Báo cáo y học: " Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C Tat protein" docx

... Central Page 1 of 20 (page number not for citation purposes) Retrovirology Open Access Research Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization ... GFP microscopy: Tat protein B. SEAP assay: Tat protein No Tat C -Tat B -Tat 1.1% 1.7% 30.1% 39.2% 18.7% 24.6% C. GFP flow cytometry: Tat prote...

Ngày tải lên: 13/08/2014, 09:20

... T lymphocyte and macrophage populations [16]. Moreover, the enzyme responsible for the final and rate-limiting hydroxylation step in the synthesis of active vitamin D, 25(OH)D-1-a- hydroxylase, ... therapy in inflammatory disease states. Abbreviations 1,25(OH) 2 D: 1,25-dihydroxyvitamin D; 25(OH)D: 25- hydroxyvitamin D; CRP: C-reactive protein; DXA: dual- energy x-ray absorptiometry; Hi...

Ngày tải lên: 11/08/2014, 08:22

... activating cofactors. Alternatively, inhibition could be explained by diluting of these cofactors by an excess of nonDNA-bound SRF. This would be the more likely mechanism of the inhibition observed by ... extracts were analyzed by Western blotting using an antimyc antibody. The migration of the fusion proteins containing the myc epitope: human (HsSRF-myc), D. melanogaster (DmSRF-myc)...

Ngày tải lên: 22/02/2014, 07:20

... cell growth. Transcription of the Scylla and Charybdis genes is induced by hypoxia via the hypoxia-inducible transcription factor HIF. The same induction by HIF and downstream effects on TSC1/TSC2 ... intersec- tion of two important and evolutionarily conserved signaling pathways, the hypoxia-induced and the insulin pathway. Turning from the control of size to the control of...

Ngày tải lên: 14/08/2014, 14:21

... infections and primary bacter- aemias); ICU length of stay; days of mechanical ventilation and incidence of severe hypoglycaemia defined as number of patients with at least one episode of blood ... therapy is equally effica- cious in both medical and surgical patients [12]. Therefore, we conducted a randomised clinical trial to assess the efficacy and safety of intensive i...

Ngày tải lên: 25/10/2012, 10:35

... primary lower limb lymphedema, by discussing the overall physical and mental impact of primary lymphedema through the use of metric tools of health related qual- ity of life domains and highlighting ... malignancy [1]. The most common cause of secondary lymphedema worldwide is filariasis, an infestation of the lymph nodes by the parasite Wuchereria bancrofti [2]. Primar...

Ngày tải lên: 25/10/2012, 11:40

... c-chain, leading to tyrosine phosphorylation and activation of syk and PLCc2 [13,14]. Following activation of GpVI by convulxin, several adapter molecules are tyrosine phosphorylated and/ or recruited ... by Rho kinase and the other by the Ca 2+ -dependent activation of MLC kinase. These two pathways could be activated independ- ently of each other, depending on the type and...

Ngày tải lên: 21/02/2014, 01:21

... reactivation of encysted bradyzoites into actively replicating and cytolytic tachyzoites can trigger a disease with severe clinical syndromes leading in many cases to the death of the patients. ... eukaryotic RNA-processing proteins and type D retroviral polyproteins. Trends Biochem. Sci. 24, 342–344. 21. Burd, C. G. & Dreyfuss, G. (1994) Conserved structures and diversity of...

Ngày tải lên: 08/03/2014, 22:20

... Engineering and Biotechnology and funds from Department of Science and Technology, Government of India. We thank Prof. S. Assmann for critical reading of the manuscript and constructive suggestions and ... effects of EGTA and W7 on low temperature- and salinity-mediated expres- sion of PsCCaMK indicate that their responses are medi- ated by different signaling path...

Ngày tải lên: 18/03/2014, 01:20

... University Bloomberg School of Public Health, Baltimore, Maryland, USA The presence of extra N- and C- terminal residues can play a major role in the stability, solubility and yield of recombi- nant ... proper folding or of increased solubility of the protein of interest. We propose that the success of fusion protein systems should be ascertained only once the protein of i...

Ngày tải lên: 23/03/2014, 21:20