineste-rase and antioxidant enzymes activities) in Mytilus gallopro-vincialis and Mullus barbatusin an Italian coastal marine area.Mar Pollut Bull 2003,...
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Báo cáo y học: " Intracellular HIV-1 Gag localization is impaired by mutations in the nucleocapsid zinc fingers" pdf
... both the gRNA and the NCdomain of HIV-1 Gag, and to have a role in HIV-1 gRNAencapsidation and Gag assembly [48,49]. Mapping the interaction domain between Staufen and Gag reveals the Intracellular ... GCGCGATC-GATTGTAATAAACCCGAAAATTTTG. The PCR DNAproduct of 132 bp was separated on a 2% agarose gel andvisualized by ethidium bromide staining. The gel imageswere quantified by Metamorph software ... deletion of the NC domain results in gRNAinstability, possibly due to impaired interactions betweenGag and the gRNA. In addition, colocalization of the mutated Gag and the gRNA disappeared at the...
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