Báo cáo y học: " Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV" pot

... of 15 (page number not for citation purposes) Retrovirology Open Access Research Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung ... wild-type strains of JSRV from around the world. The histologic appearance of the majority of lung tumors in sheep infected with JSRV and...

Ngày tải lên: 13/08/2014, 09:20

... significant increase in affinity for duplex DNA [12]. We investigated the junction specificity of MpRuvA by analysing its binding to a Y- shaped junction and to linear duplex DNA. Like the E. coli protein, MpRuvA ... by the E. coli RuvABC resolvasome complex requires the binding of RuvA to one face of the junction and RuvC to the other [8,9]. Complexes formed by the...

Ngày tải lên: 17/03/2014, 17:20

... 63–97; indi- catedbyarrow)isindarkblue.Thecatalyticacids(seeAabove) are colored in yellow. M52 AMY2 (M53 AMY1 )andW83 TAA are in red (indicated by arrow). Y5 1 AMY2 and Y8 2 TAA are in orange. Other binding ... though the rates of hydrolysis of the oligosaccharide substrates greatly decreased, the binding mode was most probably controlled by the outermost high- affinity...

Ngày tải lên: 31/03/2014, 08:20

... 4 of 4 infiltrates surrounding the vascular structures and dis- persed within the adipose tissue (Figure 2). The infiltrate was comprised of small lymphocytes with clumped chromatin, indistinct ... lymphocytes being CD3 (+) T-cells. Together, the flow cytometry of the peripheral blood and immunohistoc hemistry of the pericardial tissue were consistent with pericardial...

Ngày tải lên: 11/08/2014, 03:21

... lymphocytes being CD3 (+) T-cells. Together, the flow cytometry of the peripheral blood and immunohistoc hemistry of the pericardial tissue were consistent with pericardial involvement by CLL. The ... biopsy (Hematoxylin and eosin stain). Note the focal lymphocytic infiltrate in the pericardial tissue removed at the time of the subxiphoid pericardial window. Figure...

Ngày tải lên: 11/08/2014, 07:20

... a therapeutic target in AKI. Modulation of these cytokines may reduce the degree of kidney injury itself, as well as the deleterious effects of kidney injury on other end organs, including the ... is the surgery and bypass itself. Thus, the tim- ing of the insult is clear. Based on our animal studies, we hypothesized that levels of proinflammatory cytokines would incre...

Ngày tải lên: 13/08/2014, 16:21

... 2002 understanding of the function and organization of the enzyme complex, the analysis of mutant a lleles of the ge nes involved in the biosynthetic pathway c an certainly provide valuable information. In ... required for the association of the different enzyme monomers or for their interaction with other membrane proteins. The observed in vitro activation...

Ngày tải lên: 22/02/2014, 04:20

... concentrations were determined by the Bradford assay using BSA as the standard. The following purified proteins were kindly provided by colleagues: the MBP fusion protein of the NBD of the lactococcal ... binding and transport are located within the transmembrane domains in P-gp and MRP [22–30]. Interestingly, however, two studies point to the binding of an alloc...

Ngày tải lên: 17/03/2014, 23:20

... cultures Anaphase-promoting complex subunit 8 Cyclin-dependent kinase inhibitor 3 Kinesin-like protein 1 Selenium binding protein 2 Bone morphogenetic protein 4 Cytoskeleton associated protein 2 Kinesin-related protein ... for driving the arthritogenic activities of IL-1. These products include the primary cytokines, chemokines, synthetic and proteolytic proteins associated...

Ngày tải lên: 09/08/2014, 08:23

... manuscript, the HLA typing and statistics, and also contributed to the writing of the last version of this manuscript. CLL reviewed the manuscript, the HLA typing and contributed to the writing of the ... version of this work. MA participated in the study design, the recruitment and eval- uation of patients, and in the writing of the manuscript. CS per- f...

Ngày tải lên: 09/08/2014, 08:23