... or by homology to LTR_STRUC- identified elements. ClustalX [13] was used to build a multiple alignment of the RT domain of these 425 elements together with the RT domains of 16 previously described ... (bootstrap value of 99; Figure 3). The age of each subfamily was estimated by calculating the average of the pairwise distances Insertion of a member of the CERV 3...
Ngày tải lên: 14/08/2014, 16:21
... conducted the ELISA experiments and participated in the design of the study and analysis of the data. FC participated in the design of the study and in the anal- ysis of data and helped to draft the ... revision of the study. AS partic- ipated in the analysis and interpretation of data and helped to draft the manuscript. RR participated in the design of...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture" doc
... immunity [5]. One of the major problems in accurately determining the infec- tion rate is the difficulty in isolating, by traditional culture meth- ods, the bacteria from the surface of the prosthetic ... synonyms of Methylo- bacterium extorquens and of Methylobacterium lusitanum as a later subjective synonym of Methylobacterium rhodesianum. J Gen Appl Microbiol 2005, 51...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263–275) epitope: an MHC anchor variant peptide for immune modulation" pot
... key MHC anchor position. The latter quality may add to improved safety of APL therapy. Ideally, the properties of an APL for immunotherapy of RA would blend: affinity for MHC class II binding; ... Some of these MHC β-chain residues are the same as residues that are close to the TCR in the published crystal structure [38]. Other residues might influ- ence the activation ind...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane" pot
... Brown-Forsythe version of the Levene test; labeled in red) in the Kyoto Encyclopedia of Genes and Genomes (KEGG) MAPK signaling pathway. Among the three MAPK family sub-pathways, the classical and the ... performed the KEGG analyses, contributed to the real- time RT-PCR analyses, and participated in the writing of the manuscript. CH analyzed the microarray data, per...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection" ppsx
... IBA, of the gene YJL167W, which encodes the yeast farnesyl pyro- phosphate synthetase Erg20p, the only known molecular tar- get of N-BPs in humans [16]. Interestingly, ALE, which had only a very ... two-way ANOVA of the wild-type strain and the hemizygote mutants DBF4 and ALF1 in the presence and absence of the drug ibandronateGrowth data and two-way ANOVA of the wil...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Identification of functional modules that correlate with phenotypic difference: the influence of network topology" potx
... inputs: the expression profiles of two p henotypes, a list of gene sets, and their topology. Inthisstudy,thegenesetsaretakenfromtheKEGG database [64] as of April 2009: the gene files specify genes ... in the network reduced by genetic buffering effects or by the incompleteness of the topology. TIF measures the effects of pathway topology on the biological function of...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD)" pdf
... effect on other tested protease activities. On the other hand, DCI and E64 were highly inhibitory of the chymotrypsin-like activities as well as cathepsin B, J, and/ or L activities, but they did ... pepstatin A had primarily inhibited the processing events. Functional role of cathepsin D/E in the processing of PPD by XS52 DC To identify the protease(s) inhibited by pepstatin...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "Identification of an effective siRNA target site and functional regulatory elements, within the hepatitis B virus posttranscriptional regulatory element" ppt
... elements The HBV post -transcriptional regulatory element is highly conserved among the mammalian hepadnaviridae [23]. As the sequence of the PRE also encodes the P pro- tein, the conservation may partly ... export pathway utilized by the hepatitis B virus posttranscriptional regulatory element. Virology 1999, 259:299-304. 34. Zang WQ, Fieno AM, Grant RA, Yen TS: Identificati...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: " Identification of a novel linear B-cell epitope in the UL26 and UL26.5 proteins of Duck Enteritis Virus" doc
... the minimal sequence of the epitope defined by mAb 1C8 appeared to be 520 IYYPGE 525 , because any deletion of residues from either end of 520 IYYPGE 525 destroyed the ability of mAb 1C8 to bin ... IYYPGE R S PRPVER PTP YYAPA A P PQLLPP DQRELDS FYSGE S QMDG DHPRGRSGGGDDDEAYYPGE G A PAELPP EPLRSRGGG DDEAYYPGE G A PAELPP DQDEPDA DYPYYPGE ARGA PRGVDS GRDEPDR DFPYYPGE ARPE PRP...
Ngày tải lên: 12/08/2014, 01:21