Báo cáo y học: " The conserved dileucine- and tyrosine-based motifs in MLV and MPMV envelope glycoproteins are both important to regulate a common Env intracellular trafficking" doc

... endosomes and is mainly local- ized in the TGN at steady state [15], internalized cyanin3- conjugated transferrin that reveals the general early and recycling endosomal pathway and Lamp1, a marker ... citation purposes) Retrovirology Open Access Research The conserved dileucine- and tyrosine-based motifs in MLV and MPMV envelope glycoproteins are both...

Ngày tải lên: 13/08/2014, 09:20

... pathways includ- ing the intracellular signaling adaptor protein IPS-1 and the kinase PKR. Defective innate immunity may predispose to acute exacerbations of COPD that are characterized by acutely worsening ... that is char- acterized by increased inflammatory cytokine expression and cell infiltration into the lungs, non-cardiogenic pul- monary edema, and diffuse alveolar da...

Ngày tải lên: 11/08/2014, 03:20

... monitoring and ventilator devices that capture physiological and ventilation data. These data were validated by nursing or respiratory therapy staff on at least an hourly basis by examining the ... ICU-acquired hyponatraemia and hypernatraemia varies according to patient characteris- tics. • ICU-acquired hyponatraemia and hypernatraemia are associated with increased risk of ho...

Ngày tải lên: 25/10/2012, 10:31

... folding mechanism two approaches are most commonly used: (a) characterization of the intermediates to understand the structural changes involved in each transition, and (b) analysis of the kinetic ... Debasish Bhattacharyya 2 and Chanchal Das Gupta 1 1 Department of Biophysics, Molecular Biology and Genetics, University of Calcutta, Kolkata, India; 2 Indian Institute of Chem...

Ngày tải lên: 08/03/2014, 23:20

... 206–214. 25. Kawamoto, T., Mitsuuchi. Y. , Toda, K., Miyahara, K., Yokoyama, Y. , Nakao, K., Hosoda, K., Y amamoto, Y. , I mura, H. & Shizuta, Y. (1990) Cloning of cDNA and genomic DNA for human c ytochrome ... Ichikawa, Y. , Yokoyama, Y. , Sumimoto , H., Toda, K., Miyahara, K., Kuribayashi, I. & Nakao, K., et al. (1990) Cloning and expression of a cDNA for human cytochr...

Ngày tải lên: 24/03/2014, 03:21

... at all", leaving a final dataset of 162 inci- dent ratings from 162 participants. Data were analyzed using SAS ® v 8.2 software (SAS Insti- tute, Cary, NC). A factor analysis using maximum ... generalizing our findings either to a more trauma- exposed population or to the general population. Our sample was selected according to the needs of a parent Table 3: Factor loa...

Ngày tải lên: 08/08/2014, 20:23

... [1]. These autoantibodies differ from anti-DNA antibodies found in the sera of healthy individuals in that they bind to dsDNA with high affinity, they are often cationic in charge and they do ... autoimmune haemolytic anaemia, lymphopaenia, thrombocytopaenia, and homogeneous antinuclear antibodies characterized as anti-DNA antibodies. At the time of splenectomy the patient...

Ngày tải lên: 09/08/2014, 01:21

... by adding the points for cartilage damage and pannus formation. Total arthritis score (Score) was calculated by adding scores for inflammatory changes and joint destruction, giving a maximal ... increased hyperplasia and infiltration of the synovial membrane, as well as increased articular damage in those animals (Fig. 2b–d). In summary, this indicates a marked exacerbation...

Ngày tải lên: 09/08/2014, 06:22

... recent advances in anti-inflammatory therapy, rheumatoid arthritis (RA) patients continue to rate pain as a priority. The etiology of RA pain is likely multifactorial, including both inflammatory and ... consider both inflamma- tory and non-inflammatory factors when evaluating pain in research settings and in the clinic. Future studies are needed to better understa...

Ngày tải lên: 09/08/2014, 14:22

... Nazarians-Armavil A, Deshpande A, Joe S, Datsenko KA, Yamamoto N, Andrews BJ, Boone C, Ding H, et al.: eSGA: E. coli synthetic genetic array analysis. Nat Methods 2008, 5:789-795. 27. Typas ... Weitzman MD, Kuhen KL, Bandyopadhyay S, Ideker T, Orth AP, Miraglia LJ, Bushman FD, Young JA, Chanda SK: Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replicatio...

Ngày tải lên: 09/08/2014, 20:21