Báo cáo y học: " In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate" pdf

... HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate Andrea Savarino* Address: Department of Infectious, Parasitic and Immune-mediated Diseases, ... BASTET: Bases for Assessment and Evaluation of Eradi- cation Strategies), and by the Italian Ministry of Research and University, Rome, Italy (FIRB grant: Costruzione...

Ngày tải lên: 13/08/2014, 09:20

... There was no invalid test result among all 430 samples. Discussion At an early undifferentiated stage of disease diagnosing RA can be difficult and challenging as clinical manifesta- tion may appear ... development of the assay, the amount of gold- conjugated anti-human IgG, the number of conjugated colloidal gold particles, and the amount of anti-human IgG were empirically titrat...

Ngày tải lên: 12/08/2014, 14:22

... Otsuka K, Murakami S, Hotta N, Yamanaka G, Kubo Y, Yamanaka T, Shinagawa M, Nunoda S, Nishimura Y, Shibata K, Saitoh H, Nishinaga M, Ishine M, Wada T, Okumiya K, Matsubayashi K, Yano S, Ichihara ... Sheedy PF 2nd, Peyser PA: Aortic pulse wave velocity is associated with the presence and quantity of coronary artery calcium: a community-based study. Hypertension 2006, 47:174-179. 7. Mats...

Ngày tải lên: 13/08/2014, 16:21

... PJ, Kumar BV, Nayana RS, Mohan MS, Bolligarla R, Das SK, Bhanu MU, Kondapi AK, Ravikumar M: Design, synthesis, and discovery of novel non- peptide inhibitor of Caspase-3 using ligand based and structure ... Taiwan. 3 Chemical Analysis Division, Institute of Nuclear Energy Research, 1000, Wunhua Rd., Longtan Township, Taoyuan County, 32546, Taiwan. 4 Division of Genetics and Metaboli...

Ngày tải lên: 10/08/2014, 05:21

... allophycocyanins and phycocyanins, HPLC separation allowed a quantitative estimation of the relative amount of each protein component from the area underlying each peak. This was facilitated by the ... phycobilisomes before and after illumination reve aled the d isappearance of the b-phycocyanin already after 1 h of illumination (Fig. 4). In contrast, SDS/PAGE analysis of the tota...

Ngày tải lên: 08/03/2014, 16:20

... Mitsuuchi. Y. , Toda, K., Miyahara, K., Yokoyama, Y. , Nakao, K., Hosoda, K., Y amamoto, Y. , I mura, H. & Shizuta, Y. (1990) Cloning of cDNA and genomic DNA for human c ytochrome P-45011 beta. FEBS ... cardiovascular or endocrine diseases, Fig.3.Assessmentof11b-h ydroxylase a ctivity and determination of 11b-hydroxylase capacity. (A) Assessmentof11b-hydroxylase activity of...

Ngày tải lên: 24/03/2014, 03:21

... years at entry, female gender, non- African American ethnicity, history of transfusion, lower level of albumin and elevated level of AFP. Longitudinal observation of ALT changes in 178 patients ... univariate and multivariate analysis. Both Chi-square test for trend and Kaplan-Meier survival analysis were used for analyzing the correlation of dynamic ALT follow-up with developmen...

Ngày tải lên: 08/08/2014, 18:20

... 40:1917-1927. 3. Fujisawa K, Asahara H, Okamoto K, Aono H, Hasunuma T, Kobata T, Iwakura Y, Yonehara S, Sumida T, Nishioka K: Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax trans- genic ... Lubbe PA van der, Cauli A, Daha MR, Smeets TJ, Kluin PM, Meinders AE, Yanni G, Panayi GS, Breedveld FC: Reduction of synovial inflammation after anti-CD4 monoclonal antibody...

Ngày tải lên: 09/08/2014, 01:22

... Epidemiology and Community Studies, SMBD Jewish General Hospital, Montreal, Canada 3 Joint Department of Epidemiology and Biostatistics, and Occupational Health, McGill University, Montreal, Canada 4 Department ... physician specialty in the medical database; and prior dispensation of gastroprotec- tive agents in the prescription database. Prescribed daily dosage of the COX-2 inhibitor...

Ngày tải lên: 09/08/2014, 06:22

... disease modification by affecting both the growth-factor triggered activation of fibroblasts and the accumulation of T lymphocytes. The significance of this research for understanding the pathogenesis of RA (and ... directly to the pathogenesis of synovial inflammation and joint destruction has seen a ‘revival’ over the last couple of years [6,7]. This is mainly due to the obser...

Ngày tải lên: 09/08/2014, 06:22