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Báo cáo y học: " No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms" doc

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Báo cáo y học: " No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms" doc

... for citation purposes)RetrovirologyOpen AccessResearch No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasmsThomas Burmeister*1, ... T-cell (50) Early T-cell lymphoblastic 11Cortical (thymic) T-cell lymphoblastic31 34 (17–63) Mature T-cell lymphoblastic 8 Mature T-cell (31) T-prolymphocytic 16Sézary syndrome and Mycosis fungoides5Ki-1 ... draw-gram was used with the default parameters to construct aphylogenetic tree from the aligned sequences.ImmunophenotypingImmunophenotyping by FACS analysis was done essen-tially by standard methods...
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Báo cáo y học: "Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study" potx

... 0.001).ALI/ARDS timelines and outcomesA diagnosis of ALI/ARDS was made after a median of 1 day(interquartile range 0 to 4 days) from the day of clinical insult in all patients (Figure 3a), and was not statistically ... conditions. Screening for ALI/ARDSdiagnosis was continued for 7 days unless another clinicalinsult developed, in which case follow-up was continued for atotal of 14 days. When a diagnosis of ALI was ... clinical conditions previously linked tolung injury, both inside and outside the intensive care unit. Patients were followed prospectively for outcomes, includingthe diagnosis of acute lung injury...
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Báo cáo y học: "Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia" docx

... disease using a small number of samples, especially in the case of consanguineous family. Here, we performedexome sequencing in combination with runs of homozyg-osity (ROH) analysis in order ... 592 In run -of- homozygosity regions 35 (in 33 genes)The filtering was performed using the list ed criteria in descending order.Table 2 List of novel and functional variants in run -of- homozygosity ... analysis of mitochondrial DNA deletions in the brains of patients with bipolar disorder and schizophrenia. Int JNeuropsychopharmacol 2005, 8:515-522.33. The Database of Genotypes and Phenotypes...
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Báo cáo y học: "Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins" pdf

... and also distinguishes between synon-ymous and non-synonymous sites. In a sequence having no evolutionary constraints, the ratio of non-synon-ymous and synonymous sites that are fixed between ... Only confirmed polymorphisms wereused in the subsequent analyses. Details of synonymous and non-synonymous SNPs in S. cerevisiae and S. para-doxus strains are de scribed per protein-coding ... protein-codingregion may be classified as synonymous SNPs or non-synonymous SNPs, depending on whether t he encodedamino acid is altered in the alternative DNA sequencevariants. Non-synonymous SNPs in coding...
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Báo cáo y học: " Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective" pot

... Society of Intensive Care Medicine; Society of Critical CareMedicine; Society of Hospital Medicine; Surgical Infection Society; WorldFederation of Societies of Intensive and Critical Care Medicine: ... line with theline of null effect (’cross-over’ point) occurred for age at62 years and for control-arm mortality at 44%.Complications of therapyThe complications of therapy were secondary infections,gastro-intestinal ... study [8] was‘somewhat disappointing’ [12] undoubtedly reflects thishistory of therapeutic uncertainty. Current guidelinesadvocate a role for intravenous hydrocortisone in adult septic shock patients...
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot

... adipocytic/fat-storing mesenchymal cells and loss of thymocytes with advancing age lead to a novel con-ceptual point of view concerning the understanding of the process of thymic physiology in ... 1. Increase of fat-storing cells within the murine thymus with advancing age. Photomicrographs of thymus paraffin sections (5μm) derived from mice of distinct ages were stained with hematoxylin ... thymus and total thymocytes with age (Figure 5). Using immunohistochemical method, thymocytes and thymic stromal cells stained posi-tively for CCL4 and CCL5 (Figure 6). Interestingly, in the...
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Báo cáo y học: " laboratory driving simulation for assessment of driving behavior in adults with ADHD: a controlled study" docx

... data in the study and takeresponsibility for the integrity of the data and the accuracy of the data analysis. I am also responsible for editing thefinal draft.RF: Involved in the writing of ... the design and analysis of the driving data.CBS: Involved in the writing of the manuscript includingreading the literature and integrating the literature with the findings and writing the discussion.MA: ... includingreading the literature and integrating the literature with the findings and writing the discussion.SVF: Involved in the writing of the manuscript includingreading the literature and...
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Báo cáo y học: " Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis" docx

... aminoethylcarbazole staining (red) for active caspase-3 (hematoxylin-counterstained) before (a) and after (b) treatment and diaminobenzidine staining (brown) for TUNEL (hematoxylin-counterstained) ... were thenstained with mouse IgG1 allophycocyanine-conjugated anti-CD3 antibody (555335; BD Biosciences) and incubated with Annexin V and 7-amino-actinomycin D (7-AAD) as specified bythe manufacturer ... evaluated synovial apoptosisusing the TUNEL (terminal deoxynucleotidyl transferase-medi-ated dUTP-biotin nick end-labeling) technique and staining for the active form of caspase-3 in 2% formaldehyde-fixed...
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Báo cáo y học: "Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis" pdf

... were thenstained with mouse IgG1 allophycocyanine-conjugated anti-CD3 antibody (555335; BD Biosciences) and incubated with Annexin V and 7-amino-actinomycin D (7-AAD) as specified bythe manufacturer ... evaluated synovial apoptosisusing the TUNEL (terminal deoxynucleotidyl transferase-medi-ated dUTP-biotin nick end-labeling) technique and staining for the active form of caspase-3 in 2% formaldehyde-fixed ... by Bonferroni correction for multiple comparisons of paired samples for the synovial biopsy data. In vitro data wereanalyzed by one-way analysis of variance followed by Tukeypost hoc analysis...
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Báo cáo y học: "A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data" pot

... sample with relatively greaterconsistency. These results motivate the utility of infer-ring both baseline ploidy and normal contaminationwithin an integrated framework since the ploidy s tatus and ... Turpaz Y: Ploidy status and copynumber aberrations in primary glioblastomas defined by integratedanalysis of allelic ratios, signal ratios and loss of heterozygosity using500K SNP Mapping Arrays. ... is very similar and in the absence of externalkaryotype information, or prior knowledge of thetumorploidyorthelevelof normal DNA contamina-tion, each of these interpretations is entirely plausible.Figure...
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