Báo cáo y học: " Processing sites in the human immunodeficie

Báo cáo y học: " Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates" ppt

... human immunodeficiency virus type 1 (HIV -1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates Steve C Pettit 1, 3,6 , Jeffrey N Lindquist 2,5 , Andrew H Kaplan 1 and ... of Gag-Pro-Pol by mature protease in trans. The initial cleav- age occurs at the p2/NC site (presumably at the same rate this site is cleaved in...

Ngày tải lên : 13/08/2014, 09:21

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Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx

... was the creation of the L 17 10 11 mutation that was found to specify a strong ts att phenotype. The L 17 10 11 mutation was originally identified as an attenuating point mutation, L T1 711 I , ... 17 11) were deleted to yield the L 17 10 11 mutation. This gave us two genetically stabilized ts att mutations in L, the L 17 10 11 and the L Y9 42A mutations. In the...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo hóa học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" docx

... HN T553A and C 17 0 mutations to rHPIV1- C R84G L 17 10 11 to generate the rHPIV1-C R84G/ 17 0 HN T553A L 17 10 11 further attenuated the virus in AGMs, restricting virus replication in comparison ... posi- tions 17 10 11 of the L gene of HPIV1 (Table 1) . The mutations in Table 1 were introduced into the HPIV1 antigenomic cDNA individually or in combinations...

Ngày tải lên : 20/06/2014, 01:20

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Báo cáo y học: "Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5a-mediated restriction" docx

... T, Matsui M, Io K, Sato T, Sato H, Uchiyama T: Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV -1 Vif. Nat Struct Mol Biol 2008, 15 :11 84 -11 91. 53. Labute P: The ... substituti on at the 11 8 th amino acid of SIVmac239 CA, corresponding to the 12 0 th amino acid of HIV-2 GH123, also increased susceptibility to Rh TRIM5 a , indicating that g...

Ngày tải lên : 13/08/2014, 01:20

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Báo cáo y học: "Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects" pptx

... N 2 /13 N 14 /15 N 5 /14 K 15 /15 K 7 /12 E 3 /13 K 12 /12 K 6/8 K 5 /14 G 13 /13 E 14 /19 K 14 /14 K 19 /19 K 11 /11 E 2/7 K 11 /13 K 1/ 15 K 5 /14 E 4 /12 K 10 /13 R 1/ 8 Q 8 /14 R 5 /19 Q 2 /10 R 4 /14 T 1/ 12 E 1/ 8 R 1/ 14 346 Val 37.6% Ala ... 26.8% Ser 11. 2% Phe 0.2% Tyr 0% VA 5 /16 V 15 /15 V 10 /10 V 4 /13 V 15 /15 V 10 /14 VV 3 /12 V 6...

Ngày tải lên : 13/08/2014, 05:21

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Báo cáo y học: "Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum" doc

... K, Yewdell JW: CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin- conjugating pathway. J Virol 19 98, ... membrane-spanning domain of the human immunodeficiency virus type 1 Vpu protein. Virology 19 98, 2 51: 96 -10 7. 54. Gottlinger HG, Dorfman T, Cohen EA, Haseltine W...

Ngày tải lên : 13/08/2014, 05:22

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Báo cáo y học: "Dialysis dose in acute kidney injury: no time for therapeutic nihilism – a critical appraisal of the Acute Renal Failure Trial Network study" ppt

... the delivery of dialysis in acute renal failure. Kidney Int 19 99, 55 :15 01- 1508. 19 . Clark WR, Ronco C: Factors influencing therapy delivery in acute dialysis. Contrib Nephrol 20 01, 13 2:304- 312 . 20. ... kidney injury. Proposed by Ronco. Reprinted with permission from [24]. estimated in the years following the National Cooperative Dialysis Study [25]: these years led t...

Ngày tải lên : 13/08/2014, 11:22

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Báo cáo hóa học: " The inhibition of the Human Immunodeficiency Virus type 1 activity by crude and purified human pregnancy plug mucus and mucins in an inhibition assay" ppt

... physically aggregating the virus than by blocking putative viral binding sites or receptors on the cells. The virus and mucins were incubated together with the cells for different incubation periods, ... purposes) entry into the cells and therefore prevent the production of p24 antigen. To further confirm the hypothesis that mucins inhibit HIV -1 activity by phy...

Ngày tải lên : 20/06/2014, 01:20

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Báo cáo y học: " Forefoot pathology in rheumatoid arthritis identified with ultrasound may not localise to areas of highest pressure: cohort observations at baseline and twelve months" ppt

... 13 (11 %) 13 (11 %) Pathology Lateral dominance Medial dominance Equally distributed No pathology Baseline Left SynHy Right 37 (33%) 31 (27%) 19 (17 %) 25 (22%) 15 (13 %) 10 ... (77%) 1 (1% ) 2 (2%) 6 (5%) 6 (5%) 11 (10 %) 18 (16 %) Left BurHy Right 58 ( 51% ) 56 (49%) 18 (16 %) 13 (11 %) 20 (18 %) 27 (24%) 18 (16 %) 18 (16 %) Twelve Month...

Ngày tải lên : 10/08/2014, 21:24

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Báo cáo y học: "Inflammatory responses in epithelia: endotoxininduced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells" pot

... each time point was assayed for different inflammatory cytokines (A) by the RayBio Mouse Cytokine Antibody Array I. (B) Layout of the mouse cytokine protein array on the membrane. Abbreviations POS ... markers are regulated by NFB, the studies recorded here show that they likely are not regulated by the same NFB subunits, or NFB activating machinery. Therefore, unders...

Ngày tải lên : 11/08/2014, 03:20

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