Báo cáo y học: "Unmeasured anions: the unknown unknown" pot
... alkalosis can mask their presence. Likely culprits vary with the clinical scenario, but the search usually starts with L-lactate and β- hydroxybutyrate. During this process, stoichiometry is tracked between ... likely. Unfortunately, the AG is a flawed instrument. Both sensitivity and specificity are reduced by perturbations of albumin (remembering that albumin negative charge forms t...
Ngày tải lên: 13/08/2014, 08:21
... where the large peaks attributable to acetoacetate and β-hydroxybutyrate are clearly seen [24]. These preliminary results led us to examine the anions of the Krebs cycle using enzyme assay (we ... anions usually associated with the Krebs cycle may contribute to the observed anion or ‘strong-ion’ gap. Although these observations go no way to explaining their genesis, they may provide...
Ngày tải lên: 12/08/2014, 23:24
... step forwards to assess the utility of these questionnaires in another practice setting. Therefore the aim of this observational study was to assess the utility of the MYMOP2 and W-BQ12 health outcomes ... utilised for the study. Patients were invited to participate in the study if they were: over the age of 18 years; had no treatment from any health professional for their compl...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... with great bravery to return to the clinic and to obtain their medication refills. ▪ Patients really surprised us. They walked distances, they ran away, they tried again, they came back. I remember ... them to go on the roads and try to get [to clinic]. The risks to personal safety were seen to vary based on the fam- ilies' tribal affiliation, their location, and whether they wer...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... 5. de Godoy JM, de Godoy Mde F. Physiopathological hypothesis of cellulite. Open Cardiovasc Med J. 2009;31(3):96-7. 6. Godoy JMP, Almeida EMMZNM, Silva SH, Godoy MFG. Pilot study of the intensive ... until the edema is controlled. Another important aspect to be analyzed is the assessment of all changes that may lead to tissue ac- cumulation such as in obesity, lipedema and lymph...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... components by use of the inverse Diels Alder technology. The high chemical stability and the ease of synthesis qualify these polyamide building blocks as favourites for intracellular delivery and ... Germany. The synthesis of the Reppe Anhy- dride was carried out as documented by Reppe [16]. The reaction to tetracy- clo-[5.4.2 1,7 .O 2,6 .O 8,11 ]3,5-dioxo-4-aza-9,12-tridecadie...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"
... to the third minutes after that were statistically different between the study groups (P= 0.016). Post Hoc Tukey test showed there was statistical difference in HR between the ball and the ... hemodynamic responses between the study groups. P<0.05 was considered statistically significant. Results There were no statistical differences in the de- mographic data between t...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"
... Synthesis of the PNA building block backbone In the next step, the synthesis of the PNA back- bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection occurred as described by Atherton ... Sheppard.[40] Synthesis of the Fmoc-C2-glycine-tert-butyl ester The synthesis of the peptide nucleic acid back- bone requires the introduction of protecting groups as shown i...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"
... pharmacokinetics are the drug transporters and the metabolizing en- zymes [7,9]. CYP3A, the primary subfamily of the cytoch- rome P450 (CYP) enzymatic system, is responsible for the metabolism of ... Specifically; tacro- limus is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 polymorphisms seem to affect tacrolimus kinetics at a greater degree com- pared to CYP3...
Ngày tải lên: 26/10/2012, 09:32
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... group was similar as the frequency of 0.21 reported by Chen et al. in their study for chd patients derived from the lipoprotein coronary atherosclerosis study. Conversely, Skogsberg et al. ... The frequency of the C-allele was 0.24 and the genotypes were distributed according to the Hardy Weinberg Equilibrium. Overall the C allele frequency was higher in patients with coro...
Ngày tải lên: 31/10/2012, 17:03