Báo cáo y học: "Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells" pot
Báo cáo y học: "Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells" pot
... This effect was specifically due to the action of CytB on Glut-1 and not to an indirect cyto- chalasin effect on microfilaments: Treatment of Jurkat cells with the related cytochalasin D (CytD) ... report concluded that Glut-1 cannot serve as a receptor for HTLV-1 on CD4 T cells: This was based mainly on their inability to detect Glut-1 on this lymphocyte subset us...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Distinctive receptor binding properties of the surface glycoprotein of a natural Feline Leukemia Virus isolate with unusual disease spectrum" pps
... impli- cate the VRB-containing substitution as the major deter- minant of binding phenotype, but also indicate a contribution of the VRA domain. Specifically, the substi- tution of both VRA and VRB ... 3 of 17 test this hypothesis, and to determine which of the func- tional domains confers the binding phenotype, computa- tional modeling was first performed t o examine th...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo khoa học: Mapping the binding domains of the aIIb subunit A study performed on the activated form of the platelet integrin aIIbb3 pot
... that all the experiments in this study were carried out on activated platelets and con- sequently on the activated form of this integrin receptor. We hypothesize that RAD and RAE adhesive motifs, ... suggest that the a IIb 313–332 region is important, not only for fibrinogen binding but also for platelet activation. The rationale of this study was based on the assumption t...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo y học: " Cellular receptor binding and entry of human papillomavirus" pdf
... cause a tran- sition in the virion to the latter, which might initiate internalization and uncoating [17]. Day et al later on demonstrated this model in details via a study on neutralization of HPV ... later studies reported that deletion of this region did not affect the interaction of HPV-33 VLPs with heparin [20], and the interaction was strictly dependent on an intact oute...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: " The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro" doc
... 7:40 http://www.retrovirology.com/content/7/1/40 Page 5 of 7 onstrated that HuR may undergo post-translational phos- phorylation at S202 and/ or S242 [28,29]. Therefore, one cannot rule out the possibility that Lemay et al ... illu- minates some of the potential pitfalls associated with such approaches, and highlights the urgent need to carry out stringent biophysical validation of a...
Ngày tải lên: 12/08/2014, 23:23
Báo cáo y học: " PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line" ppsx
... inducing activity in CTLL-2 cells, but the activity is much less than that of Tax1. Both Tax2B and Tax2B+C are completely devoid of such activity, further indicating that Tax2B does not have IL-2-independent ... citation purposes) domain-containing genes in human. Thus, it is important to consider such proteins as candidates to mediate Tax1 activity in HTLV-1- infected T- cells. We re...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Circulating retinol binding protein 4 in critically ill patients before specific treatment: prognostic impact and correlation with organ function, metabolism and inflammation" pot
... nonpulmonary), and they were closely related to liver and kidney function. The dysregulation of serum RBP4 in ICU patients was not associated with preexisting diabetes or obesity, but might contribute ... hospital, patients were prospectively enrolled at the time of ICU admission. Patients who were expected to stay <72 hours at the ICU (e.g., postinterventional observation, acute i...
Ngày tải lên: 13/08/2014, 21:21
Báo cáo y học: " support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation" pot
... cluster types are units of evolution, in th e sense that they are domains of preserved synteny, as observed in yeast [8-11]. Consid- eration of rates of synteny preservation needs to control for ... 1111100000. This has only one transition (between 1 and 0). By contrast, the less structured organization 0110010101 has seven state changes. The number of transitions between states...
Ngày tải lên: 09/08/2014, 22:24
Báo cáo y học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" ppsx
... effect on the outcomes, it is logical that (C) the pres- ence of the conditions is expected to be positively related to the outcomes of the implementation: Hypothesis C: a positive relation exists ... way that it actually contributed to a higher level of improve- ment. Hypothesis D: a positive relation exists between perceived and actual outcomes. Methods Study population The total...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB" doc
... out the planning and conduct of the study, data collection and manuscript preparation. ALS, AIC and TSB took part in the conduct of study, data collection and interpretation. DB and ASB participated ... Sterling TR, ATS (American Thoracic Society) Hepatotoxicity of Antituberculosis Therapy Subcommittee: An official ATS statement: hepatotoxicity of antituberculosis therapy. A...
Ngày tải lên: 11/08/2014, 08:21