... injury and inflammation via induction of cytokines, chemokines and modulatory enzymes. Hyaluronan (HA), a negatively charged normally high molecular weight glycosaminoglycan, is ubiquitously dis- tributed ... (Calbiochem Novabiochem, La Jolla, CA). We assessed effects of NAC and DMSO on cell viability by trypan blue exclusion as well as by FACS for annexin. Chemicals and reagents Pu...
Ngày tải lên: 11/08/2014, 08:22
... Institute of Health, U.S .A. ). Statistical analysis All data were presented as the mean ± standard error of the mean (S.E.M.). The data was analyzed by a statistical anal- ysis of variance, a Scheffe's ... Idaigaoka-Hasamamachi-Yufu City- Oita 879-5593, Japan Email: Satoshi Hagiwara* - saku@med.oita-u.ac.jp; Hideo Iwasaka - hiwasaka@med.oita-u.ac.jp; Shigekiyo Matsumoto - SI...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: "Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope" potx
... Human T-cell leukemia virus type 1 envelope-mediated syncytium forma- tion can be activated in resistant Mammalian cell lines by a carboxy-terminal truncation of the envelope cytoplasmic domain. ... 2001, 75:12266-12278. 46. Saha K, Yan H, Nelson JA, Zerhouni-Layachi B: Infection of human and non-human cells by a highly fusogenic primary CD4- independent HIV-1 isolate with a t...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb" doc
... h post-transfection by thin-layer chromatography, quanti- fied on an Instant Imager (Canberra Packard) and expressed either as absolute acetylation values or as a per- centage of the levels of CAT acetylation of ... 6:543–551. 31. Grolleau A, Bowman J, Pradet-Balade B, Puravs E, Hanash S, Garcia- Sanz JA, Beretta L: Global and specific translational control by rapamycin in T cell...
Ngày tải lên: 13/08/2014, 09:20
Báo cáo y học: " DBR1 siRNA inhibition of HIV-1 replication" pptx
... Isolation and characterization of the gene encoding yeast debranching enzyme. Cell 1991, 65:483-492. 5. Vijayraghavan U, Company M, Abelson J: Isolation and character- ization of pre-mRNA splicing ... of an RNA lariat, and demonstrated that the genomic RNA lariat is an unantici- pated intermediate in the life cycle of Ty1 [2]. The location of this branch suggests that it may play a...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo Y học: The porcine trophoblastic interferon-c, secreted by a polarized epithelium, has specific structural and biochemical properties potx
... (Kirkegaard & Perry Laboratories Inc., or Sigma-Aldrich, USA). As a standard, porcine rIFN-c (CIBA-Geigy) was used at a concentration of 10 lgÆmL )1 . Antiviral activity. Antiviral activity was ... Honda, S., Asano, T., Kajio, T., Nakagawa, S., Ikeyama, S. & Ichimori, Y. (1987) Differential purification by immunoaffinity chromatography of two carboxy-terminal portion-deleted de...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: " ISS mapped from ICD-9-CM by a novel freeware versus traditional coding: a comparative study" ppsx
... based on direct AIS coding by expert registrars. Materials and methods We used the database of the Italian Trauma Registry (RITG) and the standard administrative database of hos- pital dischar ... MacIntyre CR, Ackland MJ, Chandraraj EJ: Accuracy of injury coding in Victorian hospital morbidity data. Aust N Z J Public Health 1997, 21:779-83. 17. Wynn A, Wise M, Wright MJ, Rafaat A,...
Ngày tải lên: 13/08/2014, 23:21
Báo cáo y học: " Mode of inhibition of HIV-1 Integrase by a C-terminal " docx
... Bujacz G, Jaskolski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA, Skalka AM: The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of ... conformational change and activation of HIV-1 integrase. J Biol Chem 1997, 272:16196-16205. 26. Yi J, Asante-Appiah E, Skalka AM: Divalent cations stimulate pref- erential recognitio...
Ngày tải lên: 13/08/2014, 09:20
Báo cáo y học: "Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study" pptx
... OA cartilage. Shown are the percentage changes compared with healthy cartilage of proteoglycan synthesis rate as a measure of cartilage matrix synthesis (pg synthesis); percentage release of ... effects of these NSAIDs. By inhibiting joint inflammation, they may indirectly be benefi- cial to cartilage, specifically when inflammation is primary in the cause of cartilage damage...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis" potx
... 39:443-455. 20. Kumar A, Takada Y, Boriek AM, Aggarwal BB: Nuclear factor-κB: its role in health and disease. J Mol Med 2004, 82:434-448. 21. Hashimoto F, Oyaizu N, Kalyanaraman VS, Pahwa S: Modulation of Bcl-2 ... separated by 12% SDS-PAGE and analysed by immunoblotting with an antibody against active caspase-3. Stimulation of the cultures with IL-1β resulted in a time-dependent...
Ngày tải lên: 09/08/2014, 14:22