Báo cáo y học: " APOBEC3G targets human T-cell leukemia virus type 1" docx
Báo cáo Y học: Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution pptx
... incorporation of Vpr. Keywords: HIV-1; Vpr; solution structure; dodecylphos- phocholine micelles; NMR. Human immunodeficiency virus type 1 (HIV-1) is a member of the lentivirus family. In addition to ... Ju ¨ lich, IBI-2, Germany Human immunodeficiency virus type 1 protein R (HIV-1 Vpr) promotes nuclear entry of viral nucleic acids in nondividing cells, causes G 2 cell cycle arrest...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: " APOBEC3G targets human T-cell leukemia virus type 1" docx
... activity of APOBEC3G on human T-cell leukemia virus type 1 (HTLV-1), the first identified human retrovirus. Results: In this study, we have demonstrated that overexpressed as well as endogenous APOBEC3G ... enzyme-catalytic polypeptide-like 3G (APOBEC3G) is a host cellular protein with a broad antiviral activity. It inhibits infectivitiy of a wide variety of retroviruses by d...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Acute lymphocytic crisis following herpes simplex type 1 virus hepatitis in a nonimmunocompromised man: a case report" pptx
... virus (EBV), cytomegalovirus (CMV), herpes virus zoster, toxoplasma, coxsackie, mycoplasma pneu- moniae, hepatitis B virus, hepatitis A virus, adenovirus, echo virus, human immunodeficiency virus ... and the human immunodeficiency virus (HIV-1). Other infections have been implicated as occasional etiologies of the mononucleosis syndrome, including human herpes virus type...
Ngày tải lên: 11/08/2014, 14:20
Báo cáo y học: "Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis" ppt
... Increased peptidylarginine deiminase type II in hypoxic astrocytes. Biochem Biophys Res Commun 2004, 325:1324-1329. 70. Ishigami A, Ohsawa T, Hiratsuka M, Taguchi H, Kobayashi S, Saito Y, Murayama S, ... therapeutic use of tetracyclines in RA [23], Knuckley and colleagues [28] screened tetra- cycline derivatives (minocycline, doxycycline, tetracy- cline, and chlortetracycline) for their...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"
... applying them therapeutically [5, 6]. Type 2 diabetes is characterized by insulin re- sistance and insulin secretion deficiency. At present, there is no a single medication which treats type ... for type 2 diabetes [3, 12]. However, the clinical application of native GLP-1 is hampered by its very short plasma half-life [5, 6, 13]. This is due to its rapid inactivation by dipeptidyl...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... fragility of loaded erythrocyte at 2, 4, 8 mg/ml pravastatin when com- pared to that of unloaded erythrocytes (Table 4). Table 4, Erythrocyte osmotic fragility of unloaded eryth- rocytes and erythrocytes ... loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocytes sus- pended in PBS, and pravastatin-loaded e...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf
... Choi, Y. H., Sung, B.J., Shin, N.G., Shin, H C., Sung, Y. C. & Oh, B H. (1999a) 2.8 A ˚ resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 11, ... family. Recently, the crystal structure of human TRAIL showed that TRAIL is a homotrimeric protein whose subunits contain mainly b-sheets. We characterized the structural changes of recombi...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... N,N¢-diisopropylethylamine; DMS, dimethylsulfide; EDT, ethanedithiol; hCt, human calcitonin; MBHA, 4-methyl benzhydryl- amine resin; Mtt, 4-methyltrityl; Pip, 2-phenylisopropyl; OFm, fluoren-9-yl methylester; sCt, salmon ... in vivo hypocalcemic potencies were assessed. The novel analogues include cyclo17,21-[Asp17, D -Phe19, Lys21]hCt (2), cyclo17,21-[Asp17,Aib18,Lys21]hCt (3), cyclo17,21-[A...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "The proliferative human monocyte subpopulation contains osteoclast precursors" ppt
... cytokine-free, serum-free system. J Immunol Methods 1992, 153:201-212. 23. Cheung DL, Hamilton JA: Regulation of human monocyte DNA synthesis by colony-stimulating factors, cytokines, and cyclic adenosine ... GM-CSF on human monocyte DNA synthesis and CSF receptor expression. J Interferon Cytokine Res 1999, 19:417-423. 22. Bennett S, Por SB, Stanley ER, Breit SN: Monocyte proliferation in...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes" ppt
... restoration of proteoglycan synthesis by human OA chondrocytes. IGFBPs secreted by human OA cartilage or cultured chondrocytes were analyzed by western ligand blot. The ability of NBI-31772 to displace ... ineffective in promoting proteoglycan synthesis by chondrocytes. By contrast, 2.7 nM R 3 IGF-1 significantly stimulated total proteoglycan synthesis, by 45% over that by unstimulated c...
Ngày tải lên: 09/08/2014, 01:23