Báo cáo y học: " Dual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production" doc

... influence of the SR proteins on Gag and Env synthesis was further evaluated with respect to virion production and infectivity. Influence of SR proteins on virion production and infectivity This ... (see discussion). Influence of the SR proteins on Gag and Env expression analysed by immuno-confocal microscopy To better understand the influence of...

Ngày tải lên: 13/08/2014, 09:21

... histopatho- logical changes only on day 14 and day 18 when STA-5326 was administered during the entire course of EAU, the possi- bility exists that STA-5326 may be merely delaying the onset of EAU rather than ... after uveitogenic effector cells have been primed [25]. Down-regu- lation of the IL-12/Th1 pathway and the IL-23/Th17 pathway may be necessary for significant a...

Ngày tải lên: 09/08/2014, 13:22

... intra-aortically and proximally to the occluded segment, 15 min prior to the release of aorta occlusion by deflation of the balloon. When 30 min of aorta occlusion was completed, the balloon was deflated and ... spinal cord ischemia and contributes to axonal demyelination and dysfunction with long-term neurological deficits. On the other hand, peroxynitrite anion (ON...

Ngày tải lên: 10/08/2014, 10:20

... significantly decreased synthesis of total and HDM-specific IgE compared with controls. Analysis of the cytokine profile of lymphocytes after challenge with HDM crude extract revealed that mRNA expression ... center of the lung. In grade 3, the perivascular and peribronchial infiltrates extended to the periphery of the lung. Measuring cytokine mRNA expression Measuring...

Ngày tải lên: 13/08/2014, 13:22

... completely inhibited SIV replication in 2 of the 3 monkeys, but cells from the third macaque, with the highest viral titer, only responded at the high WR1065 dose. Conclusion: The study demonstrates ... Inhibition of HIV-1 replication in human TCBs by WR1065 and amifostine. Concentration (μM) Number of experiments % Inhibition of a HIV-1 replication (mean ± SE) % Viab...

Ngày tải lên: 10/08/2014, 05:21

... data on the effect of chlorhexidine on HIV-1 RNA accumulation/cell viability and AM provided data on the effect of overexpression of CLK2 KR on viral gene expression. Both WD and SGO provided HIV-1 ... illustration of the spliced RNAs generated by processing of the HIV-1 genomic RNA. Indicated are the common (open boxes) and alternative (closed...

Ngày tải lên: 13/08/2014, 01:20

... 2 mRNA expression of inflammatory mediators and cytokines related to bone destructionmRNA expression of inflammatory mediators and cytokines related to bone destruction. (a) Expression of mRNA ... arthritic mice, and may account for the bone protective properties of VIP in RA. On the other hand, its effects on the expression of OPG further support the postulated bo...

Ngày tải lên: 09/08/2014, 06:23

... publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Authors’ contributions GB conceived of the ... report and conducted work. GU conceived of the report and conducted work. CM conceived of the report and conducted work. AR conceived of the report and condu...

Ngày tải lên: 11/08/2014, 17:21

... questions have not yet been addressed. The first question is whether the expression level for RIZ1 varies over the progression of cancer; and the second question is whether the PR domain alone ... activity. In this study, we quan- titatively analyzed the mRNA expression level of RIZ1 over the disease progression in eight different types of cancer, and evaluated th...

Ngày tải lên: 25/10/2012, 11:15

... as the real-time imaging unit of the system, guiding the target tissue volume, monitoring the energy deposition and the therapeutic effect, and also controlling the US exposure based on the ... infiltration, consisting primarily of lymphocytes and monocytes sometimes with small number of eosinocytes, were seen between the necrotic and normal zones. In add...

Ngày tải lên: 25/10/2012, 11:18