Báo cáo y học: "Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)" pptx
Báo cáo y học: "Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)" pptx
... legal representatives. Biomarker evaluations In the PROWESS trial, plasma samples were obtained at baseline (day of randomization) and daily through to study day 7. A central laboratory (Covance ... Central Laboratory Services, Indianapolis, IN, USA) performed all assays. The PC activity assay was performed on a STA ® coagulation analyzer using the STA ® -Staclot ® Protein C kit...
Ngày tải lên: 13/08/2014, 08:21
Báo cáo y học: "Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve" pdf
... are regarded as high in control individuals may be inappropriately Table 1 Clinical and laboratory data on admission in patients with septic shock or multiple trauma, and age- and sex-matched control patients Parameter ... a large group of critically ill patients and also found markedly decreased DHEAS levels in both males and females, mainly in those patients with a...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Clinical review: Extracorporeal blood purification in severe sepsis" pdf
... (i.e. monocyte) dysfunction [16]. Both the proinflammatory and anti-inflammatory cascades interact with each other, and form a complex network that is con- stantly trying to balance and restore immunologic ... Further- more, the application of HVHF routinely in humans raises sub- stantial organizational, technical, and financial issues. Removal rates and clearances of the diff...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: "Protein C as a surrogate end-point for clinical trials of sepsis" docx
... potential biomarker in severe sepsis and a possible tool for monitoring treatment with Drotrecogin alfa (activated). Critical Care 2008, 12:R45. 2. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut ... Cardiac Arrhythmia Suppression Trial (CAST) Investigators: Preliminary report: effect of encainide and flecainide on mor- tality in a randomized trial...
Ngày tải lên: 13/08/2014, 10:20
Báo cáo y học: " Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome" pot
... these analyses. Samples In the PROWESS trial, plasma samples were obtained at baseline and daily through study day 7. A central laboratory (Covance Central Laboratory Services, Indianapolis, IN, ... associated with increased morbidity and mortality APACHE = Acute Physiology and Chronic Health Evaluation; DrotAA = drotrecogin alfa (activated); IL = interleukin; PROWESS = Recom...
Ngày tải lên: 12/08/2014, 23:24
Báo cáo Y học: Functional assignment of motifs conserved in b1,3-glycosyltransferases A mutagenesis study of murine UDP-galactose:b-N-acetylglucosamine b1,3-galactosyltransferase-I pptx
... (5¢)3¢) C7 3A AAATGAGCCCAACAAAG CCGAGAAAAACATT I9 7A- R9 8A AATTTGATGCTCGACAGGCT GCCGCGGAGACATGG W10 1A CAATCCGGGAGACA GCTGGTGATGAAAA F11 6A- L11 7A- L11 8A- G11 9A TAGCCACACTTG CAGCCGCGGCCAAAAATG W16 2A TTAATGGGGATGAGAGCGGTT GCCACTTTCT C16 7A ... AGCAACTATCCACCGTTC GCTTCAGGGACTG E26 4A TGCTTCATCTTG CTGACGTGTACGTGGGACT C27 1A ATGTGTACGTGGGACTGGCACTTCGAAAGC C29 5A AAAATGGCCTACAGTTTA G...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx
... towards the iron (Fig. 1). We also propose that Arg266 forms a salt bridge with the carboxyl group of the a- aminoadipoyl- side-chain of penicillin N (1), with arginines 74 and 75 apparently playing ... con- version. Steady-state kinetic analyses were carried out on wild-type enzyme and those mutants catalysing significant penicillin oxidation. Arginines 74, 75 and 266 In the ca...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: The C-terminal region of ammodytoxins is important but not sufficient for neurotoxicity pot
... another high-affinity binding protein for Atxs was isolated and identified as calmodulin (CaM) [19], indicating that this highly conserved, Ca 2+ -sensing regulatory molecule [20] mayplayaroleinthesPLA 2 -neurotoxicity. In ... IIA sPLA 2 s. Ammody- toxins (Atxs) are presynaptic sPLA 2 neurotoxins, ammo- dytins (Atns) I 1 and I 2 are nontoxic sPLA 2 s, and AtnL is a myotoxic but enzy...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis" pdf
... using a Nikon optical system illuminated by a fibre optic light source. Images were analysed and recorded with a Hitachi CCD digital camera. Microvascular damage was analysed and quantified using ... visualized using 3-amino-9-ethyl- carbazole and then washed in tap water, counterstained with haematoxylin and aqueously mounted with Crystal-Mount (Biomeda, CA, USA). Secti...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Giant hepatocellular adenoma as cause of severe abdominal pain: a case report" pot
... abdominal disease and reported that she had been taking a contraceptive pill for the last ten years. Clinical examination of the abdomen revealed a painful, palpable mass with regular margins of about ... regarding the therapeutic approach to asymptomatic patients, surgery is probably indicated in large-size HCAs with or without abdominal symptoms in order to avoid certain com...
Ngày tải lên: 11/08/2014, 10:22