Báo cáo y học: " Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms" pps

... Tamiya S, Koga S, Mita S, Uch- ino M, Mitsuya H, Matsuoka M: Impaired production of naive T lymphocytes in human T-cell leukemia virus type I- infected individuals: its implications in the immunodeficient ... 1 of 16 (page number not for citation purposes) Retrovirology Open Access Research Silencing of human T-cell leukemia virus type I gene transcription...

Ngày tải lên: 13/08/2014, 09:21

... 2461612100, E-mail: dieter.willbold@uni-duesseldorf.de Abbreviations: HIV, human immunodeficiency virus; HIV-1, HIV type 1; rmsd, root mean square deviation; SIV, simian immunodeficiency virus; Vpr, virus protein ... dodecylphos- phocholine micelles; NMR. Human immunodeficiency virus type 1 (HIV-1) is a member of the lentivirus family. In addition to the gag, pol and env genes p...

Ngày tải lên: 24/03/2014, 04:21

... polarisation of type I collagen (CI)-responsive T-cell lines. Cytokine expression of T-cell lines was determined by intracellular (IC) staining of PMA (phorbol 12-myristate 13-acetate)/ionomycin ... reactivity to CI, which was significantly higher than the proportion of controls (healthy and rheumatoid arthritis combined) responsive to CI (p = 0.009). Figure 2 Phenotypic...

Ngày tải lên: 09/08/2014, 08:22

... characterized by insulin re- sistance and insulin secretion deficiency. At present, there is no a single medication which treats type 2 diabetes by improving both insulin resistance and insulin ... inactivation by dipeptidyl peptidase IV and by renal clearance [5, 6, 13]. Many attempts have been made to increase its biological half-life and its efficacy in vivo by producing...

Ngày tải lên: 25/10/2012, 11:10

... 228 Osmotic fragility behavior of pravastatin loaded eryth- rocytes Osmotic fragility determines the susceptibility of erythrocytes to osmotic lysis in respect to serial dilu- tion of NaCl. ... http://www.medsci.org 223 The pharmacologically active form of pravas- tatin is open hydroxyl-acid so that its hydrophilicity is markedly higher than that of other statins. The oral...

Ngày tải lên: 25/10/2012, 11:10

... leakage induced by intrinsic membrane interaction using purified TRAIL and liposome systems. Release rate of liposome-entrapped dye induced by TRAIL as well as membrane binding ability of TRAIL were ... necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) is a member of the TNF family and its soluble form exhibited apoptotic activity for various cancer cell lines with mini...

Ngày tải lên: 31/03/2014, 08:20

... cell-mediated immunity, or delayed -type hypersensi- tivity, which was characterized by the ability of these cells to induce inflammatory reactions mainly characterized by the activation of macrophages. ... plays a critical role in inducing/maintaining acces- sibility at the second intron HSII and HSIII DNase I hypersensitive sites of the Il4 locus [32]. Indeed, STAT-5 is bound t...

Ngày tải lên: 09/08/2014, 14:22

... exhibited an inhibition of cell viability and promoter activity in HIV-1 infected cells Following the identification of alsterpaullone as the drug with the highest selectivity in inhibiting HIV-1 ... Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild -type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 b...

Ngày tải lên: 10/08/2014, 05:21

... infec- tivity, protease inhibitors targeting the catalytic site have been routinely used in combination with inhibit ors tar- geting other viral components in antiretroviral therapy (ART). In contrast ... autoprocessing in the context of the provirus, which is missing in the GST fusion precursor system. In the context of the provirus, a combination of reduced catalytic activity and a vi...

Ngày tải lên: 10/08/2014, 05:21

... HPV genotypes, including all high -risk HPV genotypes, were combined with nested PCR amplifications of type- spe- cific primers. Despite robust detection of the IFN-g Figure 4 Vulvar intra-epithelial ... stroma is heavily infiltrated. Figure 5 The CLINICAL ARRAYS Human Papillomavirus Kit was used for HPV typing. The combination of the three dark diagonal points indicates the presence...

Ngày tải lên: 10/08/2014, 23:21