Báo cáo y học: " Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks" potx

... not for citation purposes) Reduced susceptibility of EU CD4 T cells to infection by pseudotyped HIV-1Figure 1 Reduced susceptibility of EU CD4 T cells to infection by pseudotyped HIV-1. CD4 T cells ... suggesting that the mechanisms of resist- ance in these subjects do not depend on exposure to the virus but rather might be linked to constitutive factors....

Ngày tải lên: 13/08/2014, 09:20

... of statistical tests [26]. If the result is still <0.05, then the result is clearly statistically significant. Using the Bonferroni approach for any analysis involving individual resistance codons, ... National Institutes of Health, the Pediatric/Perinatal HIV Clinical Tri- als Network of the National Institute of Child Health and Human Development, National Institutes of Health,...

Ngày tải lên: 10/08/2014, 05:20

... binding, leading to PERV-A entry. This, together with recent studies on the determinants in PERV Env for binding and entry [37,38] contribute to better understanding of PERV-receptor interactions. ... ATT GGA TGA AGA TG Q1 TCA AGG TGT CTC CCA TCA ATT TC Q2 CGT CAA CAC CCA AAA GAA TGT G Q3 TCG AGG CCC TGT AAT TGG AA Q4 CCC TCC AAT GGA TCC TCG TT ZF TAC CTG GTT GAT CCT GCC AGT A ZR T...

Ngày tải lên: 13/08/2014, 05:22

... MJDvT contributed to the interpretation of data. CMJ-vZ contributed to the acquisition, analysis and interpretation of the data. REMT contributed to the interpretation of the data. TWJH contributed ... cit- rullinated autoantigens. The present study convincingly dem- onstrated that the ability to mount a recall response against TT remained intact after immunoablative therapy. The la...

Ngày tải lên: 09/08/2014, 10:21

... probably due to heavy glycosylation of multiple synovial proteins, and the smearing limited our ability to excise discrete bands for mass spectrometry analysis. Autoantibody targeting of citrullinated ... citrullinated proteins generated in inflamed joint tissue but also with citrullinated filaggrin, a protein expressed in stratified epithelium but not in joints [4,6]. It is int...

Ngày tải lên: 09/08/2014, 13:22

... nature of the submitted tissue, is reported. Introduction Maffucci syndrome is a rare clinical entity (approxi- mately 200 cases have b een reported in the medical lit- erature) [1]. It consists of ... under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses /by/ 2.0), which permits unrestricted use, distribution, and reproductio n in any medi...

Ngày tải lên: 10/08/2014, 23:21

... re considered to have illness that is resistant to treatment [3]. In this context, antipsychotic combination treat- ment, also called antipsychotic polypharmacy, has been frequently used in clinical practice. ... patients receiving monotherapy. These findings are consistent with a study showing that patients who received antipsychotic combinations exhibited more positive and excit...

Ngày tải lên: 11/08/2014, 16:23

... estimate is to take into account that each positive signal could arise from more than one cell containing the provirus and their distribution into each well is essentially random. In this case the ... related to the total number of cells N by a con- version factor a. Thus: The cultures were heterogeneous containing both puro- mycin resistant and sensitive cells. The to...

Ngày tải lên: 13/08/2014, 09:20

... University of Washington Institute for Social and Policy Studies, Yale University International Criminal Court International Peace Research Institute Oslo (PRIO) International Rescue Committee Iraq ... practice. 'Serendipity', or the act of accidentally discovering some- thing fortunate, is the other side to the coin. Catrien Bijleveld, a criminologist with VU University Amste...

Ngày tải lên: 13/08/2014, 13:21

... ADAR activity: inverted Alu elements would attract ADAR to harm- less intronic sites and thereby titrate the activity of the enzyme away from important targets of selective editing, perhaps thereby ... Could they therefore contribute to chromatin domains that might influence transcriptional activity? If so, could this be related to editing? This possibility is supported by the r...

Ngày tải lên: 14/08/2014, 14:21