Báo cáo y học: " Formulas Competing risks models and time-dependent covariates" doc

... the Commentary Competing risks models and time-dependent covariates Adrian Barnett and Nick Graves Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, ... for nosocomial pneumonia and mortality in an intensive care unit [1]. Competing risks models offer significant advantages over standard survival analysis [2]. In a standa...

Ngày tải lên: 13/08/2014, 08:21

... anxiety, irritability personality changes, even suicide, depression or acute psychosis. Ribavirin side effect included anemia, renal dysfunction of coronary artery. Fetal abnormality and fatality ... level production and secretion of HCV virions hence this system expands the scope of tools present for HCV study [14,15]. Many patients remain asymptomatic for years and are only detected o...

Ngày tải lên: 12/08/2014, 02:20

... T-cell leukemia virus type 1. Retrovirology 2005, 2:32. 168. Lei YC, Tian YJ, Ding HH, Wang BJ, Yang Y, Hao YH, Zhao XP, Lu MJ, Gong FL, Yang DL: N-terminal and C-terminal cytosine deam- inase domain ... activity remains unclear. Catalytically inactive APOBEC3F showed similar antiviral potency than the wild type protein when ana- lyzed in transiently transfected 293T cells [89]; catalyti-...

Ngày tải lên: 13/08/2014, 05:21

Ngày tải lên: 13/08/2014, 16:21

... in their activity almost as frequently as the promoters of differentially expressed genes. Our results imply that although many promoters may differ in activity between humans and chimpanzees, ... three humans and three chimpanzees in brain and liver using Affymetrix HG U95A and HG U95Av2 arrays [6]. All microarray analysis was performed using the MAS 5.0 software package from Affymet...

Ngày tải lên: 14/08/2014, 14:21

... ppaatthhwwaayyss Both TRF1 and TRF2 are intimately linked with DNA damage response pathways. The ss/dsDNA structure at the telomere could be perceived by the cell as DNA damage, and TRF1 and TRF2 ... of DNA damage, and can be phosphorylated by ATM both in vivo and in vitro [48,49]. Phosphorylation of TRF1 by ATM leads to impairment of TRF1’s capacity to interact with DNA [49], and...

Ngày tải lên: 14/08/2014, 20:22

... antibodies to mice that are locally injected in one knee joint with poly-L-lysine-coupled lysozyme. Poly-L- lysine-coupled lysozyme is highly cationic and sufficiently large to be retained in the ... dominant early inflam- matory cytokine in all models, it is the pivotal cytokine in inhibition of chondrocyte proteoglycan synthesis in the articular cartilage in all models studied so far...

Ngày tải lên: 09/08/2014, 14:22

... 173 7.3 142 5.6 ≧ 4 wk early 142 2.9 71 3.0 71 2.8 Family history of asthma† Yes 140 3.1 68 3.1 72 3.1 Family history of atopy*† Yes 1257 25.0 641 25.0 643 25.0 Family income**† ≦ 400,000 1750 ... 2.65 (1.39,5.03) *Models are adjusted for age, sex, parental education, family history of asthma, family history of atopy, gestational age, and community. Tsai et al. Respiratory Research 2010,...

Ngày tải lên: 12/08/2014, 11:20

... and physostigmine; interestingly, as in most things, septic delay of treatment beyond 6 hours negated any positive effects on survival. So far, studies on the cholinergic inflammatory pathway ... nicotine (400 μg/kg), physostigmine (80 μg/kg) and neostigmine (80 μg/kg) demonstrated improved survival, and treatment with physostigmine significantly reduced lethality as efficiently as dire...

Ngày tải lên: 13/08/2014, 08:21

... Substitution and Insulin Therapy in Severe Sepsis (VISEP) study; hospital mortality for Van den Berghe and colleagues’ surgical ICU (SICU) study; and ICU mortality for the GLUCONTROL study and Arabi and ... [20]. In summary, hyperglycaemia is common in critically ill patients and its occurrence is clearly associated with a worse outcome; thus, it is natural to ask whether hypergly...

Ngày tải lên: 13/08/2014, 08:21