Báo cáo y học: " Role of common human TRIM5α variants in HIV-1 disease progression" ppsx
Báo cáo y học: " Role of common human TRIM5α variants in HIV-1 disease progression" ppsx
... and intron-exon
Association of human TRIM5α haplotypes with HIV-1 disease progression in vivoFigure 3
Association of human TRIM5α haplotypes with HIV-1 disease progression in vivo. Panel A, Inferred ... (Gibco-Invitro-
Restriction of HIV-1 by common human TRIM5α variantsFigure 2
Restriction of HIV-1 by common human TRIM5α var-
iants. HeLa cells were...
Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... pathway involved in acid secretion induced by
low taurine concentrations may predominantly involve
in cholinergic neurons. Both TTX and atropine comple-
tely inhibited the acid secretion induced by ... he A type of GABA receptors,
which are mainly located on cholinergic neurons though
cAMP pathway and partially on nonneuronal cells in
the stomach. In light of the findings of pre...
Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... Induction of osteoarthritis by 2-methoxyestradiol
demonstrates the importance of HIF-1 in maintaining the
integrity of hypoxic articular cartilage. Stabilization of HIF-1 by
dimethyloxaloylglycine, ... and dimethyloxaloylglycineEffects of 2-methoxyestradiol and dimethyloxaloylglycine. Effects on synovial tissue, levels of hypoxia-inducible factor (HIF) 1α and viability of
cho...
Báo cáo y học: " Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation" docx
... blocking only the NK
1
receptor
is most likely insufficient, as most of the effects of tachy-
kinins in the airways are mediated by more than one tach-
ykinin receptor. Indeed, not only the ... four
point scale 0) none or very weak staining; 1) weak stain-
ing; 2) moderate staining; 3) intense staining.
Measurement of chemokines
Using commercially available ELISA kits (R&D System...
Báo cáo y học: " Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma" potx
... key role in orchestrating
inflammatory and structural changes of the airway in
asthma by recruiting, activating and promoting inflam-
matory cells into the airway [38-40]. In addition to
cytokines, ... mortality [29]. These studies suggest a role for LPA
receptors in linking lung injury in the murine bleomycin
model of pulmonary fibrosis.
Asthma is a chronic inflammatory di...
Báo cáo y học: " Role of ADAM and ADAMTS metalloproteinases in airway diseases" pot
... contributing in this
way to the control of inflammation which is a hallmark of
asthma pathology. Disintegrin domain might also act in
concert with cystein-rich region to interfere with pro-
inflammatory ... specifically
the "functional binding edge" is interacting with the cata-
lytic domain of the ADAM proteinase [32]. The interac-
tion of the catalytic site-bound Zinc...
Báo cáo y học: " Role of the Fas/FasL Pathway in HIV or SIV Disease" ppsx
... HIV/AIDS.
Significance of indirect cell killing for HIV vaccine/
therapeutics design
Knowing the role for uninfected bystander cell killing in
disease has not resolved the challenge of applying this
information ... Upregulation of Fas ligand expression by human immu-
nodeficiency virus in human macrophages mediates apopto-
sis of uninfected T lymphocytes. J Virol 1996, 70:...
Báo cáo y học: " Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses" ppt
... infection by various inhib-
itors of N-linked glycosylation: deoxymannojirimycin
(DMM); castanospermine (CST), swainsonine (Sw),
deoxynojirimycin (DMN), 2-deoxy-D-glucose (2DG) and
tunicamycin ... containing syncytia in response to focal areas of
virus infected cells. Plates were fixed and stained 3 days
later and examined for plaques of syncytia.
Syncytium formation and inhibitors o...
Báo cáo y học: "Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study" pot
... supplementary infusion
of 0.067 U/minute AVP was more effective in restoring
MAP and reducing norepinephrine requirements than
the recommended low dose of 0.033 U/minute.
Interestingly, infusion of the ... the
Department of Anesthesiology and Intensive Care at the University of
Muenster (Muenster, Germany), for expert technical assistance during the
study. This work was supported...
Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells pot
... be
activated independently of increases in [Ca
2+
]
i
, probably via
receptor coupling of this enzyme [36]. Though TG stimu-
lated the induction of expression of mRNA of four PLA
2
isotypes, only three of ... mRNA of four PLA
2
isotypes
(type IB, type V, type IV and type VI). Interestingly,
addition of TG stimulated the induction of the four PLA
2
isotypes in Jurkat T-ce...
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