Báo cáo y học: "Lost in translation? The pursuit of lung-protective ventilation" doc

... albeit in conjunction with existing data – supportive of further study and potentially, a therapeutic trial. The incidence of ALI/ARDS in the study by the Irish Critical Care Trials Group, 27% of ... for the discussion and advancement of clinical critical care practice. The data regarding statin use are tantalizing, and add to the growing debate and interest regarding...

Ngày tải lên: 13/08/2014, 08:21

... not to be floating past, but re- treating into the very depths of the azure. In front of the open window of a handsome house, in one of the outlying streets of O * * * the capital of a Government, ... rosy clouds seemed hardly to move across the sky but to be sinking into its depths of blue. In a handsome house in one of the outlying streets of the gov...

Ngày tải lên: 07/03/2014, 22:20

... of peptidyl arginine deiminase (PADI) activity appears also to be involved in the maintenance of immunological tolerance to antigens. Thus, citrullination of proteins in RA patients may unmask ... early indicators of a definite break in tolerance and may provide insight into the pathogenesis of RA. This raises the possibility to predict RA development in high-risk popu...

Ngày tải lên: 09/08/2014, 06:22

... is a group of inflammatory diseases, with ankylosing spondylitis as the prototype. SpA affects the axial skeleton, entheses, joints and, at times, the eyes. This study tested the hypothesis that ... purposes) Introduction Axial spondyloarthropathy (SpA) is a family of polygenic inflam- matory diseases for which the pathophysiology is complex, with much remaining unknown. Ankylos...

Ngày tải lên: 09/08/2014, 14:22

... and other cell types [99,100]. Therefore, one of the functions of MAP kinase signaling pathway may be to regulate the levels of cytokines or interleukines, thereby controlling cell mitosis in the ... and the fatty acid translocase [53]. Recently, the idea of a link between PPARγ and the insulin signaling has been reinforced by the finding that the c-Cbl-associat- ed...

Ngày tải lên: 13/08/2014, 13:20

... [5-7]. The lack of findings of clinically relevant effects of nutritional therapy in earlier studies might thus be explained by not attaining adequate provision of energy and protein. In the present ... be detected. Reaching only the energy target and not attaining 1.2 g pro- tein/day in females results in less favorable outcomes than when both energy and protein goals a...

Ngày tải lên: 13/08/2014, 18:22

... unusual neurological injuries, including focal brain injury due to vascular disruption, spinal cord injury and global anoxic injury following asphyxial cardiac arrest. In these conditions, any Commentary New indications ... and there were numerous anecdotal reports of the use of TH in the treatment of neurological injury following head injury, stroke and anoxic brain injury [1]....

Ngày tải lên: 12/08/2014, 20:20

... caused by C1-inhibitor deficiency. These agents inhibit the release or block the activity of bradykinin, the primary mediator of vascular permeabil- ity associated with HAE. They do not address the ... activation of a number of pathways – including, in particular, the complement and contact systems, and to some extent, the fibrinolysis and coagulation systems. Current fi...

Ngày tải lên: 13/08/2014, 13:22

... TNF-activated NFB-DNA binding activity. The regulation of NFB-DNA binding in primary cells can therefore be explained by the non- specific effect of DMSO on NFB activation. In the present study we determined ... cate- gorized by the molecular function of their protein products into categories that included hyaluronic acid binding activity (including Agc1 and Hapln1) and...

Ngày tải lên: 09/08/2014, 01:22