Báo cáo y học: "Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)" pps

... immune dysregulation and autoimmunity such as chronic lymphocytic leukemia and multiple sclerosis. It raises the question of whether atypical presentations of herpes simplex virus encephalitis warrant ... in patients with MS have failed to find a statistically significant association [10]. There is evidence of association b etween infection with Epstein-Barr virus (EBV) a...

Ngày tải lên: 11/08/2014, 00:22

... II inhibitor, which induces apoptosis via the intrinsic pathway[46,47]. TRAIL is a member of the TNF ligand family, which induces apopto- sis through activating the death receptors (reviewed in [48]). ... Camptothecin effectively induces apoptosis in cells in the S phase of the cell cycle. This increased susceptibility to camptothecin-induced apoptosis in the ACH.30.1 cell lin...

Ngày tải lên: 13/08/2014, 05:22

... Miyoshi I, Kubonishi I, Yoshimoto S, Akagi T, Ohtsuki Y, Shiraishi Y, Nagata K, Hinuma Y: Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human ... 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo. J Virol 2006, 80(7):3469-3476. 15. Kiyokawa T, Seiki M, Iwashita S, Imagawa K, Shimizu F, Y...

Ngày tải lên: 13/08/2014, 06:20

... incompletely defined in the virus life cycle or HTLV-1 pathogenesis. Proviral clones of the virus with pX ORF-II mutations diminish the ability of the virus to maintain viral loads in vivo. Exogenous ... carriers. Using molecular clones of HTLV-1 with selective muta- tions of ORF I and II, we have tested the requirement of p12 I and p13 II /p30 II in the e...

Ngày tải lên: 13/08/2014, 13:20

... sequence identity limitation will be suitable, while partial CP without limitation of sequence identity in the definition may help sci- entists to discover novel functional relationships among ... relationships Wei-Cheng Lo and Ping-Chiang Lyu Address: Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan. Correspondence: Ping-Chia...

Ngày tải lên: 14/08/2014, 08:20

... proliferation of infected cells and also inhibit apoptosis by their pleiotropic actions. Since the HTLV -I provirus is randomly integrated into the host genome, the identification of integration ... around 1977, and human T-cell leukemia virus type 1 (HTLV -I) was subsequently identified in 1980. In the 25 years since the discovery of HTLV -I, HTLV -I infection...

Ngày tải lên: 13/08/2014, 09:21

... published information is available on the use of anakinra in pregnancy. Therefore, information is insufficient to evaluate the safety of these medications in pregnancy. Discussion As indicated by ... to the evaluation of the wide variety of medications that are used to treat a specific disease during pregnancy. Second, the objectives of the study are not limited to estim...

Ngày tải lên: 09/08/2014, 08:22

... mean ± standard deviation (n = 3). Figure 6 YC-1 mediated inhibition of hypoxic induction of P4H in meniscus cell aggregatesYC-1 mediated inhibition of hypoxic induction of P4H in meniscus cell ... Distribution of type I, II, III and V in the pepsin sol- ubilized collagens in bovine menisci. Connect Tissue Res 1987, 16:343-356. 19. Kambic HE, McDevitt CA: Spatial organizatio...

Ngày tải lên: 09/08/2014, 10:20

... Plastid targeting signals are typically rich in serines and threonines and low in acidic and basic amino acids and about 45–70 amino acids long. Usually they show only little homology. The predictions ... product it was digested with BglII and AflIII restriction enzymes, AflIII cuts in the 3¢ UTR of the cDNA. The digested fragment was ligated to the com- patible sites of...

Ngày tải lên: 08/03/2014, 23:20

... HBXIP and inhibits apoptosis. The mechanism of the inhibition is mediated by binding of the survivin-HBXIP to Apaf1 and pre- venting the activation of procaspase 9 [26]. Thus, HBXIP has an important ... levels within 4 h following inhibition of protein synthesis by cycloheximide. We next wanted to examine whether the presence of HBXIP binding protein fragment of the...

Ngày tải lên: 23/03/2014, 15:21